Chowdary (2006)

John Ramey edited this page Jan 11, 2016 · 3 revisions


The authors investigated 52 matched pairs of tissues from colon and breast tumors using Affymetrix U133A arrays and ribonucleic-acid (RNA) amplification. Each tissue pair was gathered from the same patient and consisted of a snap-frozen tissue and a tissue suspended in a RNAlater preservative. Overall, 31 breast-cancer and 21 colon-cancer pairs were gathered, resulting in K = 2 classes with n_1 = 62 and n_2 = 42. A purpose of the study was to determine whether the disease state could be identified using 22,283 gene-expression profiles.

Sample Size Number of Features Number of Classes Disease
104 22,283 2 Breast Cancer


Link to Original Paper

BibTeX Record

author = {Chowdary, Dondapati and Lathrop, Jessica and Skelton, Joanne and Curtin, Kathleen and Briggs, Thomas and Zhang, Yi and Yu, Jack and Wang, Yixin and Mazumder, Abhijit},
title = {{Prognostic Gene Expression Signatures Can Be Measured in Tissues Collected in RNAlater Preservative}},
journal = {The Journal of Molecular Diagnostics},
year = {2006},
volume = {8},
number = {1},
pages = {31--39},
month = feb