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README.md

tlcnet

Regulatory network reconstruction via time-lagged correlation analysis of gene expression and motif scanning data

This repository contains the MATLAB code for reconstructing a gene regulatory network from time-series gene expression data and transcription factor binding site motif scanning data. The code was used in the analysis published in the 2008 article Uncovering a macrophage transcriptional program by integrating evidence from motif scanning and expression dynamics (Ramsey et al., PLOS Comput Biol., 2008).

The MATLAB code in this project was written by Stephen Ramsey (@saramsey) except where otherwise indicated in the header comments.

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Regulatory network reconstruction via time-lagged correlation analysis of gene expression and motif scanning data

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