diff --git a/src/PickerPanel.tsx b/src/PickerPanel.tsx
index ea36b4c72..9527e986e 100644
--- a/src/PickerPanel.tsx
+++ b/src/PickerPanel.tsx
@@ -27,14 +27,14 @@ import type { DateRender } from './panels/DatePanel/DateBody';
 import DatetimePanel from './panels/DatetimePanel';
 import DecadePanel from './panels/DecadePanel';
 import MonthPanel from './panels/MonthPanel';
-import type { MonthCellRender } from './panels/MonthPanel/MonthBody';
+import { MONTH_COL_COUNT, type MonthCellRender } from './panels/MonthPanel/MonthBody';
 import QuarterPanel from './panels/QuarterPanel';
 import type { SharedTimeProps } from './panels/TimePanel';
 import TimePanel from './panels/TimePanel';
 import WeekPanel from './panels/WeekPanel';
 import YearPanel from './panels/YearPanel';
 import RangeContext from './RangeContext';
-import { isEqual } from './utils/dateUtil';
+import { isEqual, WEEK_DAY_COUNT } from './utils/dateUtil';
 import getExtraFooter from './utils/getExtraFooter';
 import getRanges from './utils/getRanges';
 import { getLowerBoundTime, setDateTime, setTime } from './utils/timeUtil';
@@ -125,6 +125,9 @@ type MergedPickerPanelProps<DateType> = {
   picker?: PickerMode;
 } & OmitType<DateType>;
 
+// Calendar picker type
+const CALENDAR_PANEL_MODE: PanelMode[] = ['date', 'month'];
+
 function PickerPanel<DateType>(props: PickerPanelProps<DateType>) {
   const {
     prefixCls = 'rc-picker',
@@ -297,9 +300,49 @@ function PickerPanel<DateType>(props: PickerPanelProps<DateType>) {
     }
   };
 
+  const isSelectable = (key) => {
+    if (CALENDAR_PANEL_MODE.includes(mergedMode)) {
+      let date;
+      let operationFnc;
+      const isDateMode = mergedMode === 'date';
+      if (key === KeyCode.PAGE_UP || key === KeyCode.PAGE_DOWN) {
+        operationFnc = isDateMode ? generateConfig.addMonth : generateConfig.addYear;
+      } else {
+        operationFnc = isDateMode ? generateConfig.addDate : generateConfig.addMonth;
+      }
+
+      switch (key) {
+        case KeyCode.LEFT:
+        case KeyCode.PAGE_UP:
+          date = operationFnc(viewDate, -1);
+          break;
+        case KeyCode.RIGHT:
+        case KeyCode.PAGE_DOWN:
+          date = operationFnc(viewDate, 1);
+          break;
+        case KeyCode.UP:
+        case KeyCode.DOWN:
+          date = operationFnc(
+            viewDate,
+            Number(
+              `${key === KeyCode.UP ? '-' : ''}${isDateMode ? WEEK_DAY_COUNT : MONTH_COL_COUNT}`,
+            ),
+          );
+          break;
+      }
+
+      if (date) {
+        return !disabledDate?.(date);
+      }
+    }
+    return true;
+  };
+
   // ========================= Interactive ==========================
   const onInternalKeyDown = (e: React.KeyboardEvent<HTMLElement>) => {
     if (panelRef.current && panelRef.current.onKeyDown) {
+      let selectable = true;
+      const { which } = e;
       if (
         [
           KeyCode.LEFT,
@@ -309,11 +352,18 @@ function PickerPanel<DateType>(props: PickerPanelProps<DateType>) {
           KeyCode.PAGE_UP,
           KeyCode.PAGE_DOWN,
           KeyCode.ENTER,
-        ].includes(e.which)
+        ].includes(which)
       ) {
         e.preventDefault();
+        if (which !== KeyCode.ENTER && tabIndex === 0) {
+          selectable = isSelectable(which);
+        }
+      }
+
+      // Cannot use keyboard to select disabled date
+      if (selectable) {
+        return panelRef.current.onKeyDown(e);
       }
-      return panelRef.current.onKeyDown(e);
     }
 
     /* istanbul ignore next */
@@ -379,7 +429,6 @@ function PickerPanel<DateType>(props: PickerPanelProps<DateType>) {
   delete pickerProps.onChange;
   delete pickerProps.onSelect;
 
-
   switch (mergedMode) {
     case 'decade':
       panelNode = (
diff --git a/tests/keyboard.spec.tsx b/tests/keyboard.spec.tsx
index 808145fc3..cb79e65e6 100644
--- a/tests/keyboard.spec.tsx
+++ b/tests/keyboard.spec.tsx
@@ -534,16 +534,56 @@ describe('Picker.Keyboard', () => {
       );
 
       fireEvent.focus(document.querySelector('.rc-picker-panel'));
-
-      // 9-10 is disabled
+      // 9-02、9-04、9-10 is disabled
+      panelKeyDown(KeyCode.LEFT);
+      panelKeyDown(KeyCode.RIGHT);
       panelKeyDown(KeyCode.DOWN);
-      expect(isSame(onSelect.mock.calls[0][0], '1990-09-10')).toBeTruthy();
-      expect(onChange).not.toHaveBeenCalled();
+      expect(onSelect).not.toHaveBeenCalled();
+
+      // 7-27、8-27 is enabled
+      panelKeyDown(KeyCode.UP);
+      expect(isSame(onSelect.mock.calls[0][0], '1990-08-27')).toBeTruthy();
+      onSelect.mockReset();
+      panelKeyDown(KeyCode.PAGE_UP);
+      expect(isSame(onSelect.mock.calls[0][0], '1990-07-27')).toBeTruthy();
+      onSelect.mockReset();
+      panelKeyDown(KeyCode.PAGE_DOWN);
+      expect(isSame(onSelect.mock.calls[0][0], '1990-08-27')).toBeTruthy();
+    });
+
+    it('month panel', () => {
+      const onChange = jest.fn();
+      const onSelect = jest.fn();
+      const now = new Date();
+      render(
+        <MomentPickerPanel
+          picker="month"
+          onSelect={onSelect}
+          onChange={onChange}
+          disabledDate={(date) => date.month() < now.getMonth()}
+        />,
+      );
+
+      fireEvent.focus(document.querySelector('.rc-picker-panel'));
 
-      // 9-17 is enabled
+      // PAGE_UP and PAGE_DOWN do not trigger the select
+      panelKeyDown(KeyCode.PAGE_UP);
+      panelKeyDown(KeyCode.PAGE_DOWN);
+      expect(onSelect).not.toHaveBeenCalled();
+
+      // The disabled date is before August
+      panelKeyDown(KeyCode.LEFT);
+      panelKeyDown(KeyCode.UP);
+      expect(onSelect).not.toHaveBeenCalled();
+
+      // August and subsequent dates are enable
+      panelKeyDown(KeyCode.RIGHT);
+      expect(isSame(onSelect.mock.calls[0][0], '1990-10-03')).toBeTruthy();
+      onSelect.mockReset();
+      panelKeyDown(KeyCode.LEFT);
+      onSelect.mockReset();
       panelKeyDown(KeyCode.DOWN);
-      expect(isSame(onSelect.mock.calls[1][0], '1990-09-17')).toBeTruthy();
-      expect(isSame(onChange.mock.calls[0][0], '1990-09-17')).toBeTruthy();
+      expect(isSame(onSelect.mock.calls[0][0], '1990-12-03')).toBeTruthy();
     });
   });
 });