diff --git a/build.cake b/build.cake
index faedaa8dd8..80e4cb85f2 100644
--- a/build.cake
+++ b/build.cake
@@ -94,7 +94,7 @@ Action<string, string> Package = (nuspec, basePath) =>
         RequireLicenseAcceptance = false,
 
         Version                  = semVersion,
-        Tags                     = new [] {"mvvm", "reactiveui", "Rx", "Reactive Extensions", "Observable", "LINQ", "Events", "xamarin", "android", "ios", "forms", "monodroid", "monotouch", "xamarin.android", "xamarin.ios", "xamarin.forms", "wpf", "winforms", "uwp", "winrt", "net45", "netcore", "wp", "wpdev", "windowsphone", "windowsstore"},
+        Tags                     = new [] {"mvvm", "reactiveui", "Rx", "Reactive Extensions", "Observable", "LINQ", "Events", "xamarin", "android", "ios", "forms", "monodroid", "monotouch", "xamarin.android", "xamarin.ios", "xamarin.forms", "wpf", "winforms", "uwp", "winrt", "net46", "netcore", "wp", "wpdev", "windowsphone", "windowsstore"},
         ReleaseNotes             = new List<string>(releaseNotes.Notes),
 
         Symbols                  = true,
@@ -201,7 +201,7 @@ Task("GenerateEvents")
     generate("mac");
     generate("xamforms");
 
-    generate("net45");
+    generate("net46");
     
     generate("wpa81");
     generate("uwp");
@@ -235,7 +235,7 @@ Task("BuildEvents")
     build("ReactiveUI.Events_MAC.sln");
     build("ReactiveUI.Events_XamForms.sln");
 
-    build("ReactiveUI.Events_NET45.sln");
+    build("ReactiveUI.Events_NET46.sln");
 
     build("ReactiveUI.Events_WPA81.sln");
     build("ReactiveUI.Events_UWP.sln");
@@ -320,7 +320,7 @@ Task("RunUnitTests")
     .IsDependentOn("BuildReactiveUI")
     .Does(() =>
 {
-    XUnit2("./src/ReactiveUI.Tests/bin/Release/Net45/ReactiveUI.Tests_Net45.dll", new XUnit2Settings {
+    XUnit2("./src/ReactiveUI.Tests/bin/Release/Net46/ReactiveUI.Tests_Net46.dll", new XUnit2Settings {
         OutputDirectory = artifactDirectory,
         XmlReportV1 = true,
         NoAppDomain = true
diff --git a/packages/repositories.config b/packages/repositories.config
index bf1beb5fc6..688378d3f9 100644
--- a/packages/repositories.config
+++ b/packages/repositories.config
@@ -33,11 +33,11 @@
   <repository path="..\Playground-Wpa81\Playground-Wpa81.Windows\packages.config" />
   <repository path="..\Playground-Wpa81\Playground-Wpa81.WindowsPhone\packages.config" />
   <repository path="..\ReactiveUI.AndroidSupport\packages.config" />
-  <repository path="..\ReactiveUI.Blend\packages.ReactiveUI.Blend_Net45.config" />
+  <repository path="..\ReactiveUI.Blend\packages.ReactiveUI.Blend_Net46.config" />
   <repository path="..\ReactiveUI.Blend\packages.ReactiveUI.Blend_WinRT.config" />
   <repository path="..\ReactiveUI.Blend\packages.ReactiveUI.Blend_WP8.config" />
   <repository path="..\ReactiveUI.Events\packages.ReactiveUI.Events_Android_XS.config" />
-  <repository path="..\ReactiveUI.Events\packages.ReactiveUI.Events_Net45.config" />
+  <repository path="..\ReactiveUI.Events\packages.ReactiveUI.Events_Net46.config" />
   <repository path="..\ReactiveUI.Events\packages.ReactiveUI.Events_WinRT.config" />
   <repository path="..\ReactiveUI.Events\packages.ReactiveUI.Events_WinRT80.config" />
   <repository path="..\ReactiveUI.Events\packages.ReactiveUI.Events_WP8.config" />
@@ -45,16 +45,16 @@
   <repository path="..\ReactiveUI.Events\packages.ReactiveUI.Events_WPA81.config" />
   <repository path="..\ReactiveUI.Testing\packages.ReactiveUI.Testing_Android.config" />
   <repository path="..\ReactiveUI.Testing\packages.ReactiveUI.Testing_Mac.config" />
-  <repository path="..\ReactiveUI.Testing\packages.ReactiveUI.Testing_Net45.config" />
+  <repository path="..\ReactiveUI.Testing\packages.ReactiveUI.Testing_Net46.config" />
   <repository path="..\ReactiveUI.Testing\packages.ReactiveUI.Testing_WinRT.config" />
   <repository path="..\ReactiveUI.Testing\packages.ReactiveUI.Testing_WP8.config" />
   <repository path="..\ReactiveUI.Tests\packages.ReactiveUI.Tests_Android.config" />
-  <repository path="..\ReactiveUI.Tests\packages.ReactiveUI.Tests_Net45.config" />
+  <repository path="..\ReactiveUI.Tests\packages.ReactiveUI.Tests_Net46.config" />
   <repository path="..\ReactiveUI.Winforms\packages.config" />
   <repository path="..\ReactiveUI.XamForms\packages.config" />
   <repository path="..\ReactiveUI\packages.ReactiveUI.config" />
   <repository path="..\ReactiveUI\packages.ReactiveUI_Android.config" />
-  <repository path="..\ReactiveUI\packages.ReactiveUI_Net45.config" />
+  <repository path="..\ReactiveUI\packages.ReactiveUI_Net46.config" />
   <repository path="..\ReactiveUI\packages.ReactiveUI_UAP.config" />
   <repository path="..\ReactiveUI\packages.ReactiveUI_WinRT.config" />
   <repository path="..\ReactiveUI\packages.ReactiveUI_WinRT80.config" />
diff --git a/src/EventBuilder/App.config b/src/EventBuilder/App.config
index 71a44c90c7..ed590d737a 100644
--- a/src/EventBuilder/App.config
+++ b/src/EventBuilder/App.config
@@ -1,7 +1,7 @@
 <?xml version="1.0" encoding="utf-8"?>
 <configuration>
   <startup>
-    <supportedRuntime version="v4.0" sku=".NETFramework,Version=v4.5"/>
+    <supportedRuntime version="v4.0" sku=".NETFramework,Version=v4.6"/>
   </startup>
   <appSettings>
     <add key="serilog:minimum-level" value="Verbose"/>
diff --git a/src/EventBuilder/CommandLineOptions.cs b/src/EventBuilder/CommandLineOptions.cs
index bd50898368..78b08cb396 100644
--- a/src/EventBuilder/CommandLineOptions.cs
+++ b/src/EventBuilder/CommandLineOptions.cs
@@ -10,7 +10,7 @@ public enum AutoPlatform
         Android,
         iOS,
         Mac,
-        NET45,
+        NET46,
         XamForms,
         UWP,
         WP81,
@@ -24,7 +24,7 @@ public class CommandLineOptions
 
         [Option('p', "platform", Required = true,
             HelpText =
-                "Platform to automatically generate. Possible options include: NONE, ANDROID, IOS, NET45, MAC, UWP, WP81, WPA81, XAMFORMS"
+                "Platform to automatically generate. Possible options include: NONE, ANDROID, IOS, NET46, MAC, UWP, WP81, WPA81, XAMFORMS"
             )]
         public AutoPlatform Platform { get; set; }
 
diff --git a/src/EventBuilder/EventBuilder.csproj b/src/EventBuilder/EventBuilder.csproj
index 3703b2514f..5bca74cd9f 100644
--- a/src/EventBuilder/EventBuilder.csproj
+++ b/src/EventBuilder/EventBuilder.csproj
@@ -1,5 +1,5 @@
 <?xml version="1.0" encoding="utf-8"?>
-<Project ToolsVersion="4.0" DefaultTargets="Build" xmlns="http://schemas.microsoft.com/developer/msbuild/2003">
+<Project ToolsVersion="12.0" DefaultTargets="Build" xmlns="http://schemas.microsoft.com/developer/msbuild/2003">
   <Import Project="$(MSBuildExtensionsPath)\$(MSBuildToolsVersion)\Microsoft.Common.props" Condition="Exists('$(MSBuildExtensionsPath)\$(MSBuildToolsVersion)\Microsoft.Common.props')" />
   <PropertyGroup>
     <Configuration Condition=" '$(Configuration)' == '' ">Debug</Configuration>
@@ -9,7 +9,7 @@
     <AppDesignerFolder>Properties</AppDesignerFolder>
     <RootNamespace>EventBuilder</RootNamespace>
     <AssemblyName>EventBuilder</AssemblyName>
-    <TargetFrameworkVersion>v4.5</TargetFrameworkVersion>
+    <TargetFrameworkVersion>v4.6</TargetFrameworkVersion>
     <FileAlignment>512</FileAlignment>
     <AutoGenerateBindingRedirects>true</AutoGenerateBindingRedirects>
     <TargetFrameworkProfile />
@@ -113,7 +113,7 @@
     <Compile Include="Platforms\iOS.cs" />
     <Compile Include="Platforms\IPlatform.cs" />
     <Compile Include="Platforms\Mac.cs" />
-    <Compile Include="Platforms\Net45.cs" />
+    <Compile Include="Platforms\Net46.cs" />
     <Compile Include="Platforms\UWP.cs" />
     <Compile Include="Platforms\WP81.cs" />
     <Compile Include="Platforms\WPA81.cs" />
diff --git a/src/EventBuilder/Platforms/Net45.cs b/src/EventBuilder/Platforms/Net46.cs
similarity index 65%
rename from src/EventBuilder/Platforms/Net45.cs
rename to src/EventBuilder/Platforms/Net46.cs
index 5135e094bd..c3c91ccef8 100644
--- a/src/EventBuilder/Platforms/Net45.cs
+++ b/src/EventBuilder/Platforms/Net46.cs
@@ -7,21 +7,21 @@
 
 namespace EventBuilder.Platforms
 {
-    public class Net45 : BasePlatform
+    public class Net46 : BasePlatform
     {
-        public Net45()
+        public Net46()
         {
             if (PlatformHelper.IsRunningOnMono())
             {
-                throw new NotSupportedException("Building events for NET45 on Mac is not implemented yet.");
+                throw new NotSupportedException("Building events for NET46 on Mac is not implemented.");
             }
             else
             {
-                Assemblies.Add(@"C:\Program Files (x86)\Reference Assemblies\Microsoft\Framework\.NETFramework\v4.5\WindowsBase.dll");
-                Assemblies.Add(@"C:\Program Files (x86)\Reference Assemblies\Microsoft\Framework\.NETFramework\v4.5\PresentationCore.dll");
-                Assemblies.Add(@"C:\Program Files (x86)\Reference Assemblies\Microsoft\Framework\.NETFramework\v4.5\PresentationFramework.dll");
+                Assemblies.Add(@"C:\Program Files (x86)\Reference Assemblies\Microsoft\Framework\.NETFramework\v4.6\WindowsBase.dll");
+                Assemblies.Add(@"C:\Program Files (x86)\Reference Assemblies\Microsoft\Framework\.NETFramework\v4.6\PresentationCore.dll");
+                Assemblies.Add(@"C:\Program Files (x86)\Reference Assemblies\Microsoft\Framework\.NETFramework\v4.6\PresentationFramework.dll");
 
-                CecilSearchDirectories.Add(@"C:\Program Files (x86)\Reference Assemblies\Microsoft\Framework\.NETFramework\v4.5");
+                CecilSearchDirectories.Add(@"C:\Program Files (x86)\Reference Assemblies\Microsoft\Framework\.NETFramework\v4.6");
 
             }
 
diff --git a/src/EventBuilder/Program.cs b/src/EventBuilder/Program.cs
index 35d86616dd..13900f9e41 100644
--- a/src/EventBuilder/Program.cs
+++ b/src/EventBuilder/Program.cs
@@ -92,8 +92,8 @@ private static void Main(string[] args)
                             platform = new Mac();
                             break;
 
-                        case AutoPlatform.NET45:
-                            platform = new Net45();
+                        case AutoPlatform.NET46:
+                            platform = new Net46();
                             break;
 
                         case AutoPlatform.XamForms:
diff --git a/src/PerfConsoleRunner/PerfConsoleRunner.csproj b/src/PerfConsoleRunner/PerfConsoleRunner.csproj
index 0925ec0214..621cb63eb2 100644
--- a/src/PerfConsoleRunner/PerfConsoleRunner.csproj
+++ b/src/PerfConsoleRunner/PerfConsoleRunner.csproj
@@ -10,7 +10,7 @@
     <AppDesignerFolder>Properties</AppDesignerFolder>
     <RootNamespace>PerfConsoleRunner</RootNamespace>
     <AssemblyName>PerfConsoleRunner</AssemblyName>
-    <TargetFrameworkVersion>v4.5</TargetFrameworkVersion>
+    <TargetFrameworkVersion>v4.6</TargetFrameworkVersion>
     <TargetFrameworkProfile>
     </TargetFrameworkProfile>
     <FileAlignment>512</FileAlignment>
@@ -59,13 +59,13 @@
     <Compile Include="Properties\AssemblyInfo.cs" />
   </ItemGroup>
   <ItemGroup>
-    <ProjectReference Include="..\ReactiveUI.Blend\ReactiveUI.Blend_Net45.csproj">
+    <ProjectReference Include="..\ReactiveUI.Blend\ReactiveUI.Blend_Net46.csproj">
       <Project>{7866b5b1-5457-43a2-976a-e784eb10f2da}</Project>
-      <Name>ReactiveUI.Blend_Net45</Name>
+      <Name>ReactiveUI.Blend_Net46</Name>
     </ProjectReference>
-    <ProjectReference Include="..\ReactiveUI\ReactiveUI_Net45.csproj">
+    <ProjectReference Include="..\ReactiveUI\ReactiveUI_Net46.csproj">
       <Project>{1ce2d235-8072-4649-ba5a-cfb1af8776e0}</Project>
-      <Name>ReactiveUI_Net45</Name>
+      <Name>ReactiveUI_Net46</Name>
     </ProjectReference>
   </ItemGroup>
   <ItemGroup>
diff --git a/src/PerfConsoleRunner/Program.cs b/src/PerfConsoleRunner/Program.cs
index 0ec4fe6f50..1b30b217aa 100644
--- a/src/PerfConsoleRunner/Program.cs
+++ b/src/PerfConsoleRunner/Program.cs
@@ -21,7 +21,7 @@ public static int Main(string[] args)
             var relDir = "Release";
 #endif
 
-            var testAssembly = Path.Combine(solutionDir, @"ReactiveUI.Tests\bin\Debug\Net45\ReactiveUI.Tests_Net45.dll")
+            var testAssembly = Path.Combine(solutionDir, @"ReactiveUI.Tests\bin\Debug\Net46\ReactiveUI.Tests_Net46.dll")
                 .Replace("Debug", relDir);
 
             Xunit.ConsoleClient.Program.Main(new[] { testAssembly });
diff --git a/src/ReactiveUI-Blend.nuspec b/src/ReactiveUI-Blend.nuspec
index 283006ee58..c7932f6ba8 100644
--- a/src/ReactiveUI-Blend.nuspec
+++ b/src/ReactiveUI-Blend.nuspec
@@ -38,7 +38,7 @@
     <!-- Windows Universal -->
     <file src="bin/Release/UAP10.0/ReactiveUI.Blend_UWP.dll" target="lib/UAP10/ReactiveUI.Blend_UWP.dll" />
     <!-- .NET 4.5 -->
-    <file src="bin/Release/Net45/ReactiveUI.Blend.dll" target="lib/Net45/ReactiveUI.Blend.dll" />
+    <file src="bin/Release/Net46/ReactiveUI.Blend.dll" target="lib/Net46/ReactiveUI.Blend.dll" />
     <!-- Source -->
     <file src="*.cs" target="src" />
   </files>
diff --git a/src/ReactiveUI-Core.nuspec b/src/ReactiveUI-Core.nuspec
index 1a2c46c7ed..7c6b08412b 100644
--- a/src/ReactiveUI-Core.nuspec
+++ b/src/ReactiveUI-Core.nuspec
@@ -61,13 +61,13 @@
     <!-- iOS Unified API -->
     <file src="bin/Release/Xamarin.iOS10/ReactiveUI.dll" target="lib/Xamarin.iOS10/ReactiveUI.dll" />
     <!-- Xamarin Mac Unified API -->
-    <file src="bin/Release/Xamarin.Mac20/ReactiveUI.dll" target="lib/Xamarin.Mac20/ReactiveUI.dll" /> 
+    <file src="bin/Release/Xamarin.Mac20/ReactiveUI.dll" target="lib/Xamarin.Mac20/ReactiveUI.dll" />
     <!-- Windows Store 8.1 -->
     <file src="bin/Release/Portable-Win81+Wpa81/ReactiveUI.dll" target="lib/Portable-Win81+Wpa81/ReactiveUI.dll" />
     <!-- Windows Universal -->
     <file src="bin/Release/UAP10.0/ReactiveUI.dll" target="lib/UAP10/ReactiveUI.dll" />
     <!-- .NET 4.5 -->
-    <file src="bin/Release/Net45/ReactiveUI.dll" target="lib/Net45/ReactiveUI.dll" />
+    <file src="bin/Release/Net46/ReactiveUI.dll" target="lib/Net46/ReactiveUI.dll" />
     <!-- Portable PCL -->
     <file src="bin/Release/portable-net45+netcore45+wpa81+win8+wp8+UAP10+MonoAndroid403+MonoTouch10+Xamarin.iOS10/ReactiveUI.dll" target="lib/portable-net45+netcore45+wpa81+win8+wp8+UAP10+MonoAndroid403+MonoTouch10+Xamarin.iOS10/ReactiveUI.dll" />
     <!-- Source -->
diff --git a/src/ReactiveUI-Events.nuspec b/src/ReactiveUI-Events.nuspec
index e82f3e3770..a8a1e248e5 100644
--- a/src/ReactiveUI-Events.nuspec
+++ b/src/ReactiveUI-Events.nuspec
@@ -30,7 +30,7 @@
     <!-- Windows Universal -->
     <file src="bin/Release/UAP10.0/ReactiveUI.Events.dll" target="lib/UAP10/ReactiveUI.Events.dll" />
     <!-- .NET 4.5 -->
-    <file src="bin/Release/Net45/ReactiveUI.Events.dll" target="lib/Net45/ReactiveUI.Events.dll" />
+    <file src="bin/Release/Net46/ReactiveUI.Events.dll" target="lib/Net46/ReactiveUI.Events.dll" />
     <!-- Source -->
     <file src="*.cs" target="src" />
   </files>
diff --git a/src/ReactiveUI-Testing.nuspec b/src/ReactiveUI-Testing.nuspec
index ddc13b0105..ca9f79cdc9 100644
--- a/src/ReactiveUI-Testing.nuspec
+++ b/src/ReactiveUI-Testing.nuspec
@@ -39,13 +39,13 @@
     <!-- iOS Unified API -->
     <file src="bin/Release/Xamarin.iOS10/ReactiveUI.Testing.dll" target="lib/Xamarin.iOS10/ReactiveUI.Testing.dll" />
     <!-- Xamarin Mac Unified API -->
-     <file src="bin/Release/Xamarin.Mac20/ReactiveUI.Testing.dll" target="lib/Xamarin.Mac20/ReactiveUI.Testing.dll" /> 
+    <file src="bin/Release/Xamarin.Mac20/ReactiveUI.Testing.dll" target="lib/Xamarin.Mac20/ReactiveUI.Testing.dll" />
     <!-- Windows Store 8.1 -->
     <file src="bin/Release/Portable-Win81+WPA81/ReactiveUI.Testing.dll" target="lib/Portable-Win81+WPA81/ReactiveUI.Testing.dll" />
     <!-- Windows Universal -->
     <file src="bin/Release/UAP10.0/ReactiveUI.Testing.dll" target="lib/UAP10/ReactiveUI.Testing.dll" />
     <!-- .NET 4.5 -->
-    <file src="bin/Release/Net45/ReactiveUI.Testing.dll" target="lib/Net45/ReactiveUI.Testing.dll" />
+    <file src="bin/Release/Net46/ReactiveUI.Testing.dll" target="lib/Net46/ReactiveUI.Testing.dll" />
     <!-- Source -->
     <file src="*.cs" target="src" />
   </files>
diff --git a/src/ReactiveUI-Winforms.nuspec b/src/ReactiveUI-Winforms.nuspec
index 3434e789f1..cb81d138b0 100644
--- a/src/ReactiveUI-Winforms.nuspec
+++ b/src/ReactiveUI-Winforms.nuspec
@@ -11,7 +11,7 @@
   </metadata>
   <files>
     <!-- .NET 4.5 -->
-    <file src="bin/Release/Net45/ReactiveUI.Winforms.dll" target="lib/Net45/ReactiveUI.Winforms.dll" />
+    <file src="bin/Release/Net46/ReactiveUI.Winforms.dll" target="lib/Net46/ReactiveUI.Winforms.dll" />
     <!-- Source -->
     <file src="*.cs" target="src" />
   </files>
diff --git a/src/ReactiveUI.Blend/ReactiveUI.Blend_Net45.csproj b/src/ReactiveUI.Blend/ReactiveUI.Blend_Net46.csproj
similarity index 86%
rename from src/ReactiveUI.Blend/ReactiveUI.Blend_Net45.csproj
rename to src/ReactiveUI.Blend/ReactiveUI.Blend_Net46.csproj
index 5399922f98..5452b06190 100644
--- a/src/ReactiveUI.Blend/ReactiveUI.Blend_Net45.csproj
+++ b/src/ReactiveUI.Blend/ReactiveUI.Blend_Net46.csproj
@@ -1,5 +1,5 @@
 <?xml version="1.0" encoding="utf-8"?>
-<Project ToolsVersion="4.0" DefaultTargets="Build" xmlns="http://schemas.microsoft.com/developer/msbuild/2003">
+<Project ToolsVersion="12.0" DefaultTargets="Build" xmlns="http://schemas.microsoft.com/developer/msbuild/2003">
   <PropertyGroup>
     <Configuration Condition=" '$(Configuration)' == '' ">Debug</Configuration>
     <Platform Condition=" '$(Platform)' == '' ">AnyCPU</Platform>
@@ -10,7 +10,7 @@
     <AppDesignerFolder>Properties</AppDesignerFolder>
     <RootNamespace>ReactiveUI.Blend</RootNamespace>
     <AssemblyName>ReactiveUI.Blend</AssemblyName>
-    <TargetFrameworkVersion>v4.5</TargetFrameworkVersion>
+    <TargetFrameworkVersion>v4.6</TargetFrameworkVersion>
     <FileAlignment>512</FileAlignment>
     <SccProjectName>
     </SccProjectName>
@@ -29,21 +29,21 @@
     <DebugSymbols>true</DebugSymbols>
     <DebugType>full</DebugType>
     <Optimize>false</Optimize>
-    <OutputPath>bin\Debug\Net45\</OutputPath>
-    <IntermediateOutputPath>obj\Debug\Net45</IntermediateOutputPath>
-    <DefineConstants>DEBUG;TRACE;NET_45</DefineConstants>
+    <OutputPath>bin\Debug\Net46\</OutputPath>
+    <IntermediateOutputPath>obj\Debug\Net46</IntermediateOutputPath>
+    <DefineConstants>DEBUG;TRACE;NET_46</DefineConstants>
     <ErrorReport>prompt</ErrorReport>
     <WarningLevel>4</WarningLevel>
   </PropertyGroup>
   <PropertyGroup Condition=" '$(Configuration)|$(Platform)' == 'Release|AnyCPU' ">
     <DebugType>pdbonly</DebugType>
     <Optimize>true</Optimize>
-    <OutputPath>bin\Release\Net45\</OutputPath>
-    <IntermediateOutputPath>obj\Release\Net45</IntermediateOutputPath>
-    <DefineConstants>TRACE;NET_45</DefineConstants>
+    <OutputPath>bin\Release\Net46\</OutputPath>
+    <IntermediateOutputPath>obj\Release\Net46</IntermediateOutputPath>
+    <DefineConstants>TRACE;NET_46</DefineConstants>
     <ErrorReport>prompt</ErrorReport>
     <WarningLevel>4</WarningLevel>
-    <DocumentationFile>bin\Release\Net45\ReactiveUI.Blend.xml</DocumentationFile>
+    <DocumentationFile>bin\Release\Net46\ReactiveUI.Blend.xml</DocumentationFile>
   </PropertyGroup>
   <ItemGroup>
     <Reference Include="Microsoft.Expression.Interactions, Version=4.5.0.0, Culture=neutral, PublicKeyToken=31bf3856ad364e35, processorArchitecture=MSIL" />
@@ -91,12 +91,12 @@
     <Compile Include="ObservableTrigger.cs" />
   </ItemGroup>
   <ItemGroup>
-    <None Include="packages.ReactiveUI.Blend_Net45.config" />
+    <None Include="packages.ReactiveUI.Blend_Net46.config" />
   </ItemGroup>
   <ItemGroup>
-    <ProjectReference Include="..\ReactiveUI\ReactiveUI_Net45.csproj">
+    <ProjectReference Include="..\ReactiveUI\ReactiveUI_Net46.csproj">
       <Project>{1ce2d235-8072-4649-ba5a-cfb1af8776e0}</Project>
-      <Name>ReactiveUI_Net45</Name>
+      <Name>ReactiveUI_Net46</Name>
     </ProjectReference>
   </ItemGroup>
   <Import Project="$(MSBuildToolsPath)\Microsoft.CSharp.targets" />
diff --git a/src/ReactiveUI.Blend/packages.ReactiveUI.Blend_Net45.config b/src/ReactiveUI.Blend/packages.ReactiveUI.Blend_Net46.config
similarity index 100%
rename from src/ReactiveUI.Blend/packages.ReactiveUI.Blend_Net45.config
rename to src/ReactiveUI.Blend/packages.ReactiveUI.Blend_Net46.config
diff --git a/src/ReactiveUI.Events/ReactiveUI.Events_Net45.csproj b/src/ReactiveUI.Events/ReactiveUI.Events_Net46.csproj
similarity index 92%
rename from src/ReactiveUI.Events/ReactiveUI.Events_Net45.csproj
rename to src/ReactiveUI.Events/ReactiveUI.Events_Net46.csproj
index a034e4274f..cd3dc7bdd3 100644
--- a/src/ReactiveUI.Events/ReactiveUI.Events_Net45.csproj
+++ b/src/ReactiveUI.Events/ReactiveUI.Events_Net46.csproj
@@ -9,7 +9,7 @@
     <AppDesignerFolder>Properties</AppDesignerFolder>
     <RootNamespace>ReactiveUI.Events</RootNamespace>
     <AssemblyName>ReactiveUI.Events</AssemblyName>
-    <TargetFrameworkVersion>v4.5</TargetFrameworkVersion>
+    <TargetFrameworkVersion>v4.6</TargetFrameworkVersion>
     <FileAlignment>512</FileAlignment>
     <ProjectTypeGuids>{60dc8134-eba5-43b8-bcc9-bb4bc16c2548};{FAE04EC0-301F-11D3-BF4B-00C04F79EFBC}</ProjectTypeGuids>
     <WarningLevel>4</WarningLevel>
@@ -20,8 +20,8 @@
     <DebugSymbols>true</DebugSymbols>
     <DebugType>full</DebugType>
     <Optimize>false</Optimize>
-    <OutputPath>bin\Debug\Net45\</OutputPath>
-    <IntermediateOutputPath>obj\Debug\Net45</IntermediateOutputPath>
+    <OutputPath>bin\Debug\Net46\</OutputPath>
+    <IntermediateOutputPath>obj\Debug\Net46</IntermediateOutputPath>
     <DefineConstants>DEBUG;TRACE</DefineConstants>
     <ErrorReport>prompt</ErrorReport>
     <WarningLevel>4</WarningLevel>
@@ -29,8 +29,8 @@
   <PropertyGroup Condition=" '$(Configuration)|$(Platform)' == 'Release|AnyCPU' ">
     <DebugType>pdbonly</DebugType>
     <Optimize>true</Optimize>
-    <OutputPath>bin\Release\Net45\</OutputPath>
-    <IntermediateOutputPath>obj\Release\Net45</IntermediateOutputPath>
+    <OutputPath>bin\Release\Net46\</OutputPath>
+    <IntermediateOutputPath>obj\Release\Net46</IntermediateOutputPath>
     <DefineConstants>TRACE</DefineConstants>
     <ErrorReport>prompt</ErrorReport>
     <WarningLevel>4</WarningLevel>
@@ -78,7 +78,7 @@
   </ItemGroup>
   <ItemGroup>
     <Compile Include="..\CommonAssemblyInfo.cs" />
-    <Compile Include="Events_NET45.cs" />
+    <Compile Include="Events_NET46.cs" />
     <Compile Include="SingleAwaitSubject.cs" />
     <AppDesigner Include="Properties\" />
   </ItemGroup>
@@ -86,7 +86,7 @@
     <Service Include="{508349B6-6B84-4DF5-91F0-309BEEBAD82D}" />
   </ItemGroup>
   <ItemGroup>
-    <None Include="packages.ReactiveUI.Events_Net45.config">
+    <None Include="packages.ReactiveUI.Events_Net46.config">
       <SubType>Designer</SubType>
     </None>
   </ItemGroup>
diff --git a/src/ReactiveUI.Events/ReactiveUI.Events_Net45.sln b/src/ReactiveUI.Events/ReactiveUI.Events_Net46.sln
similarity index 93%
rename from src/ReactiveUI.Events/ReactiveUI.Events_Net45.sln
rename to src/ReactiveUI.Events/ReactiveUI.Events_Net46.sln
index 8713234be6..9ef8c28993 100644
--- a/src/ReactiveUI.Events/ReactiveUI.Events_Net45.sln
+++ b/src/ReactiveUI.Events/ReactiveUI.Events_Net46.sln
@@ -3,7 +3,7 @@ Microsoft Visual Studio Solution File, Format Version 12.00
 # Visual Studio 14
 VisualStudioVersion = 14.0.24720.0
 MinimumVisualStudioVersion = 10.0.40219.1
-Project("{FAE04EC0-301F-11D3-BF4B-00C04F79EFBC}") = "ReactiveUI.Events_Net45", "ReactiveUI.Events_Net45.csproj", "{600998C4-54DD-4755-BFA8-6F44544D8E2E}"
+Project("{FAE04EC0-301F-11D3-BF4B-00C04F79EFBC}") = "ReactiveUI.Events_Net46", "ReactiveUI.Events_Net46.csproj", "{600998C4-54DD-4755-BFA8-6F44544D8E2E}"
 EndProject
 Global
 	GlobalSection(SolutionConfigurationPlatforms) = preSolution
diff --git a/src/ReactiveUI.Events/packages.ReactiveUI.Events_Net45.config b/src/ReactiveUI.Events/packages.ReactiveUI.Events_Net46.config
similarity index 100%
rename from src/ReactiveUI.Events/packages.ReactiveUI.Events_Net45.config
rename to src/ReactiveUI.Events/packages.ReactiveUI.Events_Net46.config
diff --git a/src/ReactiveUI.Testing/ReactiveUI.Testing_Net45.csproj b/src/ReactiveUI.Testing/ReactiveUI.Testing_Net46.csproj
similarity index 89%
rename from src/ReactiveUI.Testing/ReactiveUI.Testing_Net45.csproj
rename to src/ReactiveUI.Testing/ReactiveUI.Testing_Net46.csproj
index b56cac74aa..e9172f3a03 100644
--- a/src/ReactiveUI.Testing/ReactiveUI.Testing_Net45.csproj
+++ b/src/ReactiveUI.Testing/ReactiveUI.Testing_Net46.csproj
@@ -10,7 +10,7 @@
     <AppDesignerFolder>Properties</AppDesignerFolder>
     <RootNamespace>ReactiveUI.Testing</RootNamespace>
     <AssemblyName>ReactiveUI.Testing</AssemblyName>
-    <TargetFrameworkVersion>v4.5</TargetFrameworkVersion>
+    <TargetFrameworkVersion>v4.6</TargetFrameworkVersion>
     <FileAlignment>512</FileAlignment>
     <SccProjectName>
     </SccProjectName>
@@ -27,9 +27,9 @@
     <DebugSymbols>true</DebugSymbols>
     <DebugType>full</DebugType>
     <Optimize>false</Optimize>
-    <OutputPath>bin\Debug\Net45\</OutputPath>
-    <IntermediateOutputPath>obj\Debug\Net45</IntermediateOutputPath>
-    <DefineConstants>DEBUG;TRACE;NET_45</DefineConstants>
+    <OutputPath>bin\Debug\Net46\</OutputPath>
+    <IntermediateOutputPath>obj\Debug\Net46</IntermediateOutputPath>
+    <DefineConstants>DEBUG;TRACE;NET_46</DefineConstants>
     <ErrorReport>prompt</ErrorReport>
     <WarningLevel>4</WarningLevel>
     <CodeAnalysisRuleSet>ExtendedCorrectnessRules.ruleset</CodeAnalysisRuleSet>
@@ -38,12 +38,12 @@
   <PropertyGroup Condition=" '$(Configuration)|$(Platform)' == 'Release|AnyCPU' ">
     <DebugType>pdbonly</DebugType>
     <Optimize>true</Optimize>
-    <OutputPath>bin\Release\Net45\</OutputPath>
-    <IntermediateOutputPath>obj\Release\Net45</IntermediateOutputPath>
-    <DefineConstants>TRACE;NET_45</DefineConstants>
+    <OutputPath>bin\Release\Net46\</OutputPath>
+    <IntermediateOutputPath>obj\Release\Net46</IntermediateOutputPath>
+    <DefineConstants>TRACE;NET_46</DefineConstants>
     <ErrorReport>prompt</ErrorReport>
     <WarningLevel>4</WarningLevel>
-    <DocumentationFile>bin\Release\Net45\ReactiveUI.Testing.xml</DocumentationFile>
+    <DocumentationFile>bin\Release\Net46\ReactiveUI.Testing.xml</DocumentationFile>
     <NoWarn>1591, 1573, 1711, 1587, 1570, 1572</NoWarn>
   </PropertyGroup>
   <ItemGroup>
@@ -96,13 +96,13 @@
     <Service Include="{508349B6-6B84-4DF5-91F0-309BEEBAD82D}" />
   </ItemGroup>
   <ItemGroup>
-    <ProjectReference Include="..\ReactiveUI\ReactiveUI_Net45.csproj">
+    <ProjectReference Include="..\ReactiveUI\ReactiveUI_Net46.csproj">
       <Project>{1ce2d235-8072-4649-ba5a-cfb1af8776e0}</Project>
-      <Name>ReactiveUI_Net45</Name>
+      <Name>ReactiveUI_Net46</Name>
     </ProjectReference>
   </ItemGroup>
   <ItemGroup>
-    <None Include="packages.ReactiveUI.Testing_Net45.config" />
+    <None Include="packages.ReactiveUI.Testing_Net46.config" />
   </ItemGroup>
   <Import Project="$(MSBuildToolsPath)\Microsoft.CSharp.targets" />
   <!-- To modify your build process, add your task inside one of the targets below and uncomment it. 
diff --git a/src/ReactiveUI.Testing/packages.ReactiveUI.Testing_Net45.config b/src/ReactiveUI.Testing/packages.ReactiveUI.Testing_Net46.config
similarity index 100%
rename from src/ReactiveUI.Testing/packages.ReactiveUI.Testing_Net45.config
rename to src/ReactiveUI.Testing/packages.ReactiveUI.Testing_Net46.config
diff --git a/src/ReactiveUI.Tests/ReactiveUI.Tests_Net45.csproj b/src/ReactiveUI.Tests/ReactiveUI.Tests_Net46.csproj
similarity index 91%
rename from src/ReactiveUI.Tests/ReactiveUI.Tests_Net45.csproj
rename to src/ReactiveUI.Tests/ReactiveUI.Tests_Net46.csproj
index 531e6db9e4..53c5368a21 100644
--- a/src/ReactiveUI.Tests/ReactiveUI.Tests_Net45.csproj
+++ b/src/ReactiveUI.Tests/ReactiveUI.Tests_Net46.csproj
@@ -1,5 +1,5 @@
 <?xml version="1.0" encoding="utf-8"?>
-<Project ToolsVersion="4.0" DefaultTargets="Build" xmlns="http://schemas.microsoft.com/developer/msbuild/2003">
+<Project ToolsVersion="12.0" DefaultTargets="Build" xmlns="http://schemas.microsoft.com/developer/msbuild/2003">
   <Import Project="..\packages\xunit.runner.visualstudio.2.2.0-beta1-build1144\build\net20\xunit.runner.visualstudio.props" Condition="Exists('..\packages\xunit.runner.visualstudio.2.2.0-beta1-build1144\build\net20\xunit.runner.visualstudio.props')" />
   <PropertyGroup>
     <Configuration Condition=" '$(Configuration)' == '' ">Debug</Configuration>
@@ -11,8 +11,8 @@
     <OutputType>Library</OutputType>
     <AppDesignerFolder>Properties</AppDesignerFolder>
     <RootNamespace>ReactiveUI.Tests</RootNamespace>
-    <AssemblyName>ReactiveUI.Tests_Net45</AssemblyName>
-    <TargetFrameworkVersion>v4.5</TargetFrameworkVersion>
+    <AssemblyName>ReactiveUI.Tests_Net46</AssemblyName>
+    <TargetFrameworkVersion>v4.6</TargetFrameworkVersion>
     <FileAlignment>512</FileAlignment>
     <ProjectTypeGuids>{FAE04EC0-301F-11D3-BF4B-00C04F79EFBC}</ProjectTypeGuids>
     <SolutionDir Condition="$(SolutionDir) == '' Or $(SolutionDir) == '*Undefined*'">..\</SolutionDir>
@@ -25,8 +25,8 @@
     <DebugSymbols>true</DebugSymbols>
     <DebugType>full</DebugType>
     <Optimize>false</Optimize>
-    <OutputPath>bin\Debug\Net45</OutputPath>
-    <IntermediateOutputPath>obj\Debug\Net45</IntermediateOutputPath>
+    <OutputPath>bin\Debug\Net46</OutputPath>
+    <IntermediateOutputPath>obj\Debug\Net46</IntermediateOutputPath>
     <DefineConstants>DEBUG;TRACE</DefineConstants>
     <ErrorReport>prompt</ErrorReport>
     <WarningLevel>4</WarningLevel>
@@ -35,8 +35,8 @@
   <PropertyGroup Condition=" '$(Configuration)|$(Platform)' == 'Release|AnyCPU' ">
     <DebugType>pdbonly</DebugType>
     <Optimize>true</Optimize>
-    <OutputPath>bin\Release\Net45</OutputPath>
-    <IntermediateOutputPath>obj\Release\Net45</IntermediateOutputPath>
+    <OutputPath>bin\Release\Net46</OutputPath>
+    <IntermediateOutputPath>obj\Release\Net46</IntermediateOutputPath>
     <DefineConstants>TRACE</DefineConstants>
     <ErrorReport>prompt</ErrorReport>
     <WarningLevel>4</WarningLevel>
@@ -137,21 +137,21 @@
     </Compile>
   </ItemGroup>
   <ItemGroup>
-    <ProjectReference Include="..\ReactiveUI.Blend\ReactiveUI.Blend_Net45.csproj">
+    <ProjectReference Include="..\ReactiveUI.Blend\ReactiveUI.Blend_Net46.csproj">
       <Project>{7866b5b1-5457-43a2-976a-e784eb10f2da}</Project>
-      <Name>ReactiveUI.Blend_Net45</Name>
+      <Name>ReactiveUI.Blend_Net46</Name>
     </ProjectReference>
-    <ProjectReference Include="..\ReactiveUI.Testing\ReactiveUI.Testing_Net45.csproj">
+    <ProjectReference Include="..\ReactiveUI.Testing\ReactiveUI.Testing_Net46.csproj">
       <Project>{dd99fd0f-82f6-4c30-930e-4a1d0df01d65}</Project>
-      <Name>ReactiveUI.Testing_Net45</Name>
+      <Name>ReactiveUI.Testing_Net46</Name>
     </ProjectReference>
-    <ProjectReference Include="..\ReactiveUI.Winforms\ReactiveUI.Winforms_Net45.csproj">
+    <ProjectReference Include="..\ReactiveUI.Winforms\ReactiveUI.Winforms_Net46.csproj">
       <Project>{f5ecbde5-e525-4482-b568-63217bcb0a0b}</Project>
-      <Name>ReactiveUI.Winforms_Net45</Name>
+      <Name>ReactiveUI.Winforms_Net46</Name>
     </ProjectReference>
-    <ProjectReference Include="..\ReactiveUI\ReactiveUI_Net45.csproj">
+    <ProjectReference Include="..\ReactiveUI\ReactiveUI_Net46.csproj">
       <Project>{1ce2d235-8072-4649-ba5a-cfb1af8776e0}</Project>
-      <Name>ReactiveUI_Net45</Name>
+      <Name>ReactiveUI_Net46</Name>
     </ProjectReference>
   </ItemGroup>
   <ItemGroup>
@@ -161,7 +161,7 @@
     <Service Include="{82A7F48D-3B50-4B1E-B82E-3ADA8210C358}" />
   </ItemGroup>
   <ItemGroup>
-    <None Include="packages.ReactiveUI.Tests_Net45.config" />
+    <None Include="packages.ReactiveUI.Tests_Net46.config" />
   </ItemGroup>
   <ItemGroup>
     <Page Include="Xaml\TestUserControl.xaml">
diff --git a/src/ReactiveUI.Tests/packages.ReactiveUI.Tests_Net45.config b/src/ReactiveUI.Tests/packages.ReactiveUI.Tests_Net46.config
similarity index 100%
rename from src/ReactiveUI.Tests/packages.ReactiveUI.Tests_Net45.config
rename to src/ReactiveUI.Tests/packages.ReactiveUI.Tests_Net46.config
diff --git a/src/ReactiveUI.Winforms/Properties/AssemblyInfo.cs b/src/ReactiveUI.Winforms/Properties/AssemblyInfo.cs
index 1723ee8257..8c500c803a 100644
--- a/src/ReactiveUI.Winforms/Properties/AssemblyInfo.cs
+++ b/src/ReactiveUI.Winforms/Properties/AssemblyInfo.cs
@@ -3,4 +3,4 @@
 using System.Runtime.CompilerServices;
 using System.Windows;
 
-[assembly: InternalsVisibleTo("ReactiveUI.Tests_Net45")]
+[assembly: InternalsVisibleTo("ReactiveUI.Tests_Net46")]
diff --git a/src/ReactiveUI.Winforms/ReactiveUI.Winforms_Net45.csproj b/src/ReactiveUI.Winforms/ReactiveUI.Winforms_Net46.csproj
similarity index 92%
rename from src/ReactiveUI.Winforms/ReactiveUI.Winforms_Net45.csproj
rename to src/ReactiveUI.Winforms/ReactiveUI.Winforms_Net46.csproj
index 09a2198732..8fbacfe393 100644
--- a/src/ReactiveUI.Winforms/ReactiveUI.Winforms_Net45.csproj
+++ b/src/ReactiveUI.Winforms/ReactiveUI.Winforms_Net46.csproj
@@ -10,7 +10,7 @@
     <AppDesignerFolder>Properties</AppDesignerFolder>
     <RootNamespace>ReactiveUI</RootNamespace>
     <AssemblyName>ReactiveUI.Winforms</AssemblyName>
-    <TargetFrameworkVersion>v4.5</TargetFrameworkVersion>
+    <TargetFrameworkVersion>v4.6</TargetFrameworkVersion>
     <FileAlignment>512</FileAlignment>
     <SccProjectName>
     </SccProjectName>
@@ -29,8 +29,8 @@
     <DebugSymbols>true</DebugSymbols>
     <DebugType>full</DebugType>
     <Optimize>false</Optimize>
-    <OutputPath>bin\Debug\Net45\</OutputPath>
-    <IntermediateOutputPath>obj\Debug\WinForms_Net45</IntermediateOutputPath>
+    <OutputPath>bin\Debug\Net46\</OutputPath>
+    <IntermediateOutputPath>obj\Debug\WinForms_Net46</IntermediateOutputPath>
     <DefineConstants>TRACE;DEBUG;WINFORMS</DefineConstants>
     <ErrorReport>prompt</ErrorReport>
     <WarningLevel>4</WarningLevel>
@@ -40,12 +40,12 @@
   <PropertyGroup Condition=" '$(Configuration)|$(Platform)' == 'Release|AnyCPU' ">
     <DebugType>pdbonly</DebugType>
     <Optimize>true</Optimize>
-    <OutputPath>bin\Release\Net45\</OutputPath>
-    <IntermediateOutputPath>obj\Release\Winforms_Net45\</IntermediateOutputPath>
+    <OutputPath>bin\Release\Net46\</OutputPath>
+    <IntermediateOutputPath>obj\Release\Winforms_Net46\</IntermediateOutputPath>
     <DefineConstants>TRACE;WINFORMS</DefineConstants>
     <ErrorReport>prompt</ErrorReport>
     <WarningLevel>4</WarningLevel>
-    <DocumentationFile>bin\Release\Net45\ReactiveUI.Winforms.xml</DocumentationFile>
+    <DocumentationFile>bin\Release\Net46\ReactiveUI.Winforms.xml</DocumentationFile>
     <NoWarn>1591, 1573, 1711, 1587, 1570, 1572</NoWarn>
   </PropertyGroup>
   <ItemGroup>
@@ -114,9 +114,9 @@
   </ItemGroup>
   <ItemGroup />
   <ItemGroup>
-    <ProjectReference Include="..\ReactiveUI\ReactiveUI_Net45.csproj">
+    <ProjectReference Include="..\ReactiveUI\ReactiveUI_Net46.csproj">
       <Project>{1ce2d235-8072-4649-ba5a-cfb1af8776e0}</Project>
-      <Name>ReactiveUI_Net45</Name>
+      <Name>ReactiveUI_Net46</Name>
     </ProjectReference>
   </ItemGroup>
   <Import Project="$(MSBuildToolsPath)\Microsoft.CSharp.targets" />
diff --git a/src/ReactiveUI.sln b/src/ReactiveUI.sln
index 053d294d2e..d124c0e1a8 100644
--- a/src/ReactiveUI.sln
+++ b/src/ReactiveUI.sln
@@ -12,7 +12,7 @@ Project("{2150E333-8FDC-42A3-9474-1A3956D46DE8}") = "Solution Items", "Solution
 EndProject
 Project("{FAE04EC0-301F-11D3-BF4B-00C04F79EFBC}") = "ReactiveUI", "ReactiveUI\ReactiveUI.csproj", "{464CB812-F99F-401B-BE4C-E8F0515CD19D}"
 EndProject
-Project("{FAE04EC0-301F-11D3-BF4B-00C04F79EFBC}") = "ReactiveUI.Blend_Net45", "ReactiveUI.Blend\ReactiveUI.Blend_Net45.csproj", "{7866B5B1-5457-43A2-976A-E784EB10F2DA}"
+Project("{FAE04EC0-301F-11D3-BF4B-00C04F79EFBC}") = "ReactiveUI.Blend_Net46", "ReactiveUI.Blend\ReactiveUI.Blend_Net46.csproj", "{7866B5B1-5457-43A2-976A-E784EB10F2DA}"
 EndProject
 Project("{FAE04EC0-301F-11D3-BF4B-00C04F79EFBC}") = "ReactiveUI.Blend_WinRT", "ReactiveUI.Blend\ReactiveUI.Blend_WinRT.csproj", "{14AE16FF-E9A7-4AB1-BCBB-3B2B2049288D}"
 EndProject
@@ -26,11 +26,11 @@ Project("{FAE04EC0-301F-11D3-BF4B-00C04F79EFBC}") = "ReactiveUI_Android", "React
 EndProject
 Project("{FAE04EC0-301F-11D3-BF4B-00C04F79EFBC}") = "ReactiveUI_iOS", "ReactiveUI\ReactiveUI_iOS.csproj", "{AF913370-A394-4DBD-801E-15E1FDA78FFC}"
 EndProject
-Project("{FAE04EC0-301F-11D3-BF4B-00C04F79EFBC}") = "ReactiveUI_Net45", "ReactiveUI\ReactiveUI_Net45.csproj", "{1CE2D235-8072-4649-BA5A-CFB1AF8776E0}"
+Project("{FAE04EC0-301F-11D3-BF4B-00C04F79EFBC}") = "ReactiveUI_Net46", "ReactiveUI\ReactiveUI_Net46.csproj", "{1CE2D235-8072-4649-BA5A-CFB1AF8776E0}"
 EndProject
 Project("{FAE04EC0-301F-11D3-BF4B-00C04F79EFBC}") = "ReactiveUI_WinRT", "ReactiveUI\ReactiveUI_WinRT.csproj", "{689EC7C5-2D81-4124-929E-397B330CC358}"
 EndProject
-Project("{FAE04EC0-301F-11D3-BF4B-00C04F79EFBC}") = "ReactiveUI.Winforms_Net45", "ReactiveUI.Winforms\ReactiveUI.Winforms_Net45.csproj", "{F5ECBDE5-E525-4482-B568-63217BCB0A0B}"
+Project("{FAE04EC0-301F-11D3-BF4B-00C04F79EFBC}") = "ReactiveUI.Winforms_Net46", "ReactiveUI.Winforms\ReactiveUI.Winforms_Net46.csproj", "{F5ECBDE5-E525-4482-B568-63217BCB0A0B}"
 EndProject
 Project("{FAE04EC0-301F-11D3-BF4B-00C04F79EFBC}") = "ReactiveUI_UWP", "ReactiveUI\ReactiveUI_UWP.csproj", "{128799C7-5776-401E-9E15-A9119C3D8318}"
 EndProject
@@ -42,13 +42,13 @@ Project("{FAE04EC0-301F-11D3-BF4B-00C04F79EFBC}") = "ReactiveUI.Testing_WinRT",
 EndProject
 Project("{FAE04EC0-301F-11D3-BF4B-00C04F79EFBC}") = "ReactiveUI.Testing_UWP", "ReactiveUI.Testing\ReactiveUI.Testing_UWP.csproj", "{F62056E2-C319-44BC-891F-6B1CDF57CC25}"
 EndProject
-Project("{FAE04EC0-301F-11D3-BF4B-00C04F79EFBC}") = "ReactiveUI.Testing_Net45", "ReactiveUI.Testing\ReactiveUI.Testing_Net45.csproj", "{DD99FD0F-82F6-4C30-930E-4A1D0DF01D65}"
+Project("{FAE04EC0-301F-11D3-BF4B-00C04F79EFBC}") = "ReactiveUI.Testing_Net46", "ReactiveUI.Testing\ReactiveUI.Testing_Net46.csproj", "{DD99FD0F-82F6-4C30-930E-4A1D0DF01D65}"
 EndProject
 Project("{FAE04EC0-301F-11D3-BF4B-00C04F79EFBC}") = "ReactiveUI.Testing_iOS", "ReactiveUI.Testing\ReactiveUI.Testing_iOS.csproj", "{9A913371-AE94-3DBD-8F1E-15E10DB72FFC}"
 EndProject
 Project("{FAE04EC0-301F-11D3-BF4B-00C04F79EFBC}") = "ReactiveUI.Testing_Android", "ReactiveUI.Testing\ReactiveUI.Testing_Android.csproj", "{1920477B-BB94-93CF-984E-E177EF9FEDB1}"
 EndProject
-Project("{FAE04EC0-301F-11D3-BF4B-00C04F79EFBC}") = "ReactiveUI.Tests_Net45", "ReactiveUI.Tests\ReactiveUI.Tests_Net45.csproj", "{6FBDE6EA-2202-4A70-8EE4-7BA6D515952E}"
+Project("{FAE04EC0-301F-11D3-BF4B-00C04F79EFBC}") = "ReactiveUI.Tests_Net46", "ReactiveUI.Tests\ReactiveUI.Tests_Net46.csproj", "{6FBDE6EA-2202-4A70-8EE4-7BA6D515952E}"
 EndProject
 Project("{FAE04EC0-301F-11D3-BF4B-00C04F79EFBC}") = "ReactiveUI_Mac", "ReactiveUI\ReactiveUI_Mac.csproj", "{1913BF79-061F-4667-ADF9-8E6CDA6D1211}"
 EndProject
diff --git a/src/ReactiveUI/Legacy/ReactiveCommand.cs b/src/ReactiveUI/Legacy/ReactiveCommand.cs
index bf39b07586..fe251f54a3 100755
--- a/src/ReactiveUI/Legacy/ReactiveCommand.cs
+++ b/src/ReactiveUI/Legacy/ReactiveCommand.cs
@@ -318,7 +318,7 @@ public static ReactiveCommand<object> CreateCombined(params IReactiveCommand[] c
     [Obsolete("This type is obsolete and will be removed in a future version of ReactiveUI. Please switch to using ReactiveUI.ReactiveCommand instead.")]
     public class ReactiveCommand<T> : IReactiveCommand<T>, IReactiveCommand
     {
-#if NET_45
+#if NET_46
         public event EventHandler CanExecuteChanged;
 
         protected virtual void raiseCanExecuteChanged(EventArgs args)
diff --git a/src/ReactiveUI/Properties/AssemblyInfo.cs b/src/ReactiveUI/Properties/AssemblyInfo.cs
index 28d9169d99..0a6867f8b4 100644
--- a/src/ReactiveUI/Properties/AssemblyInfo.cs
+++ b/src/ReactiveUI/Properties/AssemblyInfo.cs
@@ -3,7 +3,7 @@
 using System.Runtime.CompilerServices;
 using System.Windows;
 
-#if NET_45
+#if NET_46
 [assembly: ThemeInfo(
    ResourceDictionaryLocation.None, //where theme specific resource dictionaries are located
                                     //(used if a resource is not found in the page, 
@@ -14,7 +14,7 @@
 )]
 #endif
 
-[assembly: InternalsVisibleTo("ReactiveUI.Tests_Net45")]
+[assembly: InternalsVisibleTo("ReactiveUI.Tests_Net46")]
 [assembly: InternalsVisibleTo("ReactiveUI.Tests_WinRT")]
 [assembly: InternalsVisibleTo("ReactiveUI_Tests_iOS")] // NB: iOS apps can't have '.' in the name
 [assembly: InternalsVisibleTo("ReactiveUI.Tests_Android")]
diff --git a/src/ReactiveUI/ReactiveList.cs b/src/ReactiveUI/ReactiveList.cs
index 225935136a..aa7c8f9745 100644
--- a/src/ReactiveUI/ReactiveList.cs
+++ b/src/ReactiveUI/ReactiveList.cs
@@ -23,7 +23,7 @@ namespace ReactiveUI
     [DebuggerTypeProxy(typeof(CollectionDebugView<>))]
     public class ReactiveList<T> : IReactiveList<T>, IReadOnlyReactiveList<T>, IList
     {
-#if NET_45
+#if NET_46
         public event NotifyCollectionChangedEventHandler CollectionChanging;
 
         protected virtual void raiseCollectionChanging(NotifyCollectionChangedEventArgs args)
diff --git a/src/ReactiveUI/ReactiveObject.cs b/src/ReactiveUI/ReactiveObject.cs
index 291d923403..2131a37ff3 100644
--- a/src/ReactiveUI/ReactiveObject.cs
+++ b/src/ReactiveUI/ReactiveObject.cs
@@ -24,7 +24,7 @@ namespace ReactiveUI
     [DataContract]
     public class ReactiveObject : IReactiveNotifyPropertyChanged<IReactiveObject>, IHandleObservableErrors, IReactiveObject
     {
-#if NET_45        
+#if NET_46        
         public event PropertyChangingEventHandler PropertyChanging;
 
         void IReactiveObject.RaisePropertyChanging(PropertyChangingEventArgs args)
diff --git a/src/ReactiveUI/ReactiveUI_Net45.csproj b/src/ReactiveUI/ReactiveUI_Net46.csproj
similarity index 92%
rename from src/ReactiveUI/ReactiveUI_Net45.csproj
rename to src/ReactiveUI/ReactiveUI_Net46.csproj
index 660375998c..c1c1866797 100644
--- a/src/ReactiveUI/ReactiveUI_Net45.csproj
+++ b/src/ReactiveUI/ReactiveUI_Net46.csproj
@@ -1,5 +1,5 @@
 <?xml version="1.0" encoding="utf-8"?>
-<Project ToolsVersion="4.0" DefaultTargets="Build" xmlns="http://schemas.microsoft.com/developer/msbuild/2003">
+<Project ToolsVersion="12.0" DefaultTargets="Build" xmlns="http://schemas.microsoft.com/developer/msbuild/2003">
   <PropertyGroup>
     <Configuration Condition=" '$(Configuration)' == '' ">Debug</Configuration>
     <Platform Condition=" '$(Platform)' == '' ">AnyCPU</Platform>
@@ -10,20 +10,21 @@
     <AppDesignerFolder>Properties</AppDesignerFolder>
     <RootNamespace>ReactiveUI</RootNamespace>
     <AssemblyName>ReactiveUI</AssemblyName>
-    <TargetFrameworkVersion>v4.5</TargetFrameworkVersion>
+    <TargetFrameworkVersion>v4.6</TargetFrameworkVersion>
     <FileAlignment>512</FileAlignment>
     <Utf8Output>true</Utf8Output>
     <ExpressionBlendVersion>4.0.30816.0</ExpressionBlendVersion>
     <SolutionDir Condition="$(SolutionDir) == '' Or $(SolutionDir) == '*Undefined*'">..\</SolutionDir>
     <RestorePackages>true</RestorePackages>
+    <TargetFrameworkProfile />
   </PropertyGroup>
   <PropertyGroup Condition=" '$(Configuration)|$(Platform)' == 'Debug|AnyCPU' ">
     <DebugSymbols>true</DebugSymbols>
     <DebugType>full</DebugType>
     <Optimize>false</Optimize>
-    <OutputPath>bin\Debug\Net45\</OutputPath>
-    <IntermediateOutputPath>obj\Debug\Net45</IntermediateOutputPath>
-    <DefineConstants>TRACE;DEBUG;NET_45; XAML</DefineConstants>
+    <OutputPath>bin\Debug\Net46\</OutputPath>
+    <IntermediateOutputPath>obj\Debug\Net46</IntermediateOutputPath>
+    <DefineConstants>TRACE;DEBUG;NET_46; XAML</DefineConstants>
     <ErrorReport>prompt</ErrorReport>
     <WarningLevel>4</WarningLevel>
     <CodeAnalysisRuleSet>ExtendedCorrectnessRules.ruleset</CodeAnalysisRuleSet>
@@ -32,12 +33,12 @@
   <PropertyGroup Condition=" '$(Configuration)|$(Platform)' == 'Release|AnyCPU' ">
     <DebugType>pdbonly</DebugType>
     <Optimize>true</Optimize>
-    <OutputPath>bin\Release\Net45\</OutputPath>
-    <IntermediateOutputPath>bin\Release\Net45</IntermediateOutputPath>
-    <DefineConstants>TRACE;NET_45; XAML</DefineConstants>
+    <OutputPath>bin\Release\Net46\</OutputPath>
+    <IntermediateOutputPath>bin\Release\Net46</IntermediateOutputPath>
+    <DefineConstants>TRACE;NET_46; XAML</DefineConstants>
     <ErrorReport>prompt</ErrorReport>
     <WarningLevel>4</WarningLevel>
-    <DocumentationFile>bin\Release\Net45\ReactiveUI.xml</DocumentationFile>
+    <DocumentationFile>bin\Release\Net46\ReactiveUI.xml</DocumentationFile>
     <NoWarn>1591, 1573, 1711, 1587, 1570, 1572</NoWarn>
   </PropertyGroup>
   <ItemGroup>
@@ -164,7 +165,7 @@
     <Service Include="{508349B6-6B84-4DF5-91F0-309BEEBAD82D}" />
   </ItemGroup>
   <ItemGroup>
-    <None Include="packages.ReactiveUI_Net45.config" />
+    <None Include="packages.ReactiveUI_Net46.config" />
   </ItemGroup>
   <Import Project="$(MSBuildToolsPath)\Microsoft.CSharp.targets" />
   <!-- To modify your build process, add your task inside one of the targets below and uncomment it. 
diff --git a/src/ReactiveUI/WeakEventManager.cs b/src/ReactiveUI/WeakEventManager.cs
index ebe2c81d1b..28ab8af001 100644
--- a/src/ReactiveUI/WeakEventManager.cs
+++ b/src/ReactiveUI/WeakEventManager.cs
@@ -13,7 +13,7 @@
 
 namespace ReactiveUI
 {
-#if !NET_45
+#if !NET_46
     internal class CanExecuteChangedEventManager : WeakEventManager<ICommand, EventHandler, EventArgs>
     {
     }
diff --git a/src/ReactiveUI/packages.ReactiveUI_Net45.config b/src/ReactiveUI/packages.ReactiveUI_Net46.config
similarity index 100%
rename from src/ReactiveUI/packages.ReactiveUI_Net45.config
rename to src/ReactiveUI/packages.ReactiveUI_Net46.config