diff --git a/src/ReactiveUI.Tests/Platforms/wpf/Mocks/WpfTestWindow.cs b/src/ReactiveUI.Tests/Platforms/wpf/Mocks/WpfTestWindow.cs
new file mode 100644
index 0000000000..0807b676c7
--- /dev/null
+++ b/src/ReactiveUI.Tests/Platforms/wpf/Mocks/WpfTestWindow.cs
@@ -0,0 +1,22 @@
+// Copyright (c) 2021 .NET Foundation and Contributors. All rights reserved.
+// Licensed to the .NET Foundation under one or more agreements.
+// The .NET Foundation licenses this file to you under the MIT license.
+// See the LICENSE file in the project root for full license information.
+
+using System.Windows;
+using System.Windows.Controls;
+
+namespace ReactiveUI.Tests.Wpf
+{
+    public class WpfTestWindow : Window, IActivatableView
+    {
+        public WpfTestWindow()
+        {
+            RootGrid = new Grid();
+
+            AddChild(RootGrid);
+        }
+
+        public Grid RootGrid { get; }
+    }
+}
diff --git a/src/ReactiveUI.Tests/Platforms/wpf/WpfActivationForViewFetcherTest.cs b/src/ReactiveUI.Tests/Platforms/wpf/WpfActivationForViewFetcherTest.cs
index 9faaadd414..d430aacdf2 100644
--- a/src/ReactiveUI.Tests/Platforms/wpf/WpfActivationForViewFetcherTest.cs
+++ b/src/ReactiveUI.Tests/Platforms/wpf/WpfActivationForViewFetcherTest.cs
@@ -1,130 +1,182 @@
-// Copyright (c) 2021 .NET Foundation and Contributors. All rights reserved.
-// Licensed to the .NET Foundation under one or more agreements.
-// The .NET Foundation licenses this file to you under the MIT license.
-// See the LICENSE file in the project root for full license information.
-
-using System;
-using System.Reactive.Concurrency;
-using System.Windows;
-
-using DynamicData;
-using Xunit;
-
-using FactAttribute = Xunit.WpfFactAttribute;
-
-namespace ReactiveUI.Tests.Wpf
-{
-    public class WpfActivationForViewFetcherTest
-    {
-        [Fact]
-        public void FrameworkElementIsActivatedAndDeactivated()
-        {
-            var uc = new WpfTestUserControl();
-            var activation = new ActivationForViewFetcher();
-
-            var obs = activation.GetActivationForView(uc);
-            obs.ToObservableChangeSet(scheduler: ImmediateScheduler.Instance).Bind(out var activated).Subscribe();
-
-            var loaded = new RoutedEventArgs();
-            loaded.RoutedEvent = FrameworkElement.LoadedEvent;
-
-            uc.RaiseEvent(loaded);
-
-            new[] { true }.AssertAreEqual(activated);
-
-            var unloaded = new RoutedEventArgs();
-            unloaded.RoutedEvent = FrameworkElement.UnloadedEvent;
-
-            uc.RaiseEvent(unloaded);
-
-            new[] { true, false }.AssertAreEqual(activated);
-        }
-
-        [Fact]
-        public void IsHitTestVisibleActivatesFrameworkElement()
-        {
-            var uc = new WpfTestUserControl();
-            uc.IsHitTestVisible = false;
-            var activation = new ActivationForViewFetcher();
-
-            var obs = activation.GetActivationForView(uc);
-            obs.ToObservableChangeSet(scheduler: ImmediateScheduler.Instance).Bind(out var activated).Subscribe();
-
-            var loaded = new RoutedEventArgs();
-            loaded.RoutedEvent = FrameworkElement.LoadedEvent;
-
-            uc.RaiseEvent(loaded);
-
-            // Loaded has happened.
-            new[] { true }.AssertAreEqual(activated);
-
-            uc.IsHitTestVisible = true;
-
-            // IsHitTestVisible true, we don't want the event to repeat unnecessarily.
-            new[] { true }.AssertAreEqual(activated);
-
-            var unloaded = new RoutedEventArgs();
-            unloaded.RoutedEvent = FrameworkElement.UnloadedEvent;
-
-            uc.RaiseEvent(unloaded);
-
-            // We had both a loaded/hit test visible change/unloaded happen.
-            new[] { true, false }.AssertAreEqual(activated);
-        }
-
-        [Fact]
-        public void IsHitTestVisibleDeactivatesFrameworkElement()
-        {
-            var uc = new WpfTestUserControl();
-            var activation = new ActivationForViewFetcher();
-
-            var obs = activation.GetActivationForView(uc);
-            obs.ToObservableChangeSet(scheduler: ImmediateScheduler.Instance).Bind(out var activated).Subscribe();
-
-            var loaded = new RoutedEventArgs();
-            loaded.RoutedEvent = FrameworkElement.LoadedEvent;
-
-            uc.RaiseEvent(loaded);
-
-            new[] { true }.AssertAreEqual(activated);
-
-            uc.IsHitTestVisible = false;
-
-            new[] { true, false }.AssertAreEqual(activated);
-        }
-
-        [Fact]
-        public void FrameworkElementIsActivatedAndDeactivatedWithHitTest()
-        {
-            var uc = new WpfTestUserControl();
-            var activation = new ActivationForViewFetcher();
-
-            var obs = activation.GetActivationForView(uc);
-            obs.ToObservableChangeSet(scheduler: ImmediateScheduler.Instance).Bind(out var activated).Subscribe();
-
-            var loaded = new RoutedEventArgs();
-            loaded.RoutedEvent = FrameworkElement.LoadedEvent;
-
-            uc.RaiseEvent(loaded);
-
-            new[] { true }.AssertAreEqual(activated);
-
-            // this should deactivate it
-            uc.IsHitTestVisible = false;
-
-            new[] { true, false }.AssertAreEqual(activated);
-
-            // this should activate it
-            uc.IsHitTestVisible = true;
-
-            new[] { true, false, true }.AssertAreEqual(activated);
-
-            var unloaded = new RoutedEventArgs();
-            unloaded.RoutedEvent = FrameworkElement.UnloadedEvent;
-
-            uc.RaiseEvent(unloaded);
-
-            new[] { true, false, true, false }.AssertAreEqual(activated);
-        }
-    }
-}
+// Copyright (c) 2021 .NET Foundation and Contributors. All rights reserved.
+// Licensed to the .NET Foundation under one or more agreements.
+// The .NET Foundation licenses this file to you under the MIT license.
+// See the LICENSE file in the project root for full license information.
+
+using System;
+using System.Reactive.Concurrency;
+using System.Windows;
+
+using DynamicData;
+using Xunit;
+
+using FactAttribute = Xunit.WpfFactAttribute;
+
+namespace ReactiveUI.Tests.Wpf
+{
+    public class WpfActivationForViewFetcherTest
+    {
+        [Fact]
+        public void FrameworkElementIsActivatedAndDeactivated()
+        {
+            var uc = new WpfTestUserControl();
+            var activation = new ActivationForViewFetcher();
+
+            var obs = activation.GetActivationForView(uc);
+            obs.ToObservableChangeSet(scheduler: ImmediateScheduler.Instance).Bind(out var activated).Subscribe();
+
+            var loaded = new RoutedEventArgs();
+            loaded.RoutedEvent = FrameworkElement.LoadedEvent;
+
+            uc.RaiseEvent(loaded);
+
+            new[] { true }.AssertAreEqual(activated);
+
+            var unloaded = new RoutedEventArgs();
+            unloaded.RoutedEvent = FrameworkElement.UnloadedEvent;
+
+            uc.RaiseEvent(unloaded);
+
+            new[] { true, false }.AssertAreEqual(activated);
+        }
+
+        [Fact]
+        public void WindowIsActivatedAndDeactivated()
+        {
+            var window = new WpfTestWindow();
+            var activation = new ActivationForViewFetcher();
+
+            var obs = activation.GetActivationForView(window);
+            obs.ToObservableChangeSet(scheduler: ImmediateScheduler.Instance).Bind(out var activated).Subscribe();
+
+            var loaded = new RoutedEventArgs();
+            loaded.RoutedEvent = FrameworkElement.LoadedEvent;
+
+            window.RaiseEvent(loaded);
+
+            new[] { true }.AssertAreEqual(activated);
+
+            window.Close();
+
+            new[] { true, false }.AssertAreEqual(activated);
+        }
+
+        [StaFact]
+        public void WindowAndFrameworkElementAreActivatedAndDeactivated()
+        {
+            var window = new WpfTestWindow();
+            var uc = new WpfTestUserControl();
+
+            window.RootGrid.Children.Add(uc);
+
+            var activation = new ActivationForViewFetcher();
+
+            var windowObs = activation.GetActivationForView(window);
+            windowObs.ToObservableChangeSet(scheduler: ImmediateScheduler.Instance).Bind(out var windowActivated).Subscribe();
+
+            var ucObs = activation.GetActivationForView(uc);
+            ucObs.ToObservableChangeSet(scheduler: ImmediateScheduler.Instance).Bind(out var controlActivated).Subscribe();
+
+            var loaded = new RoutedEventArgs();
+            loaded.RoutedEvent = FrameworkElement.LoadedEvent;
+
+            window.RaiseEvent(loaded);
+            uc.RaiseEvent(loaded);
+
+            new[] { true }.AssertAreEqual(windowActivated);
+            new[] { true }.AssertAreEqual(controlActivated);
+
+            window.Dispatcher.InvokeShutdown();
+
+            new[] { true, false }.AssertAreEqual(windowActivated);
+            new[] { true, false }.AssertAreEqual(controlActivated);
+        }
+
+        [Fact]
+        public void IsHitTestVisibleActivatesFrameworkElement()
+        {
+            var uc = new WpfTestUserControl();
+            uc.IsHitTestVisible = false;
+            var activation = new ActivationForViewFetcher();
+
+            var obs = activation.GetActivationForView(uc);
+            obs.ToObservableChangeSet(scheduler: ImmediateScheduler.Instance).Bind(out var activated).Subscribe();
+
+            var loaded = new RoutedEventArgs();
+            loaded.RoutedEvent = FrameworkElement.LoadedEvent;
+
+            uc.RaiseEvent(loaded);
+
+            // Loaded has happened.
+            new[] { true }.AssertAreEqual(activated);
+
+            uc.IsHitTestVisible = true;
+
+            // IsHitTestVisible true, we don't want the event to repeat unnecessarily.
+            new[] { true }.AssertAreEqual(activated);
+
+            var unloaded = new RoutedEventArgs();
+            unloaded.RoutedEvent = FrameworkElement.UnloadedEvent;
+
+            uc.RaiseEvent(unloaded);
+
+            // We had both a loaded/hit test visible change/unloaded happen.
+            new[] { true, false }.AssertAreEqual(activated);
+        }
+
+        [Fact]
+        public void IsHitTestVisibleDeactivatesFrameworkElement()
+        {
+            var uc = new WpfTestUserControl();
+            var activation = new ActivationForViewFetcher();
+
+            var obs = activation.GetActivationForView(uc);
+            obs.ToObservableChangeSet(scheduler: ImmediateScheduler.Instance).Bind(out var activated).Subscribe();
+
+            var loaded = new RoutedEventArgs();
+            loaded.RoutedEvent = FrameworkElement.LoadedEvent;
+
+            uc.RaiseEvent(loaded);
+
+            new[] { true }.AssertAreEqual(activated);
+
+            uc.IsHitTestVisible = false;
+
+            new[] { true, false }.AssertAreEqual(activated);
+        }
+
+        [Fact]
+        public void FrameworkElementIsActivatedAndDeactivatedWithHitTest()
+        {
+            var uc = new WpfTestUserControl();
+            var activation = new ActivationForViewFetcher();
+
+            var obs = activation.GetActivationForView(uc);
+            obs.ToObservableChangeSet(scheduler: ImmediateScheduler.Instance).Bind(out var activated).Subscribe();
+
+            var loaded = new RoutedEventArgs();
+            loaded.RoutedEvent = FrameworkElement.LoadedEvent;
+
+            uc.RaiseEvent(loaded);
+
+            new[] { true }.AssertAreEqual(activated);
+
+            // this should deactivate it
+            uc.IsHitTestVisible = false;
+
+            new[] { true, false }.AssertAreEqual(activated);
+
+            // this should activate it
+            uc.IsHitTestVisible = true;
+
+            new[] { true, false, true }.AssertAreEqual(activated);
+
+            var unloaded = new RoutedEventArgs();
+            unloaded.RoutedEvent = FrameworkElement.UnloadedEvent;
+
+            uc.RaiseEvent(unloaded);
+
+            new[] { true, false, true, false }.AssertAreEqual(activated);
+        }
+    }
+}
diff --git a/src/ReactiveUI.Wpf/ActivationForViewFetcher.cs b/src/ReactiveUI.Wpf/ActivationForViewFetcher.cs
index c42f730ec8..b07cff5592 100644
--- a/src/ReactiveUI.Wpf/ActivationForViewFetcher.cs
+++ b/src/ReactiveUI.Wpf/ActivationForViewFetcher.cs
@@ -7,6 +7,7 @@
 using System.Reactive.Linq;
 using System.Reflection;
 using System.Windows;
+using System.Windows.Threading;
 
 namespace ReactiveUI
 {
@@ -55,10 +56,49 @@ public IObservable<bool> GetActivationForView(IActivatableView view)
                 x => fe.Unloaded += x,
                 x => fe.Unloaded -= x);
 
+            var windowActivation = GetActivationForWindow(view);
+
+            var dispatcherActivation = GetActivationForDispatcher(fe);
+
             return viewLoaded
                 .Merge(viewUnloaded)
                 .Merge(hitTestVisible)
+                .Merge(windowActivation)
+                .Merge(dispatcherActivation)
                 .DistinctUntilChanged();
         }
+
+        private static IObservable<bool> GetActivationForWindow(IActivatableView view)
+        {
+            if (view is not Window window)
+            {
+                return Observable<bool>.Empty;
+            }
+
+            var viewClosed = Observable.FromEvent<EventHandler, bool>(
+                eventHandler =>
+                {
+                    void Handler(object? sender, EventArgs e) => eventHandler(false);
+                    return Handler;
+                },
+                x => window.Closed += x,
+                x => window.Closed -= x);
+
+            return viewClosed;
+        }
+
+        private static IObservable<bool> GetActivationForDispatcher(DispatcherObject dispatcherObject)
+        {
+            var dispatcherShutdownStarted = Observable.FromEvent<EventHandler, bool>(
+                eventHandler =>
+                {
+                    void Handler(object? sender, EventArgs e) => eventHandler(false);
+                    return Handler;
+                },
+                x => dispatcherObject.Dispatcher.ShutdownStarted += x,
+                x => dispatcherObject.Dispatcher.ShutdownStarted -= x);
+
+            return dispatcherShutdownStarted;
+        }
     }
 }