diff --git a/rules-tests/Php72/Rector/While_/WhileEachToForeachRector/Fixture/trailing_comma_last.php.inc b/rules-tests/Php72/Rector/While_/WhileEachToForeachRector/Fixture/trailing_comma_last.php.inc
new file mode 100644
index 00000000000..69955633cc6
--- /dev/null
+++ b/rules-tests/Php72/Rector/While_/WhileEachToForeachRector/Fixture/trailing_comma_last.php.inc
@@ -0,0 +1,34 @@
+<?php
+
+namespace Rector\Tests\Php72\Rector\While_\WhileEachToForeachRector\Fixture;
+
+// ref https://3v4l.org/mTeIL#v7.1.31 vs https://3v4l.org/UJH9S
+final class TrailingCommaLast
+{
+    public function run()
+    {
+        while(list($code_name,) = each($poster_xd))
+        {
+            $poster_xd[$code_name] = preg_replace($orig_word, $replacement_word, $poster_xd[$code_name]);
+        }
+    }
+}
+
+?>
+-----
+<?php
+
+namespace Rector\Tests\Php72\Rector\While_\WhileEachToForeachRector\Fixture;
+
+// ref https://3v4l.org/mTeIL#v7.1.31 vs https://3v4l.org/UJH9S
+final class TrailingCommaLast
+{
+    public function run()
+    {
+        foreach (array_keys($poster_xd) as $code_name) {
+            $poster_xd[$code_name] = preg_replace($orig_word, $replacement_word, $poster_xd[$code_name]);
+        }
+    }
+}
+
+?>
diff --git a/rules/Php72/Rector/While_/WhileEachToForeachRector.php b/rules/Php72/Rector/While_/WhileEachToForeachRector.php
index 44564a6ddd8..42340f5b0fd 100644
--- a/rules/Php72/Rector/While_/WhileEachToForeachRector.php
+++ b/rules/Php72/Rector/While_/WhileEachToForeachRector.php
@@ -113,8 +113,16 @@ public function refactor(Node $node): ?Node
             [$eachFuncCall->args[0]]
         ) : $eachFuncCall->args[0]->value;
 
-        /** @var ArrayItem $arrayItem */
         $arrayItem = array_pop($listNode->items);
+        $isTrailingCommaLast = false;
+        if (! $arrayItem instanceof ArrayItem) {
+            $foreachedExpr = $this->nodeFactory->createFuncCall('array_keys', [$eachFuncCall->args[0]]);
+            /** @var ArrayItem $arrayItem */
+            $arrayItem = current($listNode->items);
+
+            $isTrailingCommaLast = true;
+        }
+
         $foreach = new Foreach_($foreachedExpr, $arrayItem, [
             'stmts' => $node->stmts,
         ]);
@@ -126,7 +134,7 @@ public function refactor(Node $node): ?Node
             /** @var ArrayItem|null $keyItem */
             $keyItem = array_pop($listNode->items);
 
-            if ($keyItem !== null) {
+            if ($keyItem !== null && ! $isTrailingCommaLast) {
                 $foreach->keyVar = $keyItem->value;
             }
         }