diff --git a/lib/modules/manager/regex/readme.md b/lib/modules/manager/regex/readme.md
index 44086feed2d896..5d1632f43b04c1 100644
--- a/lib/modules/manager/regex/readme.md
+++ b/lib/modules/manager/regex/readme.md
@@ -51,6 +51,9 @@ If you're looking for an online regex testing tool that supports capture groups,
 Be aware that backslashes (`'\'`) of the resulting regex have to still be escaped e.g. `\n\s` --> `\\n\\s`.
 You can use the Code Generator in the sidebar and copy the regex in the generated "Alternative syntax" comment into JSON.
 
+The `regex` manager uses [RE2](https://github.com/google/re2/wiki/WhyRE2) which does not support [backreferences and lookahead assertions](https://github.com/uhop/node-re2#limitations-things-re2-does-not-support).
+The `regex` manager matches are done per-file and not per-line, you should be aware when using the `^` and/or `$` regex assertions.
+
 ### Configuration templates
 
 In many cases, named capture groups alone won't be enough and you'll need to configure Renovate with additional information about how to look up a dependency.