diff --git a/.github/workflows/ci.yml b/.github/workflows/ci.yml
index 04373c7c..5b046c4d 100644
--- a/.github/workflows/ci.yml
+++ b/.github/workflows/ci.yml
@@ -9,10 +9,10 @@ on:
 
 jobs:
   build:
-    runs-on: ubuntu-18.04
+    runs-on: ubuntu-20.04
     strategy:
       matrix:
-        python-version: [2.7, 3.4, 3.5, 3.6, 3.7, 3.8, 3.9, '3.10', 3.11]
+        python-version: [3.5, 3.6, 3.7, 3.8, 3.9, '3.10', 3.11]
         framework:
           - FLASK_VERSION=0.12.5 Werkzeug\>=0.7,\<1.0
           - FLASK_VERSION=1.1.4
@@ -22,7 +22,6 @@ jobs:
           - DJANGO_VERSION=3.2.18
           - DJANGO_VERSION=4.0.10
           - DJANGO_VERSION=4.1.7
-          - TWISTED_VERSION=17.1.0 treq==16.12.0 zope.interface==4.5.0
           - TWISTED_VERSION=20.3.0
           - TWISTED_VERSION=21.7.0
           - TWISTED_VERSION=22.10.0
@@ -35,12 +34,6 @@ jobs:
         exclude:
           # Test frameworks on the python versions they support, according to pypi registry
           # Flask
-          - framework: FLASK_VERSION=1.1.4
-            python-version: 3.4
-          - framework: FLASK_VERSION=2.2.3
-            python-version: 2.7
-          - framework: FLASK_VERSION=2.2.3
-            python-version: 3.4
           - framework: FLASK_VERSION=2.2.3
             python-version: 3.5
           - framework: FLASK_VERSION=2.2.3
@@ -55,108 +48,43 @@ jobs:
             python-version: '3.10'
           - framework: DJANGO_VERSION=1.11.29
             python-version: 3.11
-          - framework: DJANGO_VERSION=2.2.28
-            python-version: 2.7
-          - framework: DJANGO_VERSION=2.2.28
-            python-version: 3.4
-          - framework: DJANGO_VERSION=3.2.18
-            python-version: 2.7
-          - framework: DJANGO_VERSION=3.2.18
-            python-version: 3.4
           - framework: DJANGO_VERSION=3.2.18
             python-version: 3.5
-          - framework: DJANGO_VERSION=4.0.10
-            python-version: 2.7
-          - framework: DJANGO_VERSION=4.0.10
-            python-version: 3.4
           - framework: DJANGO_VERSION=4.0.10
             python-version: 3.5
           - framework: DJANGO_VERSION=4.0.10
             python-version: 3.6
           - framework: DJANGO_VERSION=4.0.10
             python-version: 3.7
-          - framework: DJANGO_VERSION=4.1.7
-            python-version: 2.7
-          - framework: DJANGO_VERSION=4.1.7
-            python-version: 3.4
           - framework: DJANGO_VERSION=4.1.7
             python-version: 3.5
           - framework: DJANGO_VERSION=4.1.7
             python-version: 3.6
           - framework: DJANGO_VERSION=4.1.7
             python-version: 3.7
-          
+
           # Twisted
-          - framework: TWISTED_VERSION=17.1.0 treq==16.12.0 zope.interface==4.5.0
-            python-version: 3.4
-          - framework: TWISTED_VERSION=17.1.0 treq==16.12.0 zope.interface==4.5.0
-            python-version: 3.5
-          - framework: TWISTED_VERSION=17.1.0 treq==16.12.0 zope.interface==4.5.0
-            python-version: 3.6
-          - framework: TWISTED_VERSION=17.1.0 treq==16.12.0 zope.interface==4.5.0
-            python-version: 3.7
-          - framework: TWISTED_VERSION=17.1.0 treq==16.12.0 zope.interface==4.5.0
-            python-version: 3.8
-          - framework: TWISTED_VERSION=17.1.0 treq==16.12.0 zope.interface==4.5.0
-            python-version: 3.9
-          - framework: TWISTED_VERSION=17.1.0 treq==16.12.0 zope.interface==4.5.0
-            python-version: '3.10'
-          - framework: TWISTED_VERSION=17.1.0 treq==16.12.0 zope.interface==4.5.0
-            python-version: 3.11
-          - framework: TWISTED_VERSION=20.3.0
-            python-version: 2.7
-          - framework: TWISTED_VERSION=20.3.0
-            python-version: 3.4
           - framework: TWISTED_VERSION=20.3.0
             python-version: 3.11
-          - framework: TWISTED_VERSION=21.7.0
-            python-version: 2.7
-          - framework: TWISTED_VERSION=21.7.0
-            python-version: 3.4
           - framework: TWISTED_VERSION=21.7.0
             python-version: 3.5
-          - framework: TWISTED_VERSION=22.10.0
-            python-version: 2.7
-          - framework: TWISTED_VERSION=22.10.0
-            python-version: 3.4
           - framework: TWISTED_VERSION=22.10.0
             python-version: 3.5
           - framework: TWISTED_VERSION=22.10.0
             python-version: 3.6
 
-          
+
           # Starlette
-          - framework: STARLETTE_VERSION=0.12.13 httpx==0.18.1 python-multipart==0.0.5
-            python-version: 2.7
-          - framework: STARLETTE_VERSION=0.12.13 httpx==0.18.1 python-multipart==0.0.5
-            python-version: 3.4
           - framework: STARLETTE_VERSION=0.12.13 httpx==0.18.1 python-multipart==0.0.5
             python-version: 3.5
-          - framework: STARLETTE_VERSION=0.14.2 httpx==0.18.1 python-multipart==0.0.5
-            python-version: 2.7
-          - framework: STARLETTE_VERSION=0.14.2 httpx==0.18.1 python-multipart==0.0.5
-            python-version: 3.4
           - framework: STARLETTE_VERSION=0.14.2 httpx==0.18.1 python-multipart==0.0.5
             python-version: 3.5
-          
+
           # Fastapi
-          - framework: FASTAPI_VERSION=0.40.0 httpx==0.18.1 python-multipart==0.0.5
-            python-version: 2.7
-          - framework: FASTAPI_VERSION=0.40.0 httpx==0.18.1 python-multipart==0.0.5
-            python-version: 3.4
           - framework: FASTAPI_VERSION=0.40.0 httpx==0.18.1 python-multipart==0.0.5
             python-version: 3.5
-          - framework: FASTAPI_VERSION=0.50.0 httpx==0.18.1 python-multipart==0.0.5
-            python-version: 2.7
-          - framework: FASTAPI_VERSION=0.50.0 httpx==0.18.1 python-multipart==0.0.5
-            python-version: 3.4
           - framework: FASTAPI_VERSION=0.50.0 httpx==0.18.1 python-multipart==0.0.5
             python-version: 3.5
-          
-          - framework: FASTAPI_VERSION=0.63.0 httpx==0.18.1 python-multipart==0.0.5
-            python-version: 2.7
-          - framework: FASTAPI_VERSION=0.63.0 httpx==0.18.1 python-multipart==0.0.5
-            python-version: 3.4
           - framework: FASTAPI_VERSION=0.63.0 httpx==0.18.1 python-multipart==0.0.5
             python-version: 3.5
 
@@ -170,21 +98,6 @@ jobs:
         with:
           python-version: ${{ matrix.python-version }}
 
-      #- name: Install setuptools for 2.7,3.4
-      #  run: pip install setuptools==39.2.0 --force-reinstall 
-
-      - name: Install Python 2 dependencies
-        if: ${{ contains(matrix.python-version, '2.7') }}
-        # certifi dropped support for Python 2 in 2020.4.5.2 but only started
-        # using Python 3 syntax in 2022.5.18. 2021.10.8 is the last release with
-        # Python 2 support.
-        run: pip install certifi==2021.10.8 requests==2.27.1 incremental==21.3.0
-
-      - name: Install Python 3.4 dependencies
-        if: ${{ contains(matrix.python-version, '3.4') }}
-        # certifi uses the 'typing' from Python 3.5 module starting in 2022.5.18
-        run: pip install six==1.16.0 certifi==2021.10.8 requests==2.21.0 "typing-extensions<4"  incremental==21.3.0 blinker==1.4 WebOb==1.8.7
-
       - name: Install Python 3.5 dependencies
         if: ${{ contains(matrix.python-version, '3.5') }}
         # typing-extensions dropped support for Python 3.5 in version 4
@@ -193,7 +106,7 @@ jobs:
       - name: Install Python 3.6 dependencies
         if: ${{ contains(matrix.python-version, '3.6') }}
         # typing-extensions dropped support for Python 3.6 in version 4.2
-        run: pip install six==1.16.0 "typing-extensions<4.2" requests==2.27.0
+        run: pip install six==1.16.0 "typing-extensions<4.2" requests==2.27.0 blinker==1.5
 
       - name: Set the framework
         run: echo ${{ matrix.framework }} >> $GITHUB_ENV