diff --git a/CHANGELOG.md b/CHANGELOG.md
index 625bdd93d13..7387ae519af 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -12,6 +12,7 @@
 * Add `IndentationWidth` configuration for `Layout/Tab` cop. ([@rrosenblum][])
 * [#4854](https://github.com/bbatsov/rubocop/pull/4854): Add new `Lint/RegexpAsCondition` cop. ([@pocke][])
 * [#4862](https://github.com/bbatsov/rubocop/pull/4862): Add `MethodDefineMacros` option to `Naming/PredicateName` cop. ([@koic][])
+* [#4840](https://github.com/bbatsov/rubocop/pull/4840): Add new `Style/MixinUsage` cop. ([@koic][])
 
 ### Bug fixes
 
diff --git a/config/enabled.yml b/config/enabled.yml
index 004eaf04c35..2ffef85fbcc 100644
--- a/config/enabled.yml
+++ b/config/enabled.yml
@@ -996,6 +996,10 @@ Style/TernaryParentheses:
   Description: 'Checks for use of parentheses around ternary conditions.'
   Enabled: true
 
+Style/MixinUsage:
+  Description: 'Checks that `include`, `extend` and `prepend` exists at the top level.'
+  Enabled: true
+
 Style/TrailingCommaInArguments:
   Description: 'Checks for trailing comma in argument lists.'
   StyleGuide: '#no-trailing-params-comma'
diff --git a/lib/rubocop.rb b/lib/rubocop.rb
index aec8d3cfe7e..e473f9628ff 100644
--- a/lib/rubocop.rb
+++ b/lib/rubocop.rb
@@ -400,6 +400,7 @@
 require_relative 'rubocop/cop/style/min_max'
 require_relative 'rubocop/cop/style/missing_else'
 require_relative 'rubocop/cop/style/mixin_grouping'
+require_relative 'rubocop/cop/style/mixin_usage'
 require_relative 'rubocop/cop/style/module_function'
 require_relative 'rubocop/cop/style/multiline_block_chain'
 require_relative 'rubocop/cop/style/multiline_if_then'
diff --git a/lib/rubocop/cop/style/mixin_usage.rb b/lib/rubocop/cop/style/mixin_usage.rb
new file mode 100644
index 00000000000..1ad42caa317
--- /dev/null
+++ b/lib/rubocop/cop/style/mixin_usage.rb
@@ -0,0 +1,73 @@
+# frozen_string_literal: true
+
+module RuboCop
+  module Cop
+    module Style
+      # This cop checks that `include`, `extend` and `prepend` exists at
+      # the top level.
+      # Using these at the top level affects the behavior of `Object`.
+      # There will not be using `include`, `extend` and `prepend` at
+      # the top level. Let's use it inside `class` or `module`.
+      #
+      # @example
+      #   # bad
+      #   include M
+      #
+      #   class C
+      #   end
+      #
+      #   # bad
+      #   extend M
+      #
+      #   class C
+      #   end
+      #
+      #   # bad
+      #   prepend M
+      #
+      #   class C
+      #   end
+      #
+      #   # good
+      #   class C
+      #     include M
+      #   end
+      #
+      #   # good
+      #   class C
+      #     extend M
+      #   end
+      #
+      #   # good
+      #   class C
+      #     prepend M
+      #   end
+      class MixinUsage < Cop
+        MSG = '`%<statement>s` is used at the top level. Use inside `class` ' \
+              'or `module`.'.freeze
+
+        def_node_matcher :include_statement, <<-PATTERN
+          (send nil? ${:include :extend :prepend}
+            (const nil? _))
+        PATTERN
+
+        def on_send(node)
+          return unless (statement = include_statement(node))
+          return unless top_level_node?(node)
+
+          add_offense(node, message: format(MSG, statement: statement))
+        end
+
+        private
+
+        def top_level_node?(node)
+          if node.parent.parent.nil?
+            node.sibling_index.zero?
+          else
+            top_level_node?(node.parent)
+          end
+        end
+      end
+    end
+  end
+end
diff --git a/manual/cops.md b/manual/cops.md
index a7d7b436ac0..c246cb7b055 100644
--- a/manual/cops.md
+++ b/manual/cops.md
@@ -408,6 +408,7 @@ In the following section you find all available cops:
 * [Style/MinMax](cops_style.md#styleminmax)
 * [Style/MissingElse](cops_style.md#stylemissingelse)
 * [Style/MixinGrouping](cops_style.md#stylemixingrouping)
+* [Style/MixinUsage](cops_style.md#stylemixinusage)
 * [Style/ModuleFunction](cops_style.md#stylemodulefunction)
 * [Style/MultilineBlockChain](cops_style.md#stylemultilineblockchain)
 * [Style/MultilineIfModifier](cops_style.md#stylemultilineifmodifier)
diff --git a/manual/cops_style.md b/manual/cops_style.md
index 51501df0be3..1366f93626b 100644
--- a/manual/cops_style.md
+++ b/manual/cops_style.md
@@ -2051,6 +2051,55 @@ SupportedStyles | separated, grouped
 
 * [https://github.com/bbatsov/ruby-style-guide#mixin-grouping](https://github.com/bbatsov/ruby-style-guide#mixin-grouping)
 
+## Style/MixinUsage
+
+Enabled by default | Supports autocorrection
+--- | ---
+Enabled | No
+
+This cop checks that `include`, `extend` and `prepend` exists at
+the top level.
+Using these at the top level affects the behavior of `Object`.
+There will not be using `include`, `extend` and `prepend` at
+the top level. Let's use it inside `class` or `module`.
+
+### Example
+
+```ruby
+# bad
+include M
+
+class C
+end
+
+# bad
+extend M
+
+class C
+end
+
+# bad
+prepend M
+
+class C
+end
+
+# good
+class C
+  include M
+end
+
+# good
+class C
+  extend M
+end
+
+# good
+class C
+  prepend M
+end
+```
+
 ## Style/ModuleFunction
 
 Enabled by default | Supports autocorrection
diff --git a/spec/rubocop/cop/style/mixin_usage_spec.rb b/spec/rubocop/cop/style/mixin_usage_spec.rb
new file mode 100644
index 00000000000..f557038d1c7
--- /dev/null
+++ b/spec/rubocop/cop/style/mixin_usage_spec.rb
@@ -0,0 +1,75 @@
+# frozen_string_literal: true
+
+describe RuboCop::Cop::Style::MixinUsage do
+  let(:config) { RuboCop::Config.new }
+  subject(:cop) { described_class.new(config) }
+
+  context 'include' do
+    it 'registers an offense when using outside class' do
+      expect_offense(<<-RUBY.strip_indent)
+        include M
+        ^^^^^^^^^ `include` is used at the top level. Use inside `class` or `module`.
+        class C
+        end
+      RUBY
+    end
+
+    it 'does not register an offense when using inside class' do
+      expect_no_offenses(<<-RUBY.strip_indent)
+        class C
+          include M
+        end
+      RUBY
+    end
+  end
+
+  context 'extend' do
+    it 'registers an offense when using outside class' do
+      expect_offense(<<-RUBY.strip_indent)
+        extend M
+        ^^^^^^^^ `extend` is used at the top level. Use inside `class` or `module`.
+        class C
+        end
+      RUBY
+    end
+
+    it 'does not register an offense when using inside class' do
+      expect_no_offenses(<<-RUBY.strip_indent)
+        class C
+          extend M
+        end
+      RUBY
+    end
+  end
+
+  context 'prepend' do
+    it 'registers an offense when using outside class' do
+      expect_offense(<<-RUBY.strip_indent)
+        prepend M
+        ^^^^^^^^^ `prepend` is used at the top level. Use inside `class` or `module`.
+        class C
+        end
+      RUBY
+    end
+
+    it 'does not register an offense when using inside class' do
+      expect_no_offenses(<<-RUBY.strip_indent)
+        class C
+          prepend M
+        end
+      RUBY
+    end
+  end
+
+  it 'does not register an offense when using inside nested module' do
+    expect_no_offenses(<<-RUBY.strip_indent)
+      module M1
+        include M2
+
+        class C
+          include M3
+        end
+      end
+    RUBY
+  end
+end