diff --git a/prism_compile.c b/prism_compile.c
index 951630c265109d..20cf764ed2ecfe 100644
--- a/prism_compile.c
+++ b/prism_compile.c
@@ -1492,6 +1492,7 @@ pm_compile_defined_expr0(rb_iseq_t *iseq, const pm_node_t *node, LINK_ANCHOR *co
       case PM_RANGE_NODE:
       case PM_REGULAR_EXPRESSION_NODE:
       case PM_SOURCE_ENCODING_NODE:
+      case PM_SOURCE_FILE_NODE:
       case PM_STRING_NODE:
       case PM_SYMBOL_NODE:
       case PM_X_STRING_NODE:
diff --git a/test/ruby/test_compile_prism.rb b/test/ruby/test_compile_prism.rb
index 3cad58a1840ff1..6c5ac84b1b7572 100644
--- a/test/ruby/test_compile_prism.rb
+++ b/test/ruby/test_compile_prism.rb
@@ -111,6 +111,7 @@ def test_DefinedNode
       assert_prism_eval("defined? a && b")
       assert_prism_eval("defined? a || b")
       assert_prism_eval("defined? __ENCODING__")
+      assert_prism_eval("defined? __FILE__")
 
       assert_prism_eval("defined? %[1,2,3]")
       assert_prism_eval("defined? %q[1,2,3]")