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Data analysis notebooks for Mosaic-seq on K562 cells
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README.md

README.md

Global Analysis of 500 enhancers in K562 cells with Mosaic-seq

Overview

This repository described our scripts and piplines for using Mosaic-seq to functionally evaluate enhancers in K562 cells. Through optimization of key parameters of Mosaic-seq, we demonstrate that both primary and secondary target genes can be identified in the assay. Our investigation of > 500 enhancers in K562 cells reveals an enhancer-centric, interwoven regulatory network that converges to reguate the same sub-modules.

Over-view

Requirement

File Organization

Original Fastq Files

GEO link:

Notebooks (In developemnt)

Contributors

  • First Author: Russell Xie shiqi.xie@utsouthwestern.edu
  • Corresponding Author: Gary Hon gary.hon@utsouthwestern.edu

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