diff --git a/compiler/rustc_ast/src/ast.rs b/compiler/rustc_ast/src/ast.rs
index d0d98eb3d62d1..7f5213431f7d3 100644
--- a/compiler/rustc_ast/src/ast.rs
+++ b/compiler/rustc_ast/src/ast.rs
@@ -3304,9 +3304,13 @@ mod size_asserts {
     static_assert_size!(Impl, 136);
     static_assert_size!(Item, 136);
     static_assert_size!(ItemKind, 64);
-    static_assert_size!(LitKind, 24);
+    // This can be removed after i128:128 is in the bootstrap compiler's target.
+    #[cfg(not(bootstrap))]
+    static_assert_size!(LitKind, 32);
     static_assert_size!(Local, 72);
-    static_assert_size!(MetaItemLit, 40);
+    // This can be removed after i128:128 is in the bootstrap compiler's target.
+    #[cfg(not(bootstrap))]
+    static_assert_size!(MetaItemLit, 48);
     static_assert_size!(Param, 40);
     static_assert_size!(Pat, 72);
     static_assert_size!(Path, 24);
diff --git a/compiler/rustc_codegen_llvm/src/context.rs b/compiler/rustc_codegen_llvm/src/context.rs
index 1d1b6e6148dd2..f3b2caf9b803a 100644
--- a/compiler/rustc_codegen_llvm/src/context.rs
+++ b/compiler/rustc_codegen_llvm/src/context.rs
@@ -145,6 +145,14 @@ pub unsafe fn create_module<'ll>(
                 .replace("-Fi64", "");
         }
     }
+    if llvm_version < (18, 0, 0) {
+        if sess.target.arch == "x86" || sess.target.arch == "x86_64" {
+            // LLVM 18 adjusts i128 to be 128-bit aligned on x86 variants.
+            // Earlier LLVMs leave this as default alignment, so remove it.
+            // See https://reviews.llvm.org/D86310
+            target_data_layout = target_data_layout.replace("-i128:128", "");
+        }
+    }
 
     // Ensure the data-layout values hardcoded remain the defaults.
     if sess.target.is_builtin {
diff --git a/compiler/rustc_middle/src/mir/mod.rs b/compiler/rustc_middle/src/mir/mod.rs
index 36f5ba161d5f1..624ae8c22f9dc 100644
--- a/compiler/rustc_middle/src/mir/mod.rs
+++ b/compiler/rustc_middle/src/mir/mod.rs
@@ -1672,13 +1672,19 @@ mod size_asserts {
     use super::*;
     use rustc_data_structures::static_assert_size;
     // tidy-alphabetical-start
-    static_assert_size!(BasicBlockData<'_>, 136);
+    // This can be removed after i128:128 is in the bootstrap compiler's target.
+    #[cfg(not(bootstrap))]
+    static_assert_size!(BasicBlockData<'_>, 144);
     static_assert_size!(LocalDecl<'_>, 40);
     static_assert_size!(SourceScopeData<'_>, 72);
     static_assert_size!(Statement<'_>, 32);
     static_assert_size!(StatementKind<'_>, 16);
-    static_assert_size!(Terminator<'_>, 104);
-    static_assert_size!(TerminatorKind<'_>, 88);
+    // This can be removed after i128:128 is in the bootstrap compiler's target.
+    #[cfg(not(bootstrap))]
+    static_assert_size!(Terminator<'_>, 112);
+    // This can be removed after i128:128 is in the bootstrap compiler's target.
+    #[cfg(not(bootstrap))]
+    static_assert_size!(TerminatorKind<'_>, 96);
     static_assert_size!(VarDebugInfo<'_>, 88);
     // tidy-alphabetical-end
 }
diff --git a/compiler/rustc_target/src/spec/targets/i386_apple_ios.rs b/compiler/rustc_target/src/spec/targets/i386_apple_ios.rs
index 13f8b6b5a0a05..a221538b9022f 100644
--- a/compiler/rustc_target/src/spec/targets/i386_apple_ios.rs
+++ b/compiler/rustc_target/src/spec/targets/i386_apple_ios.rs
@@ -11,7 +11,7 @@ pub fn target() -> Target {
         llvm_target: ios_sim_llvm_target(arch).into(),
         pointer_width: 32,
         data_layout: "e-m:o-p:32:32-p270:32:32-p271:32:32-p272:64:64-\
-            f64:32:64-f80:128-n8:16:32-S128"
+            i128:128-f64:32:64-f80:128-n8:16:32-S128"
             .into(),
         arch: arch.target_arch(),
         options: TargetOptions { max_atomic_width: Some(64), ..opts("ios", arch) },
diff --git a/compiler/rustc_target/src/spec/targets/i586_pc_nto_qnx700.rs b/compiler/rustc_target/src/spec/targets/i586_pc_nto_qnx700.rs
index 3ebf4bcf5231d..ea8b919e7480d 100644
--- a/compiler/rustc_target/src/spec/targets/i586_pc_nto_qnx700.rs
+++ b/compiler/rustc_target/src/spec/targets/i586_pc_nto_qnx700.rs
@@ -5,7 +5,7 @@ pub fn target() -> Target {
         llvm_target: "i586-pc-unknown".into(),
         pointer_width: 32,
         data_layout: "e-m:e-p:32:32-p270:32:32-p271:32:32-p272:64:64-\
-            f64:32:64-f80:32-n8:16:32-S128"
+            i128:128-f64:32:64-f80:32-n8:16:32-S128"
             .into(),
         arch: "x86".into(),
         options: TargetOptions {
diff --git a/compiler/rustc_target/src/spec/targets/i586_unknown_netbsd.rs b/compiler/rustc_target/src/spec/targets/i586_unknown_netbsd.rs
index 8375fa4c0c0fb..574dc658b78c5 100644
--- a/compiler/rustc_target/src/spec/targets/i586_unknown_netbsd.rs
+++ b/compiler/rustc_target/src/spec/targets/i586_unknown_netbsd.rs
@@ -10,7 +10,7 @@ pub fn target() -> Target {
         llvm_target: "i586-unknown-netbsdelf".into(),
         pointer_width: 32,
         data_layout: "e-m:e-p:32:32-p270:32:32-p271:32:32-p272:64:64-\
-            f64:32:64-f80:32-n8:16:32-S128"
+            i128:128-f64:32:64-f80:32-n8:16:32-S128"
             .into(),
         arch: "x86".into(),
         options: TargetOptions { mcount: "__mcount".into(), ..base },
diff --git a/compiler/rustc_target/src/spec/targets/i686_apple_darwin.rs b/compiler/rustc_target/src/spec/targets/i686_apple_darwin.rs
index 59069fe4e3a92..25617b4436cb6 100644
--- a/compiler/rustc_target/src/spec/targets/i686_apple_darwin.rs
+++ b/compiler/rustc_target/src/spec/targets/i686_apple_darwin.rs
@@ -18,7 +18,7 @@ pub fn target() -> Target {
         llvm_target: macos_llvm_target(Arch::I686).into(),
         pointer_width: 32,
         data_layout: "e-m:o-p:32:32-p270:32:32-p271:32:32-p272:64:64-\
-            f64:32:64-f80:128-n8:16:32-S128"
+            i128:128-f64:32:64-f80:128-n8:16:32-S128"
             .into(),
         arch: arch.target_arch(),
         options: TargetOptions { mcount: "\u{1}mcount".into(), ..base },
diff --git a/compiler/rustc_target/src/spec/targets/i686_linux_android.rs b/compiler/rustc_target/src/spec/targets/i686_linux_android.rs
index 79471040f0da2..12ebf0c72f839 100644
--- a/compiler/rustc_target/src/spec/targets/i686_linux_android.rs
+++ b/compiler/rustc_target/src/spec/targets/i686_linux_android.rs
@@ -17,7 +17,7 @@ pub fn target() -> Target {
         llvm_target: "i686-linux-android".into(),
         pointer_width: 32,
         data_layout: "e-m:e-p:32:32-p270:32:32-p271:32:32-p272:64:64-\
-            f64:32:64-f80:32-n8:16:32-S128"
+            i128:128-f64:32:64-f80:32-n8:16:32-S128"
             .into(),
         arch: "x86".into(),
         options: TargetOptions { supported_sanitizers: SanitizerSet::ADDRESS, ..base },
diff --git a/compiler/rustc_target/src/spec/targets/i686_pc_windows_gnu.rs b/compiler/rustc_target/src/spec/targets/i686_pc_windows_gnu.rs
index 8d4a39b581143..1181803441437 100644
--- a/compiler/rustc_target/src/spec/targets/i686_pc_windows_gnu.rs
+++ b/compiler/rustc_target/src/spec/targets/i686_pc_windows_gnu.rs
@@ -19,7 +19,7 @@ pub fn target() -> Target {
         llvm_target: "i686-pc-windows-gnu".into(),
         pointer_width: 32,
         data_layout: "e-m:x-p:32:32-p270:32:32-p271:32:32-p272:64:64-\
-            i64:64-f80:32-n8:16:32-a:0:32-S32"
+            i64:64-i128:128-f80:32-n8:16:32-a:0:32-S32"
             .into(),
         arch: "x86".into(),
         options: base,
diff --git a/compiler/rustc_target/src/spec/targets/i686_pc_windows_gnullvm.rs b/compiler/rustc_target/src/spec/targets/i686_pc_windows_gnullvm.rs
index bb410cd8caf2f..f4e33b8817887 100644
--- a/compiler/rustc_target/src/spec/targets/i686_pc_windows_gnullvm.rs
+++ b/compiler/rustc_target/src/spec/targets/i686_pc_windows_gnullvm.rs
@@ -18,7 +18,7 @@ pub fn target() -> Target {
         llvm_target: "i686-pc-windows-gnu".into(),
         pointer_width: 32,
         data_layout: "e-m:x-p:32:32-p270:32:32-p271:32:32-p272:64:64-\
-            i64:64-f80:32-n8:16:32-a:0:32-S32"
+            i64:64-i128:128-f80:32-n8:16:32-a:0:32-S32"
             .into(),
         arch: "x86".into(),
         options: base,
diff --git a/compiler/rustc_target/src/spec/targets/i686_pc_windows_msvc.rs b/compiler/rustc_target/src/spec/targets/i686_pc_windows_msvc.rs
index 5abc3017bf80c..9f1c8f4676cb3 100644
--- a/compiler/rustc_target/src/spec/targets/i686_pc_windows_msvc.rs
+++ b/compiler/rustc_target/src/spec/targets/i686_pc_windows_msvc.rs
@@ -25,7 +25,7 @@ pub fn target() -> Target {
         llvm_target: "i686-pc-windows-msvc".into(),
         pointer_width: 32,
         data_layout: "e-m:x-p:32:32-p270:32:32-p271:32:32-p272:64:64-\
-            i64:64-f80:128-n8:16:32-a:0:32-S32"
+            i64:64-i128:128-f80:128-n8:16:32-a:0:32-S32"
             .into(),
         arch: "x86".into(),
         options: base,
diff --git a/compiler/rustc_target/src/spec/targets/i686_unknown_freebsd.rs b/compiler/rustc_target/src/spec/targets/i686_unknown_freebsd.rs
index 927b2ab877ddf..d90f481c68cf4 100644
--- a/compiler/rustc_target/src/spec/targets/i686_unknown_freebsd.rs
+++ b/compiler/rustc_target/src/spec/targets/i686_unknown_freebsd.rs
@@ -11,7 +11,7 @@ pub fn target() -> Target {
         llvm_target: "i686-unknown-freebsd".into(),
         pointer_width: 32,
         data_layout: "e-m:e-p:32:32-p270:32:32-p271:32:32-p272:64:64-\
-            f64:32:64-f80:32-n8:16:32-S128"
+            i128:128-f64:32:64-f80:32-n8:16:32-S128"
             .into(),
         arch: "x86".into(),
         options: base,
diff --git a/compiler/rustc_target/src/spec/targets/i686_unknown_haiku.rs b/compiler/rustc_target/src/spec/targets/i686_unknown_haiku.rs
index bc7fd6fbc68cd..330a390c9817d 100644
--- a/compiler/rustc_target/src/spec/targets/i686_unknown_haiku.rs
+++ b/compiler/rustc_target/src/spec/targets/i686_unknown_haiku.rs
@@ -11,7 +11,7 @@ pub fn target() -> Target {
         llvm_target: "i686-unknown-haiku".into(),
         pointer_width: 32,
         data_layout: "e-m:e-p:32:32-p270:32:32-p271:32:32-p272:64:64-\
-            f64:32:64-f80:32-n8:16:32-S128"
+            i128:128-f64:32:64-f80:32-n8:16:32-S128"
             .into(),
         arch: "x86".into(),
         options: base,
diff --git a/compiler/rustc_target/src/spec/targets/i686_unknown_hurd_gnu.rs b/compiler/rustc_target/src/spec/targets/i686_unknown_hurd_gnu.rs
index 6884e078c27e5..c32f7177c1a09 100644
--- a/compiler/rustc_target/src/spec/targets/i686_unknown_hurd_gnu.rs
+++ b/compiler/rustc_target/src/spec/targets/i686_unknown_hurd_gnu.rs
@@ -11,7 +11,7 @@ pub fn target() -> Target {
         llvm_target: "i686-unknown-hurd-gnu".into(),
         pointer_width: 32,
         data_layout: "e-m:e-p:32:32-p270:32:32-p271:32:32-p272:64:64-\
-            f64:32:64-f80:32-n8:16:32-S128"
+            i128:128-f64:32:64-f80:32-n8:16:32-S128"
             .into(),
         arch: "x86".into(),
         options: base,
diff --git a/compiler/rustc_target/src/spec/targets/i686_unknown_linux_gnu.rs b/compiler/rustc_target/src/spec/targets/i686_unknown_linux_gnu.rs
index 3b7be48dbbc56..9bc38a72f4d39 100644
--- a/compiler/rustc_target/src/spec/targets/i686_unknown_linux_gnu.rs
+++ b/compiler/rustc_target/src/spec/targets/i686_unknown_linux_gnu.rs
@@ -12,7 +12,7 @@ pub fn target() -> Target {
         llvm_target: "i686-unknown-linux-gnu".into(),
         pointer_width: 32,
         data_layout: "e-m:e-p:32:32-p270:32:32-p271:32:32-p272:64:64-\
-            f64:32:64-f80:32-n8:16:32-S128"
+            i128:128-f64:32:64-f80:32-n8:16:32-S128"
             .into(),
         arch: "x86".into(),
         options: base,
diff --git a/compiler/rustc_target/src/spec/targets/i686_unknown_linux_musl.rs b/compiler/rustc_target/src/spec/targets/i686_unknown_linux_musl.rs
index ef58b4fb45881..4a82e0986c72b 100644
--- a/compiler/rustc_target/src/spec/targets/i686_unknown_linux_musl.rs
+++ b/compiler/rustc_target/src/spec/targets/i686_unknown_linux_musl.rs
@@ -25,7 +25,7 @@ pub fn target() -> Target {
         llvm_target: "i686-unknown-linux-musl".into(),
         pointer_width: 32,
         data_layout: "e-m:e-p:32:32-p270:32:32-p271:32:32-p272:64:64-\
-            f64:32:64-f80:32-n8:16:32-S128"
+            i128:128-f64:32:64-f80:32-n8:16:32-S128"
             .into(),
         arch: "x86".into(),
         options: base,
diff --git a/compiler/rustc_target/src/spec/targets/i686_unknown_netbsd.rs b/compiler/rustc_target/src/spec/targets/i686_unknown_netbsd.rs
index 5f3afbe5afdcd..ea72656607e4a 100644
--- a/compiler/rustc_target/src/spec/targets/i686_unknown_netbsd.rs
+++ b/compiler/rustc_target/src/spec/targets/i686_unknown_netbsd.rs
@@ -11,7 +11,7 @@ pub fn target() -> Target {
         llvm_target: "i686-unknown-netbsdelf".into(),
         pointer_width: 32,
         data_layout: "e-m:e-p:32:32-p270:32:32-p271:32:32-p272:64:64-\
-            f64:32:64-f80:32-n8:16:32-S128"
+            i128:128-f64:32:64-f80:32-n8:16:32-S128"
             .into(),
         arch: "x86".into(),
         options: TargetOptions { mcount: "__mcount".into(), ..base },
diff --git a/compiler/rustc_target/src/spec/targets/i686_unknown_openbsd.rs b/compiler/rustc_target/src/spec/targets/i686_unknown_openbsd.rs
index f44584a10be53..945dc0f896709 100644
--- a/compiler/rustc_target/src/spec/targets/i686_unknown_openbsd.rs
+++ b/compiler/rustc_target/src/spec/targets/i686_unknown_openbsd.rs
@@ -11,7 +11,7 @@ pub fn target() -> Target {
         llvm_target: "i686-unknown-openbsd".into(),
         pointer_width: 32,
         data_layout: "e-m:e-p:32:32-p270:32:32-p271:32:32-p272:64:64-\
-            f64:32:64-f80:32-n8:16:32-S128"
+            i128:128-f64:32:64-f80:32-n8:16:32-S128"
             .into(),
         arch: "x86".into(),
         options: base,
diff --git a/compiler/rustc_target/src/spec/targets/i686_unknown_uefi.rs b/compiler/rustc_target/src/spec/targets/i686_unknown_uefi.rs
index 25315e19cddb8..37d57c1cdf304 100644
--- a/compiler/rustc_target/src/spec/targets/i686_unknown_uefi.rs
+++ b/compiler/rustc_target/src/spec/targets/i686_unknown_uefi.rs
@@ -80,7 +80,7 @@ pub fn target() -> Target {
         llvm_target: "i686-unknown-windows-gnu".into(),
         pointer_width: 32,
         data_layout: "e-m:x-p:32:32-p270:32:32-p271:32:32-p272:64:64-\
-            i64:64-f80:32-n8:16:32-a:0:32-S32"
+            i64:64-i128:128-f80:32-n8:16:32-a:0:32-S32"
             .into(),
         arch: "x86".into(),
 
diff --git a/compiler/rustc_target/src/spec/targets/i686_uwp_windows_gnu.rs b/compiler/rustc_target/src/spec/targets/i686_uwp_windows_gnu.rs
index ec211a710eb07..0830033dc23d1 100644
--- a/compiler/rustc_target/src/spec/targets/i686_uwp_windows_gnu.rs
+++ b/compiler/rustc_target/src/spec/targets/i686_uwp_windows_gnu.rs
@@ -18,7 +18,7 @@ pub fn target() -> Target {
         llvm_target: "i686-pc-windows-gnu".into(),
         pointer_width: 32,
         data_layout: "e-m:x-p:32:32-p270:32:32-p271:32:32-p272:64:64-\
-            i64:64-f80:32-n8:16:32-a:0:32-S32"
+            i64:64-i128:128-f80:32-n8:16:32-a:0:32-S32"
             .into(),
         arch: "x86".into(),
         options: base,
diff --git a/compiler/rustc_target/src/spec/targets/i686_uwp_windows_msvc.rs b/compiler/rustc_target/src/spec/targets/i686_uwp_windows_msvc.rs
index 7cca2fc6b9f71..534dd6ee54fbb 100644
--- a/compiler/rustc_target/src/spec/targets/i686_uwp_windows_msvc.rs
+++ b/compiler/rustc_target/src/spec/targets/i686_uwp_windows_msvc.rs
@@ -9,7 +9,7 @@ pub fn target() -> Target {
         llvm_target: "i686-pc-windows-msvc".into(),
         pointer_width: 32,
         data_layout: "e-m:x-p:32:32-p270:32:32-p271:32:32-p272:64:64-\
-            i64:64-f80:128-n8:16:32-a:0:32-S32"
+            i64:64-i128:128-f80:128-n8:16:32-a:0:32-S32"
             .into(),
         arch: "x86".into(),
         options: base,
diff --git a/compiler/rustc_target/src/spec/targets/i686_win7_windows_msvc.rs b/compiler/rustc_target/src/spec/targets/i686_win7_windows_msvc.rs
index 5b91682e168ab..35ad81dc052bb 100644
--- a/compiler/rustc_target/src/spec/targets/i686_win7_windows_msvc.rs
+++ b/compiler/rustc_target/src/spec/targets/i686_win7_windows_msvc.rs
@@ -25,7 +25,7 @@ pub fn target() -> Target {
         llvm_target: "i686-pc-windows-msvc".into(),
         pointer_width: 32,
         data_layout: "e-m:x-p:32:32-p270:32:32-p271:32:32-p272:64:64-\
-            i64:64-f80:128-n8:16:32-a:0:32-S32"
+            i64:64-i128:128-f80:128-n8:16:32-a:0:32-S32"
             .into(),
         arch: "x86".into(),
         options: base,
diff --git a/compiler/rustc_target/src/spec/targets/i686_wrs_vxworks.rs b/compiler/rustc_target/src/spec/targets/i686_wrs_vxworks.rs
index ee501c5165e0e..30c2295e40210 100644
--- a/compiler/rustc_target/src/spec/targets/i686_wrs_vxworks.rs
+++ b/compiler/rustc_target/src/spec/targets/i686_wrs_vxworks.rs
@@ -11,7 +11,7 @@ pub fn target() -> Target {
         llvm_target: "i686-unknown-linux-gnu".into(),
         pointer_width: 32,
         data_layout: "e-m:e-p:32:32-p270:32:32-p271:32:32-p272:64:64-\
-            f64:32:64-f80:32-n8:16:32-S128"
+            i128:128-f64:32:64-f80:32-n8:16:32-S128"
             .into(),
         arch: "x86".into(),
         options: base,
diff --git a/compiler/rustc_target/src/spec/targets/x86_64_apple_darwin.rs b/compiler/rustc_target/src/spec/targets/x86_64_apple_darwin.rs
index 59df3937ea6ff..356c67218681e 100644
--- a/compiler/rustc_target/src/spec/targets/x86_64_apple_darwin.rs
+++ b/compiler/rustc_target/src/spec/targets/x86_64_apple_darwin.rs
@@ -17,8 +17,8 @@ pub fn target() -> Target {
         // correctly, we do too.
         llvm_target: macos_llvm_target(arch).into(),
         pointer_width: 64,
-        data_layout: "e-m:o-p270:32:32-p271:32:32-p272:64:64-i64:64-f80:128-n8:16:32:64-S128"
-            .into(),
+        data_layout:
+            "e-m:o-p270:32:32-p271:32:32-p272:64:64-i64:64-i128:128-f80:128-n8:16:32:64-S128".into(),
         arch: arch.target_arch(),
         options: TargetOptions { mcount: "\u{1}mcount".into(), ..base },
     }
diff --git a/compiler/rustc_target/src/spec/targets/x86_64_apple_ios.rs b/compiler/rustc_target/src/spec/targets/x86_64_apple_ios.rs
index d0e2ac44a2a26..55165ea4ec68c 100644
--- a/compiler/rustc_target/src/spec/targets/x86_64_apple_ios.rs
+++ b/compiler/rustc_target/src/spec/targets/x86_64_apple_ios.rs
@@ -9,8 +9,8 @@ pub fn target() -> Target {
     Target {
         llvm_target: ios_sim_llvm_target(arch).into(),
         pointer_width: 64,
-        data_layout: "e-m:o-p270:32:32-p271:32:32-p272:64:64-i64:64-f80:128-n8:16:32:64-S128"
-            .into(),
+        data_layout:
+            "e-m:o-p270:32:32-p271:32:32-p272:64:64-i64:64-i128:128-f80:128-n8:16:32:64-S128".into(),
         arch: arch.target_arch(),
         options: TargetOptions { max_atomic_width: Some(128), ..base },
     }
diff --git a/compiler/rustc_target/src/spec/targets/x86_64_apple_ios_macabi.rs b/compiler/rustc_target/src/spec/targets/x86_64_apple_ios_macabi.rs
index 8ef4b88b8b1cf..ff21e48933324 100644
--- a/compiler/rustc_target/src/spec/targets/x86_64_apple_ios_macabi.rs
+++ b/compiler/rustc_target/src/spec/targets/x86_64_apple_ios_macabi.rs
@@ -12,8 +12,8 @@ pub fn target() -> Target {
     Target {
         llvm_target: llvm_target.into(),
         pointer_width: 64,
-        data_layout: "e-m:o-p270:32:32-p271:32:32-p272:64:64-i64:64-f80:128-n8:16:32:64-S128"
-            .into(),
+        data_layout:
+            "e-m:o-p270:32:32-p271:32:32-p272:64:64-i64:64-i128:128-f80:128-n8:16:32:64-S128".into(),
         arch: arch.target_arch(),
         options: TargetOptions { max_atomic_width: Some(128), ..base },
     }
diff --git a/compiler/rustc_target/src/spec/targets/x86_64_apple_tvos.rs b/compiler/rustc_target/src/spec/targets/x86_64_apple_tvos.rs
index 17efd437f2fc8..20b0161255314 100644
--- a/compiler/rustc_target/src/spec/targets/x86_64_apple_tvos.rs
+++ b/compiler/rustc_target/src/spec/targets/x86_64_apple_tvos.rs
@@ -6,8 +6,8 @@ pub fn target() -> Target {
     Target {
         llvm_target: tvos_sim_llvm_target(arch).into(),
         pointer_width: 64,
-        data_layout: "e-m:o-p270:32:32-p271:32:32-p272:64:64-i64:64-f80:128-n8:16:32:64-S128"
-            .into(),
+        data_layout:
+            "e-m:o-p270:32:32-p271:32:32-p272:64:64-i64:64-i128:128-f80:128-n8:16:32:64-S128".into(),
         arch: arch.target_arch(),
         options: TargetOptions { max_atomic_width: Some(128), ..opts("tvos", arch) },
     }
diff --git a/compiler/rustc_target/src/spec/targets/x86_64_apple_watchos_sim.rs b/compiler/rustc_target/src/spec/targets/x86_64_apple_watchos_sim.rs
index b1f72ee2f2124..806a58e980be6 100644
--- a/compiler/rustc_target/src/spec/targets/x86_64_apple_watchos_sim.rs
+++ b/compiler/rustc_target/src/spec/targets/x86_64_apple_watchos_sim.rs
@@ -6,8 +6,8 @@ pub fn target() -> Target {
     Target {
         llvm_target: watchos_sim_llvm_target(arch).into(),
         pointer_width: 64,
-        data_layout: "e-m:o-p270:32:32-p271:32:32-p272:64:64-i64:64-f80:128-n8:16:32:64-S128"
-            .into(),
+        data_layout:
+            "e-m:o-p270:32:32-p271:32:32-p272:64:64-i64:64-i128:128-f80:128-n8:16:32:64-S128".into(),
         arch: arch.target_arch(),
         options: TargetOptions { max_atomic_width: Some(128), ..opts("watchos", arch) },
     }
diff --git a/compiler/rustc_target/src/spec/targets/x86_64_fortanix_unknown_sgx.rs b/compiler/rustc_target/src/spec/targets/x86_64_fortanix_unknown_sgx.rs
index f4117edc3ff5d..c38a1a08536b9 100644
--- a/compiler/rustc_target/src/spec/targets/x86_64_fortanix_unknown_sgx.rs
+++ b/compiler/rustc_target/src/spec/targets/x86_64_fortanix_unknown_sgx.rs
@@ -75,8 +75,8 @@ pub fn target() -> Target {
     Target {
         llvm_target: "x86_64-elf".into(),
         pointer_width: 64,
-        data_layout: "e-m:e-p270:32:32-p271:32:32-p272:64:64-i64:64-f80:128-n8:16:32:64-S128"
-            .into(),
+        data_layout:
+            "e-m:e-p270:32:32-p271:32:32-p272:64:64-i64:64-i128:128-f80:128-n8:16:32:64-S128".into(),
         arch: "x86_64".into(),
         options: opts,
     }
diff --git a/compiler/rustc_target/src/spec/targets/x86_64_linux_android.rs b/compiler/rustc_target/src/spec/targets/x86_64_linux_android.rs
index 0e6d41abc9b40..30b1ee73630e8 100644
--- a/compiler/rustc_target/src/spec/targets/x86_64_linux_android.rs
+++ b/compiler/rustc_target/src/spec/targets/x86_64_linux_android.rs
@@ -16,8 +16,8 @@ pub fn target() -> Target {
     Target {
         llvm_target: "x86_64-linux-android".into(),
         pointer_width: 64,
-        data_layout: "e-m:e-p270:32:32-p271:32:32-p272:64:64-i64:64-f80:128-n8:16:32:64-S128"
-            .into(),
+        data_layout:
+            "e-m:e-p270:32:32-p271:32:32-p272:64:64-i64:64-i128:128-f80:128-n8:16:32:64-S128".into(),
         arch: "x86_64".into(),
         options: TargetOptions { supported_sanitizers: SanitizerSet::ADDRESS, ..base },
     }
diff --git a/compiler/rustc_target/src/spec/targets/x86_64_pc_nto_qnx710.rs b/compiler/rustc_target/src/spec/targets/x86_64_pc_nto_qnx710.rs
index 93aec4c425a2c..0ef015973998a 100644
--- a/compiler/rustc_target/src/spec/targets/x86_64_pc_nto_qnx710.rs
+++ b/compiler/rustc_target/src/spec/targets/x86_64_pc_nto_qnx710.rs
@@ -4,8 +4,8 @@ pub fn target() -> Target {
     Target {
         llvm_target: "x86_64-pc-unknown".into(),
         pointer_width: 64,
-        data_layout: "e-m:e-p270:32:32-p271:32:32-p272:64:64-i64:64-f80:128-n8:16:32:64-S128"
-            .into(),
+        data_layout:
+            "e-m:e-p270:32:32-p271:32:32-p272:64:64-i64:64-i128:128-f80:128-n8:16:32:64-S128".into(),
         arch: "x86_64".into(),
         options: TargetOptions {
             cpu: "x86-64".into(),
diff --git a/compiler/rustc_target/src/spec/targets/x86_64_pc_solaris.rs b/compiler/rustc_target/src/spec/targets/x86_64_pc_solaris.rs
index f15ad8dda63bc..ade4dd6d43190 100644
--- a/compiler/rustc_target/src/spec/targets/x86_64_pc_solaris.rs
+++ b/compiler/rustc_target/src/spec/targets/x86_64_pc_solaris.rs
@@ -13,8 +13,8 @@ pub fn target() -> Target {
     Target {
         llvm_target: "x86_64-pc-solaris".into(),
         pointer_width: 64,
-        data_layout: "e-m:e-p270:32:32-p271:32:32-p272:64:64-i64:64-f80:128-n8:16:32:64-S128"
-            .into(),
+        data_layout:
+            "e-m:e-p270:32:32-p271:32:32-p272:64:64-i64:64-i128:128-f80:128-n8:16:32:64-S128".into(),
         arch: "x86_64".into(),
         options: base,
     }
diff --git a/compiler/rustc_target/src/spec/targets/x86_64_pc_windows_gnu.rs b/compiler/rustc_target/src/spec/targets/x86_64_pc_windows_gnu.rs
index 6d3e072705176..9e964d248bf8f 100644
--- a/compiler/rustc_target/src/spec/targets/x86_64_pc_windows_gnu.rs
+++ b/compiler/rustc_target/src/spec/targets/x86_64_pc_windows_gnu.rs
@@ -16,8 +16,8 @@ pub fn target() -> Target {
     Target {
         llvm_target: "x86_64-pc-windows-gnu".into(),
         pointer_width: 64,
-        data_layout: "e-m:w-p270:32:32-p271:32:32-p272:64:64-i64:64-f80:128-n8:16:32:64-S128"
-            .into(),
+        data_layout:
+            "e-m:w-p270:32:32-p271:32:32-p272:64:64-i64:64-i128:128-f80:128-n8:16:32:64-S128".into(),
         arch: "x86_64".into(),
         options: base,
     }
diff --git a/compiler/rustc_target/src/spec/targets/x86_64_pc_windows_gnullvm.rs b/compiler/rustc_target/src/spec/targets/x86_64_pc_windows_gnullvm.rs
index a56ebfa585e2e..1facf9450cd2a 100644
--- a/compiler/rustc_target/src/spec/targets/x86_64_pc_windows_gnullvm.rs
+++ b/compiler/rustc_target/src/spec/targets/x86_64_pc_windows_gnullvm.rs
@@ -11,8 +11,8 @@ pub fn target() -> Target {
     Target {
         llvm_target: "x86_64-pc-windows-gnu".into(),
         pointer_width: 64,
-        data_layout: "e-m:w-p270:32:32-p271:32:32-p272:64:64-i64:64-f80:128-n8:16:32:64-S128"
-            .into(),
+        data_layout:
+            "e-m:w-p270:32:32-p271:32:32-p272:64:64-i64:64-i128:128-f80:128-n8:16:32:64-S128".into(),
         arch: "x86_64".into(),
         options: base,
     }
diff --git a/compiler/rustc_target/src/spec/targets/x86_64_pc_windows_msvc.rs b/compiler/rustc_target/src/spec/targets/x86_64_pc_windows_msvc.rs
index 3a4da91c2443f..357261073a8f7 100644
--- a/compiler/rustc_target/src/spec/targets/x86_64_pc_windows_msvc.rs
+++ b/compiler/rustc_target/src/spec/targets/x86_64_pc_windows_msvc.rs
@@ -10,8 +10,8 @@ pub fn target() -> Target {
     Target {
         llvm_target: "x86_64-pc-windows-msvc".into(),
         pointer_width: 64,
-        data_layout: "e-m:w-p270:32:32-p271:32:32-p272:64:64-i64:64-f80:128-n8:16:32:64-S128"
-            .into(),
+        data_layout:
+            "e-m:w-p270:32:32-p271:32:32-p272:64:64-i64:64-i128:128-f80:128-n8:16:32:64-S128".into(),
         arch: "x86_64".into(),
         options: base,
     }
diff --git a/compiler/rustc_target/src/spec/targets/x86_64_unikraft_linux_musl.rs b/compiler/rustc_target/src/spec/targets/x86_64_unikraft_linux_musl.rs
index e6159fca3aeaf..6c9d114754873 100644
--- a/compiler/rustc_target/src/spec/targets/x86_64_unikraft_linux_musl.rs
+++ b/compiler/rustc_target/src/spec/targets/x86_64_unikraft_linux_musl.rs
@@ -5,8 +5,8 @@ pub fn target() -> Target {
         llvm_target: "x86_64-unknown-linux-musl".into(),
         pointer_width: 64,
         arch: "x86_64".into(),
-        data_layout: "e-m:e-p270:32:32-p271:32:32-p272:64:64-i64:64-f80:128-n8:16:32:64-S128"
-            .into(),
+        data_layout:
+            "e-m:e-p270:32:32-p271:32:32-p272:64:64-i64:64-i128:128-f80:128-n8:16:32:64-S128".into(),
         options: TargetOptions {
             cpu: "x86-64".into(),
             plt_by_default: false,
diff --git a/compiler/rustc_target/src/spec/targets/x86_64_unknown_dragonfly.rs b/compiler/rustc_target/src/spec/targets/x86_64_unknown_dragonfly.rs
index 80adb8fa2d951..ce682bb800560 100644
--- a/compiler/rustc_target/src/spec/targets/x86_64_unknown_dragonfly.rs
+++ b/compiler/rustc_target/src/spec/targets/x86_64_unknown_dragonfly.rs
@@ -11,8 +11,8 @@ pub fn target() -> Target {
     Target {
         llvm_target: "x86_64-unknown-dragonfly".into(),
         pointer_width: 64,
-        data_layout: "e-m:e-p270:32:32-p271:32:32-p272:64:64-i64:64-f80:128-n8:16:32:64-S128"
-            .into(),
+        data_layout:
+            "e-m:e-p270:32:32-p271:32:32-p272:64:64-i64:64-i128:128-f80:128-n8:16:32:64-S128".into(),
         arch: "x86_64".into(),
         options: base,
     }
diff --git a/compiler/rustc_target/src/spec/targets/x86_64_unknown_freebsd.rs b/compiler/rustc_target/src/spec/targets/x86_64_unknown_freebsd.rs
index fa32103536708..6d6940e7891cd 100644
--- a/compiler/rustc_target/src/spec/targets/x86_64_unknown_freebsd.rs
+++ b/compiler/rustc_target/src/spec/targets/x86_64_unknown_freebsd.rs
@@ -14,8 +14,8 @@ pub fn target() -> Target {
     Target {
         llvm_target: "x86_64-unknown-freebsd".into(),
         pointer_width: 64,
-        data_layout: "e-m:e-p270:32:32-p271:32:32-p272:64:64-i64:64-f80:128-n8:16:32:64-S128"
-            .into(),
+        data_layout:
+            "e-m:e-p270:32:32-p271:32:32-p272:64:64-i64:64-i128:128-f80:128-n8:16:32:64-S128".into(),
         arch: "x86_64".into(),
         options: base,
     }
diff --git a/compiler/rustc_target/src/spec/targets/x86_64_unknown_fuchsia.rs b/compiler/rustc_target/src/spec/targets/x86_64_unknown_fuchsia.rs
index 5b19ed1b5ff15..50139e5c1d833 100644
--- a/compiler/rustc_target/src/spec/targets/x86_64_unknown_fuchsia.rs
+++ b/compiler/rustc_target/src/spec/targets/x86_64_unknown_fuchsia.rs
@@ -12,8 +12,8 @@ pub fn target() -> Target {
     Target {
         llvm_target: "x86_64-unknown-fuchsia".into(),
         pointer_width: 64,
-        data_layout: "e-m:e-p270:32:32-p271:32:32-p272:64:64-i64:64-f80:128-n8:16:32:64-S128"
-            .into(),
+        data_layout:
+            "e-m:e-p270:32:32-p271:32:32-p272:64:64-i64:64-i128:128-f80:128-n8:16:32:64-S128".into(),
         arch: "x86_64".into(),
         options: base,
     }
diff --git a/compiler/rustc_target/src/spec/targets/x86_64_unknown_haiku.rs b/compiler/rustc_target/src/spec/targets/x86_64_unknown_haiku.rs
index 0f927be962bfb..c00c689f7ef79 100644
--- a/compiler/rustc_target/src/spec/targets/x86_64_unknown_haiku.rs
+++ b/compiler/rustc_target/src/spec/targets/x86_64_unknown_haiku.rs
@@ -13,8 +13,8 @@ pub fn target() -> Target {
     Target {
         llvm_target: "x86_64-unknown-haiku".into(),
         pointer_width: 64,
-        data_layout: "e-m:e-p270:32:32-p271:32:32-p272:64:64-i64:64-f80:128-n8:16:32:64-S128"
-            .into(),
+        data_layout:
+            "e-m:e-p270:32:32-p271:32:32-p272:64:64-i64:64-i128:128-f80:128-n8:16:32:64-S128".into(),
         arch: "x86_64".into(),
         options: base,
     }
diff --git a/compiler/rustc_target/src/spec/targets/x86_64_unknown_hermit.rs b/compiler/rustc_target/src/spec/targets/x86_64_unknown_hermit.rs
index df191f515bd68..fb46848ba8c0b 100644
--- a/compiler/rustc_target/src/spec/targets/x86_64_unknown_hermit.rs
+++ b/compiler/rustc_target/src/spec/targets/x86_64_unknown_hermit.rs
@@ -5,8 +5,8 @@ pub fn target() -> Target {
         llvm_target: "x86_64-unknown-hermit".into(),
         pointer_width: 64,
         arch: "x86_64".into(),
-        data_layout: "e-m:e-p270:32:32-p271:32:32-p272:64:64-i64:64-f80:128-n8:16:32:64-S128"
-            .into(),
+        data_layout:
+            "e-m:e-p270:32:32-p271:32:32-p272:64:64-i64:64-i128:128-f80:128-n8:16:32:64-S128".into(),
         options: TargetOptions {
             cpu: "x86-64".into(),
             features: "+rdrnd,+rdseed".into(),
diff --git a/compiler/rustc_target/src/spec/targets/x86_64_unknown_illumos.rs b/compiler/rustc_target/src/spec/targets/x86_64_unknown_illumos.rs
index eb2b13cb5c26b..3e3f4921322c4 100644
--- a/compiler/rustc_target/src/spec/targets/x86_64_unknown_illumos.rs
+++ b/compiler/rustc_target/src/spec/targets/x86_64_unknown_illumos.rs
@@ -13,8 +13,8 @@ pub fn target() -> Target {
         // so we still pass Solaris to it
         llvm_target: "x86_64-pc-solaris".into(),
         pointer_width: 64,
-        data_layout: "e-m:e-p270:32:32-p271:32:32-p272:64:64-i64:64-f80:128-n8:16:32:64-S128"
-            .into(),
+        data_layout:
+            "e-m:e-p270:32:32-p271:32:32-p272:64:64-i64:64-i128:128-f80:128-n8:16:32:64-S128".into(),
         arch: "x86_64".into(),
         options: base,
     }
diff --git a/compiler/rustc_target/src/spec/targets/x86_64_unknown_l4re_uclibc.rs b/compiler/rustc_target/src/spec/targets/x86_64_unknown_l4re_uclibc.rs
index 7b86fe738b1e3..646623668c6cb 100644
--- a/compiler/rustc_target/src/spec/targets/x86_64_unknown_l4re_uclibc.rs
+++ b/compiler/rustc_target/src/spec/targets/x86_64_unknown_l4re_uclibc.rs
@@ -10,8 +10,8 @@ pub fn target() -> Target {
     Target {
         llvm_target: "x86_64-unknown-l4re-uclibc".into(),
         pointer_width: 64,
-        data_layout: "e-m:e-p270:32:32-p271:32:32-p272:64:64-i64:64-f80:128-n8:16:32:64-S128"
-            .into(),
+        data_layout:
+            "e-m:e-p270:32:32-p271:32:32-p272:64:64-i64:64-i128:128-f80:128-n8:16:32:64-S128".into(),
         arch: "x86_64".into(),
         options: base,
     }
diff --git a/compiler/rustc_target/src/spec/targets/x86_64_unknown_linux_gnu.rs b/compiler/rustc_target/src/spec/targets/x86_64_unknown_linux_gnu.rs
index bf10f7e5d2de3..2296b58f45dc0 100644
--- a/compiler/rustc_target/src/spec/targets/x86_64_unknown_linux_gnu.rs
+++ b/compiler/rustc_target/src/spec/targets/x86_64_unknown_linux_gnu.rs
@@ -19,8 +19,8 @@ pub fn target() -> Target {
     Target {
         llvm_target: "x86_64-unknown-linux-gnu".into(),
         pointer_width: 64,
-        data_layout: "e-m:e-p270:32:32-p271:32:32-p272:64:64-i64:64-f80:128-n8:16:32:64-S128"
-            .into(),
+        data_layout:
+            "e-m:e-p270:32:32-p271:32:32-p272:64:64-i64:64-i128:128-f80:128-n8:16:32:64-S128".into(),
         arch: "x86_64".into(),
         options: base,
     }
diff --git a/compiler/rustc_target/src/spec/targets/x86_64_unknown_linux_gnux32.rs b/compiler/rustc_target/src/spec/targets/x86_64_unknown_linux_gnux32.rs
index 1856c6afd52be..d4b6519262e98 100644
--- a/compiler/rustc_target/src/spec/targets/x86_64_unknown_linux_gnux32.rs
+++ b/compiler/rustc_target/src/spec/targets/x86_64_unknown_linux_gnux32.rs
@@ -16,7 +16,7 @@ pub fn target() -> Target {
         llvm_target: "x86_64-unknown-linux-gnux32".into(),
         pointer_width: 32,
         data_layout: "e-m:e-p:32:32-p270:32:32-p271:32:32-p272:64:64-\
-            i64:64-f80:128-n8:16:32:64-S128"
+            i64:64-i128:128-f80:128-n8:16:32:64-S128"
             .into(),
         arch: "x86_64".into(),
         options: base,
diff --git a/compiler/rustc_target/src/spec/targets/x86_64_unknown_linux_musl.rs b/compiler/rustc_target/src/spec/targets/x86_64_unknown_linux_musl.rs
index 8dc5503e336a6..c71dc65670c28 100644
--- a/compiler/rustc_target/src/spec/targets/x86_64_unknown_linux_musl.rs
+++ b/compiler/rustc_target/src/spec/targets/x86_64_unknown_linux_musl.rs
@@ -18,8 +18,8 @@ pub fn target() -> Target {
     Target {
         llvm_target: "x86_64-unknown-linux-musl".into(),
         pointer_width: 64,
-        data_layout: "e-m:e-p270:32:32-p271:32:32-p272:64:64-i64:64-f80:128-n8:16:32:64-S128"
-            .into(),
+        data_layout:
+            "e-m:e-p270:32:32-p271:32:32-p272:64:64-i64:64-i128:128-f80:128-n8:16:32:64-S128".into(),
         arch: "x86_64".into(),
         options: base,
     }
diff --git a/compiler/rustc_target/src/spec/targets/x86_64_unknown_linux_ohos.rs b/compiler/rustc_target/src/spec/targets/x86_64_unknown_linux_ohos.rs
index 35862656aa2fd..c25105f6e35cf 100644
--- a/compiler/rustc_target/src/spec/targets/x86_64_unknown_linux_ohos.rs
+++ b/compiler/rustc_target/src/spec/targets/x86_64_unknown_linux_ohos.rs
@@ -18,8 +18,8 @@ pub fn target() -> Target {
         // LLVM 15 doesn't support OpenHarmony yet, use a linux target instead.
         llvm_target: "x86_64-unknown-linux-musl".into(),
         pointer_width: 64,
-        data_layout: "e-m:e-p270:32:32-p271:32:32-p272:64:64-i64:64-f80:128-n8:16:32:64-S128"
-            .into(),
+        data_layout:
+            "e-m:e-p270:32:32-p271:32:32-p272:64:64-i64:64-i128:128-f80:128-n8:16:32:64-S128".into(),
         arch: "x86_64".into(),
         options: base,
     }
diff --git a/compiler/rustc_target/src/spec/targets/x86_64_unknown_netbsd.rs b/compiler/rustc_target/src/spec/targets/x86_64_unknown_netbsd.rs
index e2cee0513babf..466498acb0b7b 100644
--- a/compiler/rustc_target/src/spec/targets/x86_64_unknown_netbsd.rs
+++ b/compiler/rustc_target/src/spec/targets/x86_64_unknown_netbsd.rs
@@ -19,8 +19,8 @@ pub fn target() -> Target {
     Target {
         llvm_target: "x86_64-unknown-netbsd".into(),
         pointer_width: 64,
-        data_layout: "e-m:e-p270:32:32-p271:32:32-p272:64:64-i64:64-f80:128-n8:16:32:64-S128"
-            .into(),
+        data_layout:
+            "e-m:e-p270:32:32-p271:32:32-p272:64:64-i64:64-i128:128-f80:128-n8:16:32:64-S128".into(),
         arch: "x86_64".into(),
         options: TargetOptions { mcount: "__mcount".into(), ..base },
     }
diff --git a/compiler/rustc_target/src/spec/targets/x86_64_unknown_none.rs b/compiler/rustc_target/src/spec/targets/x86_64_unknown_none.rs
index 8f7655d8ccd35..ceded7790a643 100644
--- a/compiler/rustc_target/src/spec/targets/x86_64_unknown_none.rs
+++ b/compiler/rustc_target/src/spec/targets/x86_64_unknown_none.rs
@@ -30,8 +30,8 @@ pub fn target() -> Target {
     Target {
         llvm_target: "x86_64-unknown-none-elf".into(),
         pointer_width: 64,
-        data_layout: "e-m:e-p270:32:32-p271:32:32-p272:64:64-i64:64-f80:128-n8:16:32:64-S128"
-            .into(),
+        data_layout:
+            "e-m:e-p270:32:32-p271:32:32-p272:64:64-i64:64-i128:128-f80:128-n8:16:32:64-S128".into(),
         arch: "x86_64".into(),
         options: opts,
     }
diff --git a/compiler/rustc_target/src/spec/targets/x86_64_unknown_openbsd.rs b/compiler/rustc_target/src/spec/targets/x86_64_unknown_openbsd.rs
index 1133b50f3d223..b542a569bbd23 100644
--- a/compiler/rustc_target/src/spec/targets/x86_64_unknown_openbsd.rs
+++ b/compiler/rustc_target/src/spec/targets/x86_64_unknown_openbsd.rs
@@ -12,8 +12,8 @@ pub fn target() -> Target {
     Target {
         llvm_target: "x86_64-unknown-openbsd".into(),
         pointer_width: 64,
-        data_layout: "e-m:e-p270:32:32-p271:32:32-p272:64:64-i64:64-f80:128-n8:16:32:64-S128"
-            .into(),
+        data_layout:
+            "e-m:e-p270:32:32-p271:32:32-p272:64:64-i64:64-i128:128-f80:128-n8:16:32:64-S128".into(),
         arch: "x86_64".into(),
         options: base,
     }
diff --git a/compiler/rustc_target/src/spec/targets/x86_64_unknown_redox.rs b/compiler/rustc_target/src/spec/targets/x86_64_unknown_redox.rs
index c1f573112920d..550b7a3d28231 100644
--- a/compiler/rustc_target/src/spec/targets/x86_64_unknown_redox.rs
+++ b/compiler/rustc_target/src/spec/targets/x86_64_unknown_redox.rs
@@ -11,8 +11,8 @@ pub fn target() -> Target {
     Target {
         llvm_target: "x86_64-unknown-redox".into(),
         pointer_width: 64,
-        data_layout: "e-m:e-p270:32:32-p271:32:32-p272:64:64-i64:64-f80:128-n8:16:32:64-S128"
-            .into(),
+        data_layout:
+            "e-m:e-p270:32:32-p271:32:32-p272:64:64-i64:64-i128:128-f80:128-n8:16:32:64-S128".into(),
         arch: "x86_64".into(),
         options: base,
     }
diff --git a/compiler/rustc_target/src/spec/targets/x86_64_unknown_uefi.rs b/compiler/rustc_target/src/spec/targets/x86_64_unknown_uefi.rs
index 5abfb8162f709..95847e57a0fb0 100644
--- a/compiler/rustc_target/src/spec/targets/x86_64_unknown_uefi.rs
+++ b/compiler/rustc_target/src/spec/targets/x86_64_unknown_uefi.rs
@@ -32,8 +32,8 @@ pub fn target() -> Target {
     Target {
         llvm_target: "x86_64-unknown-windows".into(),
         pointer_width: 64,
-        data_layout: "e-m:w-p270:32:32-p271:32:32-p272:64:64-i64:64-f80:128-n8:16:32:64-S128"
-            .into(),
+        data_layout:
+            "e-m:w-p270:32:32-p271:32:32-p272:64:64-i64:64-i128:128-f80:128-n8:16:32:64-S128".into(),
         arch: "x86_64".into(),
 
         options: base,
diff --git a/compiler/rustc_target/src/spec/targets/x86_64_uwp_windows_gnu.rs b/compiler/rustc_target/src/spec/targets/x86_64_uwp_windows_gnu.rs
index a46d3a0e27bce..c2981ddbad69b 100644
--- a/compiler/rustc_target/src/spec/targets/x86_64_uwp_windows_gnu.rs
+++ b/compiler/rustc_target/src/spec/targets/x86_64_uwp_windows_gnu.rs
@@ -15,8 +15,8 @@ pub fn target() -> Target {
     Target {
         llvm_target: "x86_64-pc-windows-gnu".into(),
         pointer_width: 64,
-        data_layout: "e-m:w-p270:32:32-p271:32:32-p272:64:64-i64:64-f80:128-n8:16:32:64-S128"
-            .into(),
+        data_layout:
+            "e-m:w-p270:32:32-p271:32:32-p272:64:64-i64:64-i128:128-f80:128-n8:16:32:64-S128".into(),
         arch: "x86_64".into(),
         options: base,
     }
diff --git a/compiler/rustc_target/src/spec/targets/x86_64_uwp_windows_msvc.rs b/compiler/rustc_target/src/spec/targets/x86_64_uwp_windows_msvc.rs
index a3bc27aa0650e..3f0702c7ad60e 100644
--- a/compiler/rustc_target/src/spec/targets/x86_64_uwp_windows_msvc.rs
+++ b/compiler/rustc_target/src/spec/targets/x86_64_uwp_windows_msvc.rs
@@ -9,8 +9,8 @@ pub fn target() -> Target {
     Target {
         llvm_target: "x86_64-pc-windows-msvc".into(),
         pointer_width: 64,
-        data_layout: "e-m:w-p270:32:32-p271:32:32-p272:64:64-i64:64-f80:128-n8:16:32:64-S128"
-            .into(),
+        data_layout:
+            "e-m:w-p270:32:32-p271:32:32-p272:64:64-i64:64-i128:128-f80:128-n8:16:32:64-S128".into(),
         arch: "x86_64".into(),
         options: base,
     }
diff --git a/compiler/rustc_target/src/spec/targets/x86_64_win7_windows_msvc.rs b/compiler/rustc_target/src/spec/targets/x86_64_win7_windows_msvc.rs
index 5a59839ebc68d..fd26b6e8caead 100644
--- a/compiler/rustc_target/src/spec/targets/x86_64_win7_windows_msvc.rs
+++ b/compiler/rustc_target/src/spec/targets/x86_64_win7_windows_msvc.rs
@@ -10,8 +10,8 @@ pub fn target() -> Target {
     Target {
         llvm_target: "x86_64-win7-windows-msvc".into(),
         pointer_width: 64,
-        data_layout: "e-m:w-p270:32:32-p271:32:32-p272:64:64-i64:64-f80:128-n8:16:32:64-S128"
-            .into(),
+        data_layout:
+            "e-m:w-p270:32:32-p271:32:32-p272:64:64-i64:64-i128:128-f80:128-n8:16:32:64-S128".into(),
         arch: "x86_64".into(),
         options: base,
     }
diff --git a/compiler/rustc_target/src/spec/targets/x86_64_wrs_vxworks.rs b/compiler/rustc_target/src/spec/targets/x86_64_wrs_vxworks.rs
index 765239bdd39c2..f7a78b48f95d6 100644
--- a/compiler/rustc_target/src/spec/targets/x86_64_wrs_vxworks.rs
+++ b/compiler/rustc_target/src/spec/targets/x86_64_wrs_vxworks.rs
@@ -12,8 +12,8 @@ pub fn target() -> Target {
     Target {
         llvm_target: "x86_64-unknown-linux-gnu".into(),
         pointer_width: 64,
-        data_layout: "e-m:e-p270:32:32-p271:32:32-p272:64:64-i64:64-f80:128-n8:16:32:64-S128"
-            .into(),
+        data_layout:
+            "e-m:e-p270:32:32-p271:32:32-p272:64:64-i64:64-i128:128-f80:128-n8:16:32:64-S128".into(),
         arch: "x86_64".into(),
         options: base,
     }
diff --git a/compiler/rustc_target/src/spec/targets/x86_64h_apple_darwin.rs b/compiler/rustc_target/src/spec/targets/x86_64h_apple_darwin.rs
index 0c731e369ebc2..e0e4cb93e31e1 100644
--- a/compiler/rustc_target/src/spec/targets/x86_64h_apple_darwin.rs
+++ b/compiler/rustc_target/src/spec/targets/x86_64h_apple_darwin.rs
@@ -35,8 +35,8 @@ pub fn target() -> Target {
         // correctly, we do too.
         llvm_target: macos_llvm_target(arch).into(),
         pointer_width: 64,
-        data_layout: "e-m:o-p270:32:32-p271:32:32-p272:64:64-i64:64-f80:128-n8:16:32:64-S128"
-            .into(),
+        data_layout:
+            "e-m:o-p270:32:32-p271:32:32-p272:64:64-i64:64-i128:128-f80:128-n8:16:32:64-S128".into(),
         arch: arch.target_arch(),
         options: TargetOptions { mcount: "\u{1}mcount".into(), ..base },
     }
diff --git a/tests/codegen/i128-x86-align.rs b/tests/codegen/i128-x86-align.rs
new file mode 100644
index 0000000000000..aaf5785dc9ff3
--- /dev/null
+++ b/tests/codegen/i128-x86-align.rs
@@ -0,0 +1,103 @@
+// only-x86_64
+// compile-flags: -O -C no-prepopulate-passes --crate-type=lib
+
+// On LLVM 17 and earlier LLVM's own data layout specifies that i128 has 8 byte alignment,
+// while rustc wants it to have 16 byte alignment. This test checks that we handle this
+// correctly.
+
+// CHECK: %ScalarPair = type { i32, [3 x i32], i128 }
+// CHECK: %Struct = type { i32, i32, [2 x i32], i128 }
+
+#![feature(core_intrinsics)]
+
+#[repr(C)]
+#[derive(Clone, Copy)]
+pub struct ScalarPair {
+    a: i32,
+    b: i128,
+}
+
+#[no_mangle]
+pub fn load(x: &ScalarPair) -> ScalarPair {
+    // CHECK-LABEL: @load(
+    // CHECK-SAME: align 16 dereferenceable(32) %x
+    // CHECK:      [[A:%.*]] = load i32, ptr %x, align 16
+    // CHECK-NEXT: [[GEP:%.*]] = getelementptr inbounds i8, ptr %x, i64 16
+    // CHECK-NEXT: [[B:%.*]] = load i128, ptr [[GEP]], align 16
+    // CHECK-NEXT: [[IV1:%.*]] = insertvalue { i32, i128 } poison, i32 [[A]], 0
+    // CHECK-NEXT: [[IV2:%.*]] = insertvalue { i32, i128 } [[IV1]], i128 [[B]], 1
+    // CHECK-NEXT: ret { i32, i128 } [[IV2]]
+    *x
+}
+
+#[no_mangle]
+pub fn store(x: &mut ScalarPair) {
+    // CHECK-LABEL: @store(
+    // CHECK-SAME: align 16 dereferenceable(32) %x
+    // CHECK:      store i32 1, ptr %x, align 16
+    // CHECK-NEXT: [[GEP:%.*]] = getelementptr inbounds i8, ptr %x, i64 16
+    // CHECK-NEXT: store i128 2, ptr [[GEP]], align 16
+    *x = ScalarPair { a: 1, b: 2 };
+}
+
+#[no_mangle]
+pub fn alloca() {
+    // CHECK-LABEL: @alloca(
+    // CHECK:      [[X:%.*]] = alloca %ScalarPair, align 16
+    // CHECK:      store i32 1, ptr %x, align 16
+    // CHECK-NEXT: [[GEP:%.*]] = getelementptr inbounds i8, ptr %x, i64 16
+    // CHECK-NEXT: store i128 2, ptr [[GEP]], align 16
+    let mut x = ScalarPair { a: 1, b: 2 };
+    store(&mut x);
+}
+
+#[no_mangle]
+pub fn load_volatile(x: &ScalarPair) -> ScalarPair {
+    // CHECK-LABEL: @load_volatile(
+    // CHECK-SAME: align 16 dereferenceable(32) %x
+    // CHECK:      [[TMP:%.*]] = alloca %ScalarPair, align 16
+    // CHECK:      [[LOAD:%.*]] = load volatile %ScalarPair, ptr %x, align 16
+    // CHECK-NEXT: store %ScalarPair [[LOAD]], ptr [[TMP]], align 16
+    // CHECK-NEXT: [[A:%.*]] = load i32, ptr [[TMP]], align 16
+    // CHECK-NEXT: [[GEP:%.*]] = getelementptr inbounds i8, ptr [[TMP]], i64 16
+    // CHECK-NEXT: [[B:%.*]] = load i128, ptr [[GEP]], align 16
+    unsafe { std::intrinsics::volatile_load(x) }
+}
+
+#[no_mangle]
+pub fn transmute(x: ScalarPair) -> (std::mem::MaybeUninit<i128>, i128) {
+    // CHECK-LABEL: define { i128, i128 } @transmute(i32 noundef %x.0, i128 noundef %x.1)
+    // CHECK:       [[TMP:%.*]] = alloca { i128, i128 }, align 16
+    // CHECK-NEXT:  store i32 %x.0, ptr [[TMP]], align 16
+    // CHECK-NEXT:  [[GEP:%.*]] = getelementptr inbounds i8, ptr [[TMP]], i64 16
+    // CHECK-NEXT:  store i128 %x.1, ptr [[GEP]], align 16
+    // CHECK-NEXT:  [[LOAD1:%.*]] = load i128, ptr %_0, align 16
+    // CHECK-NEXT:  [[GEP2:%.*]] = getelementptr inbounds i8, ptr [[TMP]], i64 16
+    // CHECK-NEXT:  [[LOAD2:%.*]] = load i128, ptr [[GEP2]], align 16
+    // CHECK-NEXT:  [[IV1:%.*]] = insertvalue { i128, i128 } poison, i128 [[LOAD1]], 0
+    // CHECK-NEXT:  [[IV2:%.*]] = insertvalue { i128, i128 } [[IV1]], i128 [[LOAD2]], 1
+    // CHECK-NEXT:  ret { i128, i128 } [[IV2]]
+    unsafe { std::mem::transmute(x) }
+}
+
+#[repr(C)]
+#[derive(Clone, Copy)]
+pub struct Struct {
+    a: i32,
+    b: i32,
+    c: i128,
+}
+
+#[no_mangle]
+pub fn store_struct(x: &mut Struct) {
+    // CHECK-LABEL: @store_struct(
+    // CHECK-SAME: align 16 dereferenceable(32) %x
+    // CHECK:      [[TMP:%.*]] = alloca %Struct, align 16
+    // CHECK:      store i32 1, ptr [[TMP]], align 16
+    // CHECK-NEXT: [[GEP1:%.*]] = getelementptr inbounds %Struct, ptr [[TMP]], i32 0, i32 1
+    // CHECK-NEXT: store i32 2, ptr [[GEP1]], align 4
+    // CHECK-NEXT: [[GEP2:%.*]] = getelementptr inbounds %Struct, ptr [[TMP]], i32 0, i32 3
+    // CHECK-NEXT: store i128 3, ptr [[GEP2]], align 16
+    // CHECK-NEXT: call void @llvm.memcpy.p0.p0.i64(ptr align 16 %x, ptr align 16 [[TMP]], i64 32, i1 false)
+    *x = Struct { a: 1, b: 2, c: 3 };
+}