diff --git a/src/tools/compiletest/src/header.rs b/src/tools/compiletest/src/header.rs
index dc5818201b6d2..e1a9aff155cdb 100644
--- a/src/tools/compiletest/src/header.rs
+++ b/src/tools/compiletest/src/header.rs
@@ -1010,9 +1010,6 @@ fn iter_header(
     if mode == Mode::CoverageRun {
         let extra_directives: &[&str] = &[
             "needs-profiler-support",
-            // FIXME(mati865): MinGW GCC miscompiles compiler-rt profiling library but with Clang it works
-            // properly. Since we only have GCC on the CI ignore the test for now.
-            "ignore-windows-gnu",
             // FIXME(pietroalbini): this test currently does not work on cross-compiled
             // targets because remote-test is not capable of sending back the *.profraw
             // files generated by the LLVM instrumentation.
diff --git a/tests/run-make/optimization-remarks-dir-pgo/Makefile b/tests/run-make/optimization-remarks-dir-pgo/Makefile
index 3bc3d7d142887..57ffd6e70f00b 100644
--- a/tests/run-make/optimization-remarks-dir-pgo/Makefile
+++ b/tests/run-make/optimization-remarks-dir-pgo/Makefile
@@ -1,10 +1,6 @@
 # needs-profiler-support
-# ignore-windows-gnu
 # ignore-cross-compile
 
-# FIXME(mati865): MinGW GCC miscompiles compiler-rt profiling library but with Clang it works
-# properly. Since we only have GCC on the CI ignore the test for now.
-
 include ../tools.mk
 
 PROFILE_DIR=$(TMPDIR)/profiles
diff --git a/tests/run-make/pgo-branch-weights/Makefile b/tests/run-make/pgo-branch-weights/Makefile
index 4c9f8b2493ab8..eef696345a8fb 100644
--- a/tests/run-make/pgo-branch-weights/Makefile
+++ b/tests/run-make/pgo-branch-weights/Makefile
@@ -1,10 +1,6 @@
 # needs-profiler-support
-# ignore-windows-gnu
 # ignore-cross-compile
 
-# FIXME(mati865): MinGW GCC miscompiles compiler-rt profiling library but with Clang it works
-# properly. Since we only have GCC on the CI ignore the test for now.
-
 include ../tools.mk
 
 # For some very small programs GNU ld seems to not properly handle
diff --git a/tests/run-make/pgo-gen-lto/Makefile b/tests/run-make/pgo-gen-lto/Makefile
index 8b647846af3b3..54164c995222a 100644
--- a/tests/run-make/pgo-gen-lto/Makefile
+++ b/tests/run-make/pgo-gen-lto/Makefile
@@ -1,10 +1,6 @@
 # needs-profiler-support
-# ignore-windows-gnu
 # ignore-cross-compile
 
-# FIXME(mati865): MinGW GCC miscompiles compiler-rt profiling library but with Clang it works
-# properly. Since we only have GCC on the CI ignore the test for now.
-
 include ../tools.mk
 
 COMPILE_FLAGS=-Copt-level=3 -Clto=fat -Cprofile-generate="$(TMPDIR)"
diff --git a/tests/run-make/pgo-gen/Makefile b/tests/run-make/pgo-gen/Makefile
index bf32cfdb802f5..c1d456986fb28 100644
--- a/tests/run-make/pgo-gen/Makefile
+++ b/tests/run-make/pgo-gen/Makefile
@@ -1,10 +1,6 @@
 # needs-profiler-support
-# ignore-windows-gnu
 # ignore-cross-compile
 
-# FIXME(mati865): MinGW GCC miscompiles compiler-rt profiling library but with Clang it works
-# properly. Since we only have GCC on the CI ignore the test for now.
-
 include ../tools.mk
 
 COMPILE_FLAGS=-g -Cprofile-generate="$(TMPDIR)"
diff --git a/tests/run-make/pgo-indirect-call-promotion/Makefile b/tests/run-make/pgo-indirect-call-promotion/Makefile
index 542eb244d3959..8d1e69c4aba37 100644
--- a/tests/run-make/pgo-indirect-call-promotion/Makefile
+++ b/tests/run-make/pgo-indirect-call-promotion/Makefile
@@ -1,10 +1,6 @@
 # needs-profiler-support
-# ignore-windows-gnu
 # ignore-cross-compile
 
-# FIXME(mati865): MinGW GCC miscompiles compiler-rt profiling library but with Clang it works
-# properly. Since we only have GCC on the CI ignore the test for now.
-
 include ../tools.mk
 
 all:
diff --git a/tests/run-make/pgo-use/Makefile b/tests/run-make/pgo-use/Makefile
index 9f440118daee3..92098a4019c47 100644
--- a/tests/run-make/pgo-use/Makefile
+++ b/tests/run-make/pgo-use/Makefile
@@ -1,10 +1,6 @@
 # needs-profiler-support
-# ignore-windows-gnu
 # ignore-cross-compile
 
-# FIXME(mati865): MinGW GCC miscompiles compiler-rt profiling library but with Clang it works
-# properly. Since we only have GCC on the CI ignore the test for now.
-
 include ../tools.mk
 
 # This test makes sure that PGO profiling data leads to cold functions being
diff --git a/tests/run-make/track-pgo-dep-info/Makefile b/tests/run-make/track-pgo-dep-info/Makefile
index 6c7f67d0f0a9d..3afe3662fa753 100644
--- a/tests/run-make/track-pgo-dep-info/Makefile
+++ b/tests/run-make/track-pgo-dep-info/Makefile
@@ -1,5 +1,4 @@
 # needs-profiler-support
-# ignore-windows-gnu
 
 include ../tools.mk