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@sai-ma-group

sai-ma-group

README.md

Sai Ma Lab

Single-cell & spatial epigenomics · Multi-omics · Gene regulation · Aging & disease

Icahn School of Medicine at Mount Sinai

Lab Website • Publications •

About us

We develop experimental and computational technologies to understand how epigenetic regulation shapes cellular identity and state transitions in development, aging, and disease.

Research
🧬 Single-cell multi-omics DNA methylation, chromatin accessibility, Chromatin organization and transcriptomics
🧠 Aging & neurodegeneration Epigenetic regulation of aging and Alzheimer's disease
🩸 Hematopoiesis & leukemia Regulatory mechanisms underlying normal and malignant hematopoiesis
🧩 Technology development New single-cell and spatial epigenomic methods
💻 Computational genomics Methods for multimodal and regulatory genomics

Software & resources

Our GitHub repositories provide software, analysis pipelines, and resources developed by the Ma Lab.

⬇️ Explore our featured repositories below

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  1. SHARE-seq-alignmentV2 SHARE-seq-alignmentV2 Public

    Pipeline for demultiplexing and aligning both ATAC and RNA data generated in SHARE-seqV2

    Python 18 10

  2. fastDORC fastDORC Public

    R 2 1

  3. ME-seq-alignment-pipeline ME-seq-alignment-pipeline Public

    Forked from spiderzbh/ME-seq-alignment-pipeline

    Bash pipeline for ME-seq data processing from BCL or FASTQ. Performs demultiplexing, barcode parsing, trimming, and alignment. Generates fragment TSV files, CpG C and mC counts, non-CpG C and mC co…

    Python

Repositories

Showing 5 of 5 repositories

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