diff --git a/compiler/src/dotty/tools/dotc/transform/CheckUnused.scala b/compiler/src/dotty/tools/dotc/transform/CheckUnused.scala
index 4a5f4b0680cd..4b566f8603e3 100644
--- a/compiler/src/dotty/tools/dotc/transform/CheckUnused.scala
+++ b/compiler/src/dotty/tools/dotc/transform/CheckUnused.scala
@@ -697,7 +697,7 @@ object CheckUnused:
 
     def checkLocal(sym: Symbol, pos: SrcPos) =
       if ctx.settings.WunusedHas.locals
-        && !sym.is(InlineProxy)
+        && !sym.isOneOf(InlineProxy | Synthetic)
       then
         if sym.is(Mutable) && infos.asss(sym) then
           warnAt(pos)(UnusedSymbol.localVars)
diff --git a/tests/warn/i24263.scala b/tests/warn/i24263.scala
new file mode 100644
index 000000000000..fc4768de2597
--- /dev/null
+++ b/tests/warn/i24263.scala
@@ -0,0 +1,6 @@
+//> using options -Werror -Wunused:all
+
+object test {
+  def f(t: Tuple): Nothing = ???
+  val _ = (inputTuple: NamedTuple.NamedTuple[Tuple, Tuple]) => f(inputTuple)
+}