diff --git a/docs/changelog.rst b/docs/changelog.rst
index a7f7ef4da1..4fca65b2a4 100644
--- a/docs/changelog.rst
+++ b/docs/changelog.rst
@@ -6,6 +6,11 @@ Changelog
 `Unreleased`_
 -------------
 
+Fixed
+~~~~~
+
+- Crash on invalid regular expressions in ``method``, ``endpoint`` and ``tag`` CLI options. `#403`_
+
 `0.24.1`_ - 2020-02-08
 ----------------------
 
@@ -687,6 +692,7 @@ Fixed
 .. _0.3.0: https://github.com/kiwicom/schemathesis/compare/v0.2.0...v0.3.0
 .. _0.2.0: https://github.com/kiwicom/schemathesis/compare/v0.1.0...v0.2.0
 
+.. _#403: https://github.com/kiwicom/schemathesis/issues/403
 .. _#400: https://github.com/kiwicom/schemathesis/issues/400
 .. _#394: https://github.com/kiwicom/schemathesis/issues/394
 .. _#391: https://github.com/kiwicom/schemathesis/issues/391
diff --git a/src/schemathesis/cli/__init__.py b/src/schemathesis/cli/__init__.py
index 34bf80b6e8..0bb351d233 100644
--- a/src/schemathesis/cli/__init__.py
+++ b/src/schemathesis/cli/__init__.py
@@ -77,9 +77,26 @@ def schemathesis(pre_run: Optional[str] = None) -> None:
     type=str,
     multiple=True,
     help=r"Filter schemathesis test by endpoint pattern. Example: users/\d+",
+    callback=callbacks.validate_regex,
+)
+@click.option(
+    "--method",
+    "-M",
+    "methods",
+    type=str,
+    multiple=True,
+    help="Filter schemathesis test by HTTP method.",
+    callback=callbacks.validate_regex,
+)
+@click.option(
+    "--tag",
+    "-T",
+    "tags",
+    type=str,
+    multiple=True,
+    help="Filter schemathesis test by schema tag pattern.",
+    callback=callbacks.validate_regex,
 )
-@click.option("--method", "-M", "methods", type=str, multiple=True, help="Filter schemathesis test by HTTP method.")
-@click.option("--tag", "-T", "tags", type=str, multiple=True, help="Filter schemathesis test by schema tag pattern.")
 @click.option(
     "--workers",
     "-w",
diff --git a/src/schemathesis/cli/callbacks.py b/src/schemathesis/cli/callbacks.py
index 3353c90d0b..a5f7facd69 100644
--- a/src/schemathesis/cli/callbacks.py
+++ b/src/schemathesis/cli/callbacks.py
@@ -71,6 +71,17 @@ def validate_headers(
     return headers
 
 
+def validate_regex(ctx: click.core.Context, param: click.core.Parameter, raw_value: Tuple[str, ...]) -> Tuple[str, ...]:
+    if not raw_value:
+        return raw_value
+    for value in raw_value:
+        try:
+            re.compile(value)
+        except re.error as exc:
+            raise click.BadParameter(f"Invalid regex: {exc.args[0]}")
+    return raw_value
+
+
 def convert_verbosity(
     ctx: click.core.Context, param: click.core.Parameter, value: Optional[str]
 ) -> Optional[hypothesis.Verbosity]:
diff --git a/test/cli/test_callbacks.py b/test/cli/test_callbacks.py
index cd8c6d344c..09a5799af5 100644
--- a/test/cli/test_callbacks.py
+++ b/test/cli/test_callbacks.py
@@ -46,3 +46,9 @@ def test_reraise_format_error():
     with pytest.raises(click.BadParameter, match="Should be in KEY:VALUE format. Got: bla"):
         with callbacks.reraise_format_error("bla"):
             raise ValueError
+
+
+@pytest.mark.parametrize("value", ("+", "\\", "[",))
+def test_validate_regex(value):
+    with pytest.raises(click.BadParameter, match="Invalid regex: "):
+        callbacks.validate_regex(None, None, (value,))