From ebc85405e309e6a68a2f24b02dc6813ed578d141 Mon Sep 17 00:00:00 2001 From: Sean Davis Date: Sat, 16 Dec 2017 13:36:04 -0500 Subject: [PATCH] Update README.md --- README.md | 4 ++++ 1 file changed, 4 insertions(+) diff --git a/README.md b/README.md index 4726612..cf0495f 100644 --- a/README.md +++ b/README.md @@ -108,6 +108,10 @@ List of software packages (and the people developing these methods) for single-c - [monovar](https://bitbucket.org/hamimzafar/monovar) - [python] - Monovar is a single nucleotide variant (SNV) detection and genotyping algorithm for single-cell DNA sequencing data. It takes a list of bam files as input and outputs a vcf file containing the detected SNVs. - [SSrGE](https://github.com/lanagarmire/SSrGE) - [python] - SSrGE is an approach to identify SNVs correlated with Gene Expression using multiple regularized linear regressions. It contains its own pipeline to infer SNVs from scRNA-seq reads and is able to identify and sort genes and SNVs for a given cell subgroup. Deposited in [BioRvix in December 2016](http://biorxiv.org/content/early/2017/03/01/095810). +### Methylation + +- [DeepCpg](https://github.com/cangermueller/deepcpg) - [python] - DeepCpG is a deep neural network for predicting the methylation state of CpG dinucleotides in multiple cells. It allows to accurately impute incomplete DNA methylation profiles, to discover predictive sequence motifs, and to quantify the effect of sequence mutations. + ### Other applications - [BASIC](http://ttic.uchicago.edu/~aakhan/BASIC/) - [python] - BASIC is a semi-de novo assembly method to determine the full-length sequence of the BCR in single B cells from scRNA-seq data.