Mutserve

Mutserve is a variant caller for the mitochondrial genome to detect homoplasmic and heteroplasmic sites in sequence data. It is used by haplocheck and mtDNA-Server.

Quick Start

Mutserve requires sorted and indexed CRAM/BAM files as an input.

curl -sL mutserve.vercel.app | bash
./mutserve

Documentation

Full documentation for mutserve can be found here.

Limitations

The focus of mutserve is currenly on SNP calling and not on indels.

Contact

See here.

Citation

Weissensteiner H, Forer L, Fendt L, Kheirkhah A, Salas A, Kronenberg F, Schoenherr S. 2021. Contamination detection in sequencing studies using the mitochondrial phylogeny. Genome Res. 31: 309-316

Weissensteiner H, Forer L, Fuchsberger C, Schöpf B, Kloss-Brandstätter A, Specht G, Kronenberg F, Schönherr S. 2016. mtDNA-Server: next-generation sequencing data analysis of human mitochondrial DNA in the cloud. Nucleic Acids Res 44: W64–9.