I feel like want to leave my friends and go home.
Did they do something to annoy you?
Yes, I'm tired of listening to them.
Sometimes you just have to put up with some annoyances from your friends. Stay with your friends, it's rude to just ditch them.
I hate them and have no interest in talking to them.
You can always tell them you are going home. Make something up like having to do something important.