I'm starting to hate one of my best friends
Why do you think you are starting to hate your best friend?
It's just that we've been together for a really long time and he started getting extremely nosy and extremely conservative.
If your friend is changing and becoming someone you don't like, it is acceptable to drift apart from him. If you are concerned about him, you can have a frank talk with him about why he has changed, but you should be prepared to let the friendship go if he is defensive and won't listen to you.
I just want to make fun of him and make him lose his job.
I understand getting annoyed  by a friend but wanting them to lose their job seems excessive. They still were your friend at one point in time and if they're changing  then you should just end the friendship instead of wishing bad things on them.