I think I should cut off my best friend and ghost him
Where this come from suddenly? You don't want to be friends with him anymore?
No, I rather want him to move on and make a better life.
I see that you no longer feel close to your friend, but you shouldn't just cut him off and ghost him. Talk to your friend instead and tell him that you feel that you've grown apart.
I'm pretending I don't know him. He's a pussy who cant take a joke so I'm going to give him what he deserves
So I guess you are feeling this way because he took offense to your joke? If so, maybe the joke was too sensitive for him and he was hurt by it, so wouldn't you want to make amends? I am sure he cares about you and just wants time alone to cool off a bit because don't forgot you hurt him and not the other way around.