Do you think it would be weird to shave a line for my socks around my ankles?
Why would you do that?
I just think it would be more comfortable.
You're free to shave your body here however you want, especially if it makes things more convenient for you. If you shave the hair around your ankles to accommodate your socks, people might think that you're a bit eccentric. It's up to you whether the risk of seeming weird is worth the convenience.
I think I'll do it.
If that's what you want to do, then you should. Your grooming habits are no one's business but your own, so you should do what you think is best.