If it were up to me I would never talk to my sister again.
What did she do that would make you never want to talk to her?
She's just so stuck up and pisses me off all the time.
If she's actually doing things to piss you off then of course it's fine to be mad. You should try to talk to her about it and if she doesn't take it seriously then not talking to her or avoiding interactions with her should be fine.
I did that and now she's starting to piss me off even more.
It is normal for siblings to fight a bit. If it is getting out of control you should let your parents know what is going on.