I'm never loaning my mom money ever again.
Why would you not loan her money anymore?
She needs to live her life without my help.
If that's the only reason then you should think about how much your parents helped you out before before you jump to that decision.
They should have saved money then. Then they wouldn;t have to ask me for it.
Unless your parents are abusing the money you lend them or constantly asking then there's no reason you shouldn't be able to keep helping them. You didn't say they weren't paying you back so I would think it wouldn't be an issue. As their child you should think about how much they helped you growing up and be willing to help them out if you have the ability to.