Nothing he took helped make him feel better
What caused him to not feel well?
There were new people in the class, he couldn't get accustomed with it.
I think if he was feeling bad and nothing was helping then he should have seen a professional about it. Sometimes it's better to get advice from an expert, rather than trying to figure it out on your own.
He saw a professional, changed schools, and got help from family, but it did not help.
It is great that he saw a professional. In addition to seeing a professional, the individual also needs to make their best effort to make changes that will help their situation. I wish him all the best!