Two bugs just ruined my life.
How did bugs ruin your life?
I mean these two friends bug me.
It is fine to be annoyed with friend's sometimes. Saying that it is ruining your life may be a little unrealistic though! Hopefully there are not other things that are stressing you out to feel this way.
No, I'm going to say my life is completely ruined.
It may just be difficult to have other people truly take you seriously if you claim that every little thing is ruining your life. Then, if something really awful actually happens to you people will just assume you are being dramatic.