I can't handle my autosabotage anymore.
What's going on, are you finally done with self-sabotaging yourself?
I'm tired of fucking up my own life. I'm tired of being a loser.
Calling yourself names and getting in your own way is a bad way to do things. Give yourself a break and try not to be hard on yourself.
Stop laughing at me.
I am definitely not laughing at you as I am genuinely concerned about your well-being. I do hope you get help if you constantly try to self-sabotage. I know it's not healthy and I think you also know that it's not healthy, so I urge you to do something  about it.