Can I shut a friend down and ignore her?
Why do you want to ignore her?
She is too messy and chaotic, I can't handle her.
If she is toxic then I understand why you would feel this way. Try talking to her about this and if she continues then ignore her.
She isn't toxic, she just needs to clean up
Instead of ghosting her, tell her about her messiness and ask her to start trying to clean up after herself. Make a compromise with her and see if she is willing to change to make your friendship better.