I want to call my overly affectionate brother weird
What does he do that makes you feel weird about him?
I know he is trying to be close to me but I find him irritating.
You should be happy and proud that your brother is making an effort to be close to you. It is overly critical of you to call him names just because he wants to show affection.
I don't care about you.
Which is fine, I am just trying to help you and your brother have a good relationship. You should be grateful that you and your brother get a long so well.