diff --git a/spring-context-support/src/main/java/org/springframework/cache/caffeine/CaffeineCacheManager.java b/spring-context-support/src/main/java/org/springframework/cache/caffeine/CaffeineCacheManager.java
index 9087df30efa3..75a89b196d6d 100644
--- a/spring-context-support/src/main/java/org/springframework/cache/caffeine/CaffeineCacheManager.java
+++ b/spring-context-support/src/main/java/org/springframework/cache/caffeine/CaffeineCacheManager.java
@@ -106,9 +106,16 @@ public CaffeineCacheManager(String... cacheNames) {
 	 * with no creation of further cache regions at runtime.
 	 * <p>Calling this with a {@code null} collection argument resets the
 	 * mode to 'dynamic', allowing for further creation of caches again.
+	 * <p><b>Note:</b> Switching to static mode will remove all dynamically created
+	 * caches, while preserving custom caches registered via
+	 * {@link #registerCustomCache(String, com.github.benmanes.caffeine.cache.Cache)}.
 	 */
 	public void setCacheNames(@Nullable Collection<String> cacheNames) {
 		if (cacheNames != null) {
+			// Remove all non-custom caches before setting up static caches
+			this.cacheMap.keySet().retainAll(this.customCacheNames);
+
+			// Add the specified static caches
 			for (String name : cacheNames) {
 				this.cacheMap.put(name, createCaffeineCache(name));
 			}
diff --git a/spring-context-support/src/test/java/org/springframework/cache/caffeine/CaffeineCacheManagerTests.java b/spring-context-support/src/test/java/org/springframework/cache/caffeine/CaffeineCacheManagerTests.java
index 1f4bb58c5239..6c6bf569d7ae 100644
--- a/spring-context-support/src/test/java/org/springframework/cache/caffeine/CaffeineCacheManagerTests.java
+++ b/spring-context-support/src/test/java/org/springframework/cache/caffeine/CaffeineCacheManagerTests.java
@@ -16,6 +16,8 @@
 
 package org.springframework.cache.caffeine;
 
+import java.util.Arrays;
+import java.util.List;
 import java.util.concurrent.CompletableFuture;
 
 import com.github.benmanes.caffeine.cache.CacheLoader;
@@ -284,6 +286,68 @@ void setCacheNameNullRestoreDynamicMode() {
 		assertThat(cm.getCache("someCache")).isNotNull();
 	}
 
+	@Test
+	void setCacheNameShouldRemovePreviousDynamicCaches() {
+		CaffeineCacheManager manager = new CaffeineCacheManager();
+
+		// Given: Dynamic mode with some caches
+		manager.getCache("dynamicCache1");
+		manager.getCache("dynamicCache2");
+		assertThat(manager.getCacheNames())
+				.containsExactlyInAnyOrder("dynamicCache1", "dynamicCache2");
+
+		// When: Switch to static mode
+		manager.setCacheNames(Arrays.asList("staticCache1", "staticCache2"));
+
+		// Then: Only static caches should exist
+		assertThat(manager.getCacheNames())
+				.containsExactlyInAnyOrder("staticCache1", "staticCache2")
+				.as("Dynamic caches should be removed when switching to static mode");
+
+		// And: Dynamic caches should not be accessible
+		assertThat(manager.getCache("dynamicCache1")).isNull();
+		assertThat(manager.getCache("dynamicCache2")).isNull();
+	}
+
+	@Test
+	void setCacheNamesShouldPreserveCustomCaches() {
+		CaffeineCacheManager manager = new CaffeineCacheManager();
+
+		// Given: Custom cache registered
+		com.github.benmanes.caffeine.cache.Cache<Object, Object> customNativeCache = Caffeine.newBuilder().maximumSize(100).build();
+		manager.registerCustomCache("customCache", customNativeCache);
+
+		// And: Dynamic cache created
+		manager.getCache("dynamicCache");
+
+		// When: Switch to static mode
+		manager.setCacheNames(List.of("staticCache"));
+
+		// Then: Custom cache preserved, dynamic cache removed
+		assertThat(manager.getCacheNames())
+				.contains("customCache", "staticCache")
+				.doesNotContain("dynamicCache");
+	}
+
+	@Test
+	void switchingBetweenDynamicAndStaticMode() {
+		CaffeineCacheManager manager = new CaffeineCacheManager();
+
+		// Dynamic → Static
+		manager.getCache("dynamicCache1");
+		manager.setCacheNames(List.of("staticCache1"));
+		assertThat(manager.getCacheNames()).containsExactly("staticCache1");
+
+		// Static → Dynamic
+		manager.setCacheNames(null); // Re-enable dynamic mode
+		manager.getCache("dynamicCache2");
+		assertThat(manager.getCacheNames()).contains("staticCache1", "dynamicCache2");
+
+		// Dynamic → Static again
+		manager.setCacheNames(List.of("staticCache2"));
+		assertThat(manager.getCacheNames()).containsExactly("staticCache2");
+	}
+
 	@Test
 	void cacheLoaderUseLoadingCache() {
 		CaffeineCacheManager cm = new CaffeineCacheManager("c1");