Influence of 17α-ethinylestradiol on DNA Methylation in Oysters

This repository includes a scientific report on an experiment designed to examine the impact of 17α-ethinylestradiol (a main component of birth control pills) on DNA methylation.

Files and Directories

• Gavery-Roberts-EE2.md - Scientific manuscript. format = markdown
• Gavery-Roberts-EE2.pdf - Scientific manuscript. format = PDF
• Table-2.md - Table of differentially methylated regions and annotations.
• tracks/oyster-EE2-DMR.gff - Generic Feature Format file with location of DMRs and hypo / hyper annotation.
• tracks/2013.11.21.A01_smoothed.wig - normalized and smoothed feature track (input versus input).
• tracks/2013.11.21.A02_smoothed.wig - normalized and smoothed feature track (EE2 vs control).
• tracks/2013.11.21.A03_smoothed.wig - normalized and smoothed feature track (EE2 vs control - dye swap).
• tracks/OID40453_probe_locations - location of probes from array across the genome.
• tracks/oyster-EE2-DMR.gff - Differentially methylated features.
• img/ - directory containing manuscript figures and table (image).
• misc/ - directory with RPubs backup, R code
• array-raw/ directory containing raw intensity files.
• array-description/ directory with details of array design, contains readme.md with file previews.

This work was supported in part by the National Science Foundation (NSF) under Grant Number 1158119 awarded to SR Roberts.