Who isolated epinephrine?
John Abel
Was it pure?
no
What form was it
in an impure state
Did someone produce it in a pure state?
yes
Who?
Jokichi Takamine
What was it used for?
for the acute treatment of asthma attacks
How was it used?
it was injected
Was there another way it was administered?
yes
How?
inhaled
What was the brand name?
Primatene Mis
When could someone buy it in the US?
until 2011
Who else offered the drug?
Parke Davis
What was it called?
Adrenalin
What else was epinephrine used to treat?
nasal congestion
Starting when?
1929
What did people want to learn more about?
the mechanism of chemical signalling
Of what chemicals?
adrenal extracts
Why?
they had a profound effect on many different tissue types
What did they want to make?
new drugs
What was an early usage of the chemicals?
blood pressure raising and vasoconstrictive effects