diff --git a/Makefile b/Makefile
index fd98ab5a60a6d..303c46e60f24d 100644
--- a/Makefile
+++ b/Makefile
@@ -579,7 +579,7 @@ CPPFLAGS := -Ithird_party/address_sorting/include $(CPPFLAGS)
 GRPC_ABSEIL_DEP = $(LIBDIR)/$(CONFIG)/libgrpc_abseil.a
 GRPC_ABSEIL_MERGE_LIBS = $(LIBDIR)/$(CONFIG)/libgrpc_abseil.a
 ifeq ($(HOST_IS_X86_64),true)
-ABSL_RANDOM_HWAES_FLAGS = -maes -msse4
+ABSL_RANDOM_HWAES_FLAGS = -maes
 else
 ABSL_RANDOM_HWAES_FLAGS =
 endif
diff --git a/templates/Makefile.template b/templates/Makefile.template
index 5afb36ce6a47f..7e47866b37e48 100644
--- a/templates/Makefile.template
+++ b/templates/Makefile.template
@@ -442,7 +442,7 @@
   GRPC_ABSEIL_DEP = $(LIBDIR)/$(CONFIG)/libgrpc_abseil.a
   GRPC_ABSEIL_MERGE_LIBS = $(LIBDIR)/$(CONFIG)/libgrpc_abseil.a
   ifeq ($(HOST_IS_X86_64),true)
-  ABSL_RANDOM_HWAES_FLAGS = -maes -msse4
+  ABSL_RANDOM_HWAES_FLAGS = -maes
   else
   ABSL_RANDOM_HWAES_FLAGS =
   endif