diff --git a/pkgs/development/lisp-modules/lisp-packages.nix b/pkgs/development/lisp-modules/lisp-packages.nix
index cb4ebba3ff49a9..69a4596c22f64f 100644
--- a/pkgs/development/lisp-modules/lisp-packages.nix
+++ b/pkgs/development/lisp-modules/lisp-packages.nix
@@ -150,6 +150,17 @@ let lispPackages = rec {
 
       # Prevent nyxt from trying to obtain dependencies as submodules
       makeFlags = [ "NYXT_SUBMODULES=false" ] ++ x.buildFlags or [];
+
+      patches = x.patches or [] ++ [
+        # Work around crash when opening _any_ URL
+        # https://github.com/atlas-engineer/nyxt/issues/1781
+        # https://github.com/NixOS/nixpkgs/issues/158005
+        (pkgs.fetchpatch {
+          name = "nyxt-webkit-disable-sandbox.patch";
+          url = "https://github.com/atlas-engineer/nyxt/commit/48ac0d8727f1ca1428188a1ab2c05b7be5f6cc51.patch";
+          sha256 = "0570mcfn5wmjha6jmfdgglp0w5b7rpfnv3flzn77clgbknwbxi0m";
+        })
+      ];
     };
 
     deps = with pkgs.lispPackages; [