diff --git a/CHANGELOG.md b/CHANGELOG.md
index ab3c73982..c2dc4fc19 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -11,10 +11,12 @@ Versioning](http://semver.org/spec/v2.0.0.html) except to the first release.
 ### Added
 
 * New types for MessagePack extensions compatible with go-option (#459).
+* Added `box.MustNew` wrapper for `box.New` without an error (#448).
 
 ### Changed
 
 * Required Go version is `1.24` now (#456).
+* `box.New` returns an error instead of panic (#448).
 
 ### Fixed
 
diff --git a/MIGRATION.md b/MIGRATION.md
index 54f4e3034..ea82c8815 100644
--- a/MIGRATION.md
+++ b/MIGRATION.md
@@ -9,6 +9,8 @@ TODO
 ### <a id="major-changes-v3">Major changes</a>
 
 * Required Go version is `1.24` now.
+* `box.New` returns an error instead of panic
+* Added `box.MustNew` wrapper for `box.New` without an error
 
 ## Migration from v1.x.x to v2.x.x
 
diff --git a/box/box.go b/box/box.go
index a4cc1780e..4341768cf 100644
--- a/box/box.go
+++ b/box/box.go
@@ -1,6 +1,8 @@
 package box
 
 import (
+	"errors"
+
 	"github.com/tarantool/go-tarantool/v3"
 )
 
@@ -11,16 +13,24 @@ type Box struct {
 }
 
 // New returns a new instance of the box structure, which implements the Box interface.
-func New(conn tarantool.Doer) *Box {
+func New(conn tarantool.Doer) (*Box, error) {
 	if conn == nil {
-		// Check if the provided Tarantool connection is nil, and if it is, panic with an error
-		// message. panic early helps to catch and fix nil pointer issues in the code.
-		panic("tarantool connection cannot be nil")
+		return nil, errors.New("tarantool connection cannot be nil")
 	}
 
 	return &Box{
 		conn: conn, // Assigns the provided Tarantool connection.
+	}, nil
+}
+
+// MustNew returns a new instance of the box structure, which implements the Box interface.
+// It panics if conn == nil.
+func MustNew(conn tarantool.Doer) *Box {
+	b, err := New(conn)
+	if err != nil {
+		panic(err)
 	}
+	return b
 }
 
 // Schema returns a new Schema instance, providing access to schema-related operations.
diff --git a/box/box_test.go b/box/box_test.go
index 59ceaf6e3..57d0d5526 100644
--- a/box/box_test.go
+++ b/box/box_test.go
@@ -15,8 +15,31 @@ import (
 func TestNew(t *testing.T) {
 	t.Parallel()
 
+	_, err := box.New(nil)
+	require.Error(t, err)
+}
+
+func TestMustNew(t *testing.T) {
+	t.Parallel()
+
 	// Create a box instance with a nil connection. This should lead to a panic.
-	require.Panics(t, func() { box.New(nil) })
+	require.Panics(t, func() { box.MustNew(nil) })
+}
+
+func TestMocked_BoxNew(t *testing.T) {
+	t.Parallel()
+
+	mock := test_helpers.NewMockDoer(t,
+		test_helpers.NewMockResponse(t, "valid"),
+	)
+
+	b, err := box.New(&mock)
+	require.NoError(t, err)
+	require.NotNil(t, b)
+
+	assert.Len(t, mock.Requests, 0)
+	b.Schema().User().Exists(box.NewInfoRequest().Ctx(), "")
+	require.Len(t, mock.Requests, 1)
 }
 
 func TestMocked_BoxInfo(t *testing.T) {
@@ -37,7 +60,7 @@ func TestMocked_BoxInfo(t *testing.T) {
 	mock := test_helpers.NewMockDoer(t,
 		test_helpers.NewMockResponse(t, data),
 	)
-	b := box.New(&mock)
+	b := box.MustNew(&mock)
 
 	info, err := b.Info()
 	require.NoError(t, err)
@@ -57,7 +80,7 @@ func TestMocked_BoxSchemaUserInfo(t *testing.T) {
 	mock := test_helpers.NewMockDoer(t,
 		test_helpers.NewMockResponse(t, data),
 	)
-	b := box.New(&mock)
+	b := box.MustNew(&mock)
 
 	privs, err := b.Schema().User().Info(context.Background(), "username")
 	require.NoError(t, err)
@@ -82,7 +105,7 @@ func TestMocked_BoxSessionSu(t *testing.T) {
 		test_helpers.NewMockResponse(t, []interface{}{}),
 		errors.New("user not found or supplied credentials are invalid"),
 	)
-	b := box.New(&mock)
+	b := box.MustNew(&mock)
 
 	err := b.Session().Su(context.Background(), "admin")
 	require.NoError(t, err)
diff --git a/box/example_test.go b/box/example_test.go
index fa65189a8..39474d8aa 100644
--- a/box/example_test.go
+++ b/box/example_test.go
@@ -45,7 +45,7 @@ func ExampleBox_Info() {
 
 	// Or use simple Box implementation.
 
-	b := box.New(client)
+	b := box.MustNew(client)
 
 	info, err := b.Info()
 	if err != nil {
@@ -88,7 +88,8 @@ func ExampleSchemaUser_Exists() {
 	}
 
 	// Or use simple User implementation.
-	b := box.New(client)
+	b := box.MustNew(client)
+
 	exists, err := b.Schema().User().Exists(ctx, "user")
 	if err != nil {
 		log.Fatalf("Failed get box schema user exists with error: %s", err)
@@ -120,7 +121,7 @@ func ExampleSchemaUser_Create() {
 	}
 
 	// Create SchemaUser.
-	schemaUser := box.New(client).Schema().User()
+	schemaUser := box.MustNew(client).Schema().User()
 
 	// Create a new user.
 	username := "new_user"
@@ -153,7 +154,7 @@ func ExampleSchemaUser_Drop() {
 	}
 
 	// Create SchemaUser.
-	schemaUser := box.New(client).Schema().User()
+	schemaUser := box.MustNew(client).Schema().User()
 
 	// Drop an existing user.
 	username := "new_user"
@@ -192,7 +193,7 @@ func ExampleSchemaUser_Password() {
 	}
 
 	// Create SchemaUser.
-	schemaUser := box.New(client).Schema().User()
+	schemaUser := box.MustNew(client).Schema().User()
 
 	// Get the password hash.
 	password := "my-password"
@@ -221,7 +222,7 @@ func ExampleSchemaUser_Info() {
 	}
 
 	// Create SchemaUser.
-	schemaUser := box.New(client).Schema().User()
+	schemaUser := box.MustNew(client).Schema().User()
 
 	info, err := schemaUser.Info(ctx, "test")
 	if err != nil {
diff --git a/box/session_test.go b/box/session_test.go
index 39b80d1d4..188360251 100644
--- a/box/session_test.go
+++ b/box/session_test.go
@@ -10,7 +10,7 @@ import (
 )
 
 func TestBox_Session(t *testing.T) {
-	b := box.New(th.Ptr(th.NewMockDoer(t)))
+	b := box.MustNew(th.Ptr(th.NewMockDoer(t)))
 	require.NotNil(t, b.Session())
 }
 
diff --git a/box/tarantool_test.go b/box/tarantool_test.go
index 4244a98e9..ae47932d8 100644
--- a/box/tarantool_test.go
+++ b/box/tarantool_test.go
@@ -48,7 +48,9 @@ func TestBox_Sugar_Info(t *testing.T) {
 	conn, err := tarantool.Connect(ctx, dialer, tarantool.Opts{})
 	require.NoError(t, err)
 
-	info, err := box.New(conn).Info()
+	b := box.MustNew(conn)
+
+	info, err := b.Info()
 	require.NoError(t, err)
 
 	validateInfo(t, info)
@@ -83,7 +85,7 @@ func TestBox_Sugar_Schema_UserCreate_NoError(t *testing.T) {
 	conn, err := tarantool.Connect(ctx, dialer, tarantool.Opts{})
 	require.NoError(t, err)
 
-	b := box.New(conn)
+	b := box.MustNew(conn)
 
 	// Create new user.
 	err = b.Schema().User().Create(ctx, username, box.UserCreateOptions{Password: password})
@@ -103,7 +105,7 @@ func TestBox_Sugar_Schema_UserCreate_CanConnectWithNewCred(t *testing.T) {
 	conn, err := tarantool.Connect(ctx, dialer, tarantool.Opts{})
 	require.NoError(t, err)
 
-	b := box.New(conn)
+	b := box.MustNew(conn)
 
 	// Create new user.
 	err = b.Schema().User().Create(ctx, username, box.UserCreateOptions{Password: password})
@@ -137,7 +139,7 @@ func TestBox_Sugar_Schema_UserCreate_AlreadyExists(t *testing.T) {
 	conn, err := tarantool.Connect(ctx, dialer, tarantool.Opts{})
 	require.NoError(t, err)
 
-	b := box.New(conn)
+	b := box.MustNew(conn)
 
 	// Create new user.
 	err = b.Schema().User().Create(ctx, username, box.UserCreateOptions{Password: password})
@@ -167,7 +169,7 @@ func TestBox_Sugar_Schema_UserCreate_ExistsTrue(t *testing.T) {
 	conn, err := tarantool.Connect(ctx, dialer, tarantool.Opts{})
 	require.NoError(t, err)
 
-	b := box.New(conn)
+	b := box.MustNew(conn)
 
 	// Create new user.
 	err = b.Schema().User().Create(ctx, username, box.UserCreateOptions{Password: password})
@@ -193,7 +195,7 @@ func TestBox_Sugar_Schema_UserCreate_IfNotExistsNoErr(t *testing.T) {
 	conn, err := tarantool.Connect(ctx, dialer, tarantool.Opts{})
 	require.NoError(t, err)
 
-	b := box.New(conn)
+	b := box.MustNew(conn)
 
 	// Create new user.
 	err = b.Schema().User().Create(ctx, username, box.UserCreateOptions{Password: password})
@@ -217,7 +219,7 @@ func TestBox_Sugar_Schema_UserPassword(t *testing.T) {
 	conn, err := tarantool.Connect(ctx, dialer, tarantool.Opts{})
 	require.NoError(t, err)
 
-	b := box.New(conn)
+	b := box.MustNew(conn)
 
 	// Require password hash.
 	hash, err := b.Schema().User().Password(ctx, password)
@@ -236,7 +238,7 @@ func TestBox_Sugar_Schema_UserDrop_AfterCreate(t *testing.T) {
 	conn, err := tarantool.Connect(ctx, dialer, tarantool.Opts{})
 	require.NoError(t, err)
 
-	b := box.New(conn)
+	b := box.MustNew(conn)
 
 	// Create new user
 	err = b.Schema().User().Create(ctx, username, box.UserCreateOptions{Password: password})
@@ -258,7 +260,7 @@ func TestBox_Sugar_Schema_UserDrop_DoubleDrop(t *testing.T) {
 	conn, err := tarantool.Connect(ctx, dialer, tarantool.Opts{})
 	require.NoError(t, err)
 
-	b := box.New(conn)
+	b := box.MustNew(conn)
 
 	// Create new user
 	err = b.Schema().User().Create(ctx, username, box.UserCreateOptions{Password: password})
@@ -286,7 +288,7 @@ func TestBox_Sugar_Schema_UserDrop_UnknownUser(t *testing.T) {
 	conn, err := tarantool.Connect(ctx, dialer, tarantool.Opts{})
 	require.NoError(t, err)
 
-	b := box.New(conn)
+	b := box.MustNew(conn)
 
 	// Require error cause user not exists
 	err = b.Schema().User().Drop(ctx, "some_strange_not_existing_name", box.UserDropOptions{})
@@ -305,7 +307,7 @@ func TestSchemaUser_Passwd_NotFound(t *testing.T) {
 	conn, err := tarantool.Connect(ctx, dialer, tarantool.Opts{})
 	require.NoError(t, err)
 
-	b := box.New(conn)
+	b := box.MustNew(conn)
 
 	err = b.Schema().User().Passwd(ctx, "not-exists-passwd", "new_password")
 	require.Error(t, err)
@@ -329,7 +331,7 @@ func TestSchemaUser_Passwd_Ok(t *testing.T) {
 	conn, err := tarantool.Connect(ctx, dialer, tarantool.Opts{})
 	require.NoError(t, err)
 
-	b := box.New(conn)
+	b := box.MustNew(conn)
 
 	// New user change password and connect
 
@@ -367,7 +369,7 @@ func TestSchemaUser_Passwd_WithoutGrants(t *testing.T) {
 	conn, err := tarantool.Connect(ctx, dialer, tarantool.Opts{})
 	require.NoError(t, err)
 
-	b := box.New(conn)
+	b := box.MustNew(conn)
 
 	err = b.Schema().User().Create(ctx, username,
 		box.UserCreateOptions{Password: startPassword, IfNotExists: true})
@@ -381,7 +383,8 @@ func TestSchemaUser_Passwd_WithoutGrants(t *testing.T) {
 	require.NoError(t, err)
 	require.NotNil(t, conn2Fail)
 
-	bFail := box.New(conn2Fail)
+	bFail := box.MustNew(conn2Fail)
+
 	// can't change self user password without grants
 	err = bFail.Schema().User().Passwd(ctx, endPassword)
 	require.Error(t, err)
@@ -401,7 +404,7 @@ func TestSchemaUser_Info_TestUserCorrect(t *testing.T) {
 	conn, err := tarantool.Connect(ctx, dialer, tarantool.Opts{})
 	require.NoError(t, err)
 
-	b := box.New(conn)
+	b := box.MustNew(conn)
 
 	privileges, err := b.Schema().User().Info(ctx, dialer.User)
 	require.NoError(t, err)
@@ -418,7 +421,7 @@ func TestSchemaUser_Info_NonExistsUser(t *testing.T) {
 	conn, err := tarantool.Connect(ctx, dialer, tarantool.Opts{})
 	require.NoError(t, err)
 
-	b := box.New(conn)
+	b := box.MustNew(conn)
 
 	privileges, err := b.Schema().User().Info(ctx, "non-existing")
 	require.Error(t, err)
@@ -438,7 +441,7 @@ func TestBox_Sugar_Schema_UserGrant_NoSu(t *testing.T) {
 	conn, err := tarantool.Connect(ctx, dialer, tarantool.Opts{})
 	require.NoError(t, err)
 
-	b := box.New(conn)
+	b := box.MustNew(conn)
 
 	err = b.Schema().User().Create(ctx, username, box.UserCreateOptions{Password: password})
 	require.NoError(t, err)
@@ -471,7 +474,7 @@ func TestBox_Sugar_Schema_UserGrant_WithSu(t *testing.T) {
 	conn, err := tarantool.Connect(ctx, dialer, tarantool.Opts{})
 	require.NoError(t, err)
 
-	b := box.New(conn)
+	b := box.MustNew(conn)
 
 	err = b.Schema().User().Create(ctx, username, box.UserCreateOptions{Password: password})
 	require.NoError(t, err)
@@ -521,7 +524,7 @@ func TestSchemaUser_Revoke_WithoutSu(t *testing.T) {
 	conn, err := tarantool.Connect(ctx, dialer, tarantool.Opts{})
 	require.NoError(t, err)
 
-	b := box.New(conn)
+	b := box.MustNew(conn)
 
 	err = b.Schema().User().Create(ctx, username, box.UserCreateOptions{Password: password})
 	require.NoError(t, err)
@@ -555,7 +558,7 @@ func TestSchemaUser_Revoke_WithSu(t *testing.T) {
 	conn, err := tarantool.Connect(ctx, dialer, tarantool.Opts{})
 	require.NoError(t, err)
 
-	b := box.New(conn)
+	b := box.MustNew(conn)
 
 	err = b.Schema().User().Create(ctx, username, box.UserCreateOptions{Password: password})
 	require.NoError(t, err)
@@ -603,7 +606,7 @@ func TestSchemaUser_Revoke_NonExistsPermission(t *testing.T) {
 	conn, err := tarantool.Connect(ctx, dialer, tarantool.Opts{})
 	require.NoError(t, err)
 
-	b := box.New(conn)
+	b := box.MustNew(conn)
 
 	err = b.Schema().User().Create(ctx, username, box.UserCreateOptions{Password: password})
 	require.NoError(t, err)
@@ -639,7 +642,7 @@ func TestSession_Su_AdminPermissions(t *testing.T) {
 	conn, err := tarantool.Connect(ctx, dialer, tarantool.Opts{})
 	require.NoError(t, err)
 
-	b := box.New(conn)
+	b := box.MustNew(conn)
 
 	err = b.Session().Su(ctx, "admin")
 	require.NoError(t, err)
@@ -652,7 +655,8 @@ func cleanupUser(username string) {
 		log.Fatal(err)
 	}
 
-	b := box.New(conn)
+	b := box.MustNew(conn)
+
 	err = b.Schema().User().Drop(ctx, username, box.UserDropOptions{})
 	if err != nil {
 		log.Fatal(err)