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University of California, Los Angeles
615 Charles E Young Dr S
BSRB Rm 454
Los Angeles, CA 90095
Email: iam [at] tamasnagy.com
Website: https://tamasnagy.com
2023--- Postdoctoral Scholar, Neurology, Univ. of
California, Los Angeles\medskip
\ \ \ \ \ \ \ Topic: "How do Satellite Cells Count? Information Processing in Motile Cellular Collectives"
\ \ \ \ \ Advisor: Thomas A. Rando, M.D., Ph.D.
2024 Course Attendee, Physiology: Modern Cell Biology Using Microscopic, Biochemical and Computational Approaches, Marine Biological Laboratory, Woods Hole MA.\medskip
\ \ \ \ \ Course Directors: Amy Gladfelter, Ph.D., Cliff Braggwynne, Ph.D.
\ \ \ \ \ Rotation Advisors: Stephan Grill, Ph.D., Manu Prakash, Ph.D.
2015---2023 Ph.D., Biomedical Informatics, University of
California, San Francisco\medskip
\ \ \ \ \ Thesis: “Neutrophils actively swell to potentiate rapid migration”
\ \ \ \ \ Advisor: Orion D. Weiner, Ph.D.
2011---2015 B.S. in Chemistry, B.S. in Mathematical Sci, University of Kentucky, Lexington
Cellular Decision Making; Collective Intelligence; Nonequilibrium Dynamics; Information Propagation; Tissue Regeneration; Cellular Motility
2024--- LLHF Fellowship Grant, Larry L. Hillblom Foundation, Sonoma, CA ($225,000)
2017---2020 Moritz-Heyman Discovery Fellow, University of California, San Francisco
2015---2020 NSF Graduate Research Fellow, National Science Foundation (~$110,000)
2013 AMGEN/CRSB Fellow w/Jennifer Doudna, University of California, Berkeley
2011---2015 Otis A. Singletary Scholar, University of Kentucky (Tuition, Board, & stipend)
De Belly, H., Gallen, A.F., Strickland, E., Estrada, D.C., Zager, P.J., Nagy, T. L., Burkhardt, J.K., Turlier, H., Weiner, O.D. (2025). Long range mutual activation establishes Rho and Rac polarity during cell migration. bioRxiv. https://doi.org/10.1101/2024.10.01.616161.
\ \ \ \ \ \ \ \ \ \ Preprint (Submitted).
Nagy, T.L., Strickland, E., and Weiner, O.D. (2024). Neutrophils actively swell to potentiate
rapid migration. Elife 12. https://doi.org/10.7554/eLife.90551.
\ \ \ \ \ \ \ \ \ \ Editorial assessment: Fundamental and compelling
Graziano, B. R., Town, J. P., Sitarska, E., Nagy, T. L., Fošnarič, M., Penič, S., Iglič, A., Kralj-Iglič, V., Gov, N. S., Diz-Muñoz, A., & Weiner, O. D. (2019). Cell confinement reveals a branched-actin independent circuit for neutrophil polarity. PLoS Biology, 17(10), e3000457. https://doi.org/10.1371/journal.pbio.3000457
Saha, S., Nagy, T. L. & Weiner, O. D. Joining forces: crosstalk between biochemical signalling and physical forces orchestrates cellular polarity and dynamics. Philos. Trans. R. Soc. Lond. B Biol. Sci. 373, (2018). https://doi.org/10.1098/rstb.2017.0145
Mavor, D., Barlow, K.A.,..., Nagy, T.L.,..., et al. (2018). Extending chemical perturbations of the ubiquitin fitness landscape in a classroom setting reveals new constraints on sequence tolerance. Biol. Open 7. https://doi.org/10.1242/bio.036103.
Nagy, T. & Kampmann, M. CRISPulator: a discrete simulation tool for pooled genetic screens. BMC Bioinformatics 18, 347 (2017). https://doi.org/10.1186/s12859-017-1759-9
Webb, S., Nagy, T., Moseley, H., Fried, M. & Dutch, R. E. Hendra virus fusion protein transmembrane domain contributes to pre-fusion protein stability. J. Biol. Chem. (2017). https://doi.org/10.1074/jbc.M117.777235
2025--- Mentor to Samuel Adubofour (Undergraduate COMPASS student)
2024---2025 Mentor to Yutzil Herrera (Undergraduate COMPASS student)
Spring 2025 Mentor to Candace Wang (UCLA MSTP Student)
Winter 2022 Rotation Advisor to Sneha Rao (UCSF DSCB Student)
Fall 2018 Rotation Advisor to Evelyn Strickland (UCSF Biophysics Student)
2025 Poster "How do Muscle Stem Cells Count? Information Propagation in Motile Cellular Collectives", Gordon Research Conference on Directed Cell Migration, Barga, Italy
2023 Talk "Neutrophils actively swell to potentiate their migration" American Society for Cell Biology Meeting, Boston, MA
2023 Poster "Immune cells actively increase their volumes to facilitate migration"
UCSF Cardiovascular Research Institute Departmental Retreat, Santa Cruz, CA
\ \ \ \ \ \ \ \ \ \ **Best Poster Award**
2023 Poster "Immune cells actively increase their volumes to facilitate migration" Gordon Research Conference on Directed Cell Migration, Galveston, TX
2022 Poster "Dissecting the role of regulatory volume changes in neutrophil chemotaxis"
66th Annual Meeting of the Biophysical Society, San Francisco, CA
\ \ \ \ \ \ \ \ \ \ **Best Poster Award**
2020 Talk "Leveraging Julia for Data Science", invited speaker, 2020 Computational Biology Skills Seminar, UC Berkeley, remote
2019 Poster "Dissecting the mechanistic basis of the chemoattractant-induced volume increase in neutrophils", 2019 Gordon Research Conference on Directed Cell Migration, Galveston, TX
2018 Poster "Dissecting the mechanistic basis of the chemoattractant-induced volume increase in neutrophils", 2018 Ion Channels & Immunity Symposium, NYU Langone Health, New York City, NY
2018 Poster "Active control of cell volume during immune cell migration", 2018 Training Grantees Meeting, National Institute of Biomedical Imaging and Bioengineering, Bethesda, MD
2016 Talk "Leveraging CRISPR for Precision Biology", Workshop with Jacob Corn and Martin Kampmann, American Society for Cell Biology Annual Meeting, San Francisco, CA
2013 Talk "Engineered CRISPR/Cas-based System for RNA-guided, Tag-less, Spatiotemporal Imaging of Endogeneous RNA," AMGEN symposium, Berkeley, CA
I regularly develop and release open-source software as part of my work, some of my most substantial packages are highlighted below
TiffImages.jl: A high performance, extensible reader and writer for TIFF images in JuliaOMETIFF.jl: Read and interact with high-dimensional imagesCrispulator.jl: Simulation tool for designing pooled CRISPR screens
2023---2025 Co-Chair, 2025 Directed Cell Migration Gordon Research Seminar
2017—--2019 iPQB Graduate Student Admissions Interviewer and Committee Member, UCSF
2018 Teaching Assistant, Algorithms, University of California, San Francisco
2017 Teaching Assistant, Algorithms, University of California, San Francisco
\ \ \ \ \ \ \ \ \ \ **UCSF Graduate Division Teaching Award**
2014 Teaching Assistant, Organic Chemistry II, University of Kentucky
2013 Teaching Assistant, Organic Chemistry I, University of Kentucky
2013---2014 Public Relations, Society for the Promotion of Undergraduate Research (SPUR)
Fred Chang, UCSF, fred.chang [at] ucsf.edu
Amy Gladfelter, Duke University, amy.gladfelter [at] duke.edu
Stephan Grill, Max Planck Institute of Molecular Cell Biology and Genetics, grill [at] mpi-cbg.de
Martin Kampmann, UCSF, martin.kampmann [at] ucsf.edu
Thomas A Rando, UCLA, TRando [at] mednet.ucla.edu
Orion Weiner, UCSF, orion.weiner [at] ucsf.edu