diff --git a/README.md b/README.md
index d3e6a944..03e76030 100644
--- a/README.md
+++ b/README.md
@@ -379,6 +379,17 @@ By overriding the provided [`AbstractSnapshotExtension`](https://github.com/toph
 
 See examples of how syrupy can be used and extended in the [test examples](https://github.com/tophat/syrupy/tree/main/tests/examples).
 
+#### Overriding defaults
+
+It is possible to override `include`, `exclude`, `matchers` and `extension_class` on a more global level just once, 
+instead of every time per test. By default, after every assertion the modified values per snapshot assert are reverted
+to their default values. However, it is possible to override those default values with ones you would like persisted, 
+which will be treated as the new defaults.
+
+To achieve that you can use `snapshot.with_defaults`, which will create new instance of `SnapshotAssertion` with the provided values.
+
+`snapshot.use_extension` is retained for compatibility. However, it is limited to only overriding the default extension class.
+
 #### JSONSnapshotExtension
 
 This extension can be useful when testing API responses, or when you have to deal with long dictionaries that are cumbersome to validate inside a test. For example:
@@ -390,7 +401,8 @@ from syrupy.extensions.json import JSONSnapshotExtension
 
 @pytest.fixture
 def snapshot_json(snapshot):
-    return snapshot.use_extension(JSONSnapshotExtension)
+    return snapshot.with_defaults(extension_class=JSONSnapshotExtension)
+    # or return snapshot.use_extension(JSONSnapshotExtension)
 
 
 def test_api_call(client, snapshot_json):
@@ -455,6 +467,7 @@ The generated snapshot:
 
 ### Extending Syrupy
 
+- [Custom defaults](https://github.com/tophat/syrupy/tree/main/tests/examples/test_custom_defaults.py)
 - [Custom snapshot directory 1](https://github.com/tophat/syrupy/tree/main/tests/examples/test_custom_snapshot_directory.py)
 - [Custom snapshot directory 2](https://github.com/tophat/syrupy/tree/main/tests/examples/test_custom_snapshot_directory_2.py)
 - [Custom snapshot name](https://github.com/tophat/syrupy/tree/main/tests/examples/test_custom_snapshot_name.py)
diff --git a/src/syrupy/assertion.py b/src/syrupy/assertion.py
index a3a7c0f8..6bdb4fcf 100644
--- a/src/syrupy/assertion.py
+++ b/src/syrupy/assertion.py
@@ -60,6 +60,9 @@ class SnapshotAssertion:
     extension_class: Type["AbstractSyrupyExtension"]
     test_location: "PyTestLocation"
     update_snapshots: bool
+    include: Optional["PropertyFilter"] = None
+    exclude: Optional["PropertyFilter"] = None
+    matcher: Optional["PropertyMatcher"] = None
 
     _exclude: Optional["PropertyFilter"] = field(
         init=False,
@@ -99,6 +102,9 @@ class SnapshotAssertion:
 
     def __post_init__(self) -> None:
         self.session.register_request(self)
+        self._include = self.include
+        self._exclude = self.exclude
+        self._matcher = self.matcher
 
     def __init_extension(
         self, extension_class: Type["AbstractSyrupyExtension"]
@@ -165,20 +171,37 @@ def _matcher(**kwargs: Any) -> Optional["SerializableData"]:
 
         return _matcher
 
-    def use_extension(
-        self, extension_class: Optional[Type["AbstractSyrupyExtension"]] = None
+    def with_defaults(
+        self,
+        *,
+        exclude: Optional["PropertyFilter"] = None,
+        include: Optional["PropertyFilter"] = None,
+        matcher: Optional["PropertyMatcher"] = None,
+        extension_class: Optional[Type["AbstractSyrupyExtension"]] = None,
     ) -> "SnapshotAssertion":
         """
-        Creates a new snapshot assertion fixture with the same options but using
-        specified extension class. This does not preserve assertion index or state.
+        Create new snapshot assertion fixture with provided values. This preserves
+        provided values between assertions.
         """
         return self.__class__(
+            matcher=matcher or self.matcher,
+            include=include or self.include,
+            exclude=exclude or self.exclude,
             update_snapshots=self.update_snapshots,
             test_location=self.test_location,
             extension_class=extension_class or self.extension_class,
             session=self.session,
         )
 
+    def use_extension(
+        self, extension_class: Optional[Type["AbstractSyrupyExtension"]] = None
+    ) -> "SnapshotAssertion":
+        """
+        Create new snapshot assertion fixture with the same options but using
+        specified extension class. This does not preserve assertion index or state.
+        """
+        return self.with_defaults(extension_class=extension_class)
+
     def assert_match(self, data: "SerializableData") -> None:
         assert self == data
 
diff --git a/tests/examples/__snapshots__/test_custom_defaults.ambr b/tests/examples/__snapshots__/test_custom_defaults.ambr
new file mode 100644
index 00000000..bf689f44
--- /dev/null
+++ b/tests/examples/__snapshots__/test_custom_defaults.ambr
@@ -0,0 +1,23 @@
+# serializer version: 1
+# name: test_asserting_multiple_times
+  dict({
+    'excluded': 'value',
+    'my-field': str,
+  })
+# ---
+# name: test_asserting_multiple_times.1
+  dict({
+    'excluded': 'value',
+    'my-field': int,
+  })
+# ---
+# name: test_asserting_multiple_times_chained
+  dict({
+    'my-field': str,
+  })
+# ---
+# name: test_asserting_multiple_times_chained.1
+  dict({
+    'my-field': int,
+  })
+# ---
diff --git a/tests/examples/__snapshots__/test_custom_defaults/test_asserting_multiple_times_chained_json.1.json b/tests/examples/__snapshots__/test_custom_defaults/test_asserting_multiple_times_chained_json.1.json
new file mode 100644
index 00000000..39e96ded
--- /dev/null
+++ b/tests/examples/__snapshots__/test_custom_defaults/test_asserting_multiple_times_chained_json.1.json
@@ -0,0 +1,3 @@
+{
+  "my-field": "int"
+}
diff --git a/tests/examples/__snapshots__/test_custom_defaults/test_asserting_multiple_times_chained_json.json b/tests/examples/__snapshots__/test_custom_defaults/test_asserting_multiple_times_chained_json.json
new file mode 100644
index 00000000..c55400a5
--- /dev/null
+++ b/tests/examples/__snapshots__/test_custom_defaults/test_asserting_multiple_times_chained_json.json
@@ -0,0 +1,3 @@
+{
+  "my-field": "str"
+}
diff --git a/tests/examples/test_custom_defaults.py b/tests/examples/test_custom_defaults.py
new file mode 100644
index 00000000..43bf8f37
--- /dev/null
+++ b/tests/examples/test_custom_defaults.py
@@ -0,0 +1,42 @@
+"""Example: Custom snapshot defaults
+
+Here we modify snapshot defaults globally, instead of per assert.
+This gives the ability to modify the snapshot functionality to your hearts content
+and then simply re-use them, without having to pass those defaults to every assert.
+Especially useful if there's a lot of tests that need to modify the default behaviour.
+"""
+import pytest
+
+from syrupy.extensions.json import JSONSnapshotExtension
+from syrupy.filters import paths
+from syrupy.matchers import path_type
+
+
+@pytest.fixture
+def snapshot_matcher(snapshot):
+    return snapshot.with_defaults(matcher=path_type(mapping={"my-field": (str, int)}))
+
+
+@pytest.fixture
+def snapshot_exclude(snapshot_matcher):
+    return snapshot_matcher.with_defaults(exclude=paths("excluded"))
+
+
+@pytest.fixture
+def snapshot_json(snapshot_exclude):
+    return snapshot_exclude.with_defaults(extension_class=JSONSnapshotExtension)
+
+
+def test_asserting_multiple_times(snapshot_matcher):
+    assert {"my-field": "my-string", "excluded": "value"} == snapshot_matcher
+    assert {"my-field": 12345, "excluded": "value"} == snapshot_matcher
+
+
+def test_asserting_multiple_times_chained(snapshot_exclude):
+    assert {"my-field": "my-string", "excluded": "value"} == snapshot_exclude
+    assert {"my-field": 12345, "excluded": "value"} == snapshot_exclude
+
+
+def test_asserting_multiple_times_chained_json(snapshot_json):
+    assert {"my-field": "my-string", "excluded": "value"} == snapshot_json
+    assert {"my-field": 12345, "excluded": "value"} == snapshot_json