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biology
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New PROTACs dataset
Describe the problem
PROTACs are a class of therapeutics that flag target proteins to a cell's waste disposal system, instead of the traditional binding to targets. It has been very promising due to its ability to tackle undruggable targets. However, problems still exist, such as designing the PROTACs, measure the degradability, understand the mechanism. A recent paper https://www.biorxiv.org
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Is this on anyone's radar? I know it's a simple item to add directly
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Describe the bug
LocalOtsuThreshold
should return a binary mask as np.ndarray
, like its "sibling" OtsuThreshold
- We should not apply
np_to_pil
before returning, butthreshold_to_mask
(likeOtsuThreshold
) - The docstrings of
LocalOtsuThreshold
andlocal_otsu_threshold
are different, while they should be the same. - Type hints need to be fixed as well to reflect the new
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so that in multicellular the player can have special "smelling" cells and they would work. Right now the guidance lines probably only read the chemoreceptors from the main player cell. Should be relatively simple to change it to look at also other cells in the player's colony if you ask the colony lead cell what chemoreceptors it has.