diff --git a/docs/changelog/1374.bugfix.rst b/docs/changelog/1374.bugfix.rst
new file mode 100644
index 000000000..4c052109f
--- /dev/null
+++ b/docs/changelog/1374.bugfix.rst
@@ -0,0 +1 @@
+Fix ``PythonSpec`` detection of ``python3.10`` - by :user:`asottile`
diff --git a/docs/changelog/1377.fix.rst b/docs/changelog/1377.bugfix.rst
similarity index 100%
rename from docs/changelog/1377.fix.rst
rename to docs/changelog/1377.bugfix.rst
diff --git a/src/tox/interpreters/py_spec.py b/src/tox/interpreters/py_spec.py
index 104af4177..04c062e63 100644
--- a/src/tox/interpreters/py_spec.py
+++ b/src/tox/interpreters/py_spec.py
@@ -53,7 +53,7 @@ def from_name(cls, base_python):
         if os.path.isabs(base_python):
             path = base_python
         else:
-            match = re.match(r"(python|pypy|jython)(\d)?(?:\.(\d))?(-(32|64))?", base_python)
+            match = re.match(r"(python|pypy|jython)(\d)?(?:\.(\d+))?(-(32|64))?", base_python)
             if match:
                 groups = match.groups()
                 name = groups[0]
diff --git a/tests/unit/interpreters/test_py_spec.py b/tests/unit/interpreters/test_py_spec.py
new file mode 100644
index 000000000..48024afde
--- /dev/null
+++ b/tests/unit/interpreters/test_py_spec.py
@@ -0,0 +1,6 @@
+from tox.interpreters.py_spec import PythonSpec
+
+
+def test_py_3_10():
+    spec = PythonSpec.from_name("python3.10")
+    assert (spec.major, spec.minor) == (3, 10)