Pathway activation model for personalized prediction of drug synergy
run.R shows a pipeline to generate PAS features, train the model and get predictions with a toy dataset in data.
NOTE: DIPx is for research use only, please do not use results of DIPx for any practical medical treatment decisions.
If you are using DIPx in your research, please cite:
Trac Quang Thinh, Huang Yue, Erkers Tom, Östling Päivi, Bohlin Anna, Österroos Albin,
Vesterlund Mattias, Jafari Rozbeh, Siavelis Ioannis, Bäckvall Helena, Kiviluoto Santeri,
Orre Lukas M, Rantalainen Mattias, Lehtiö Janne, Lehmann Sören, Kallioniemi Olli,
Pawitan Yudi, Vu Trung Nghia (2024)
Pathway activation model for personalized prediction of drug synergy eLife 13:RP100071
https://doi.org/10.7554/eLife.100071.3