Pathway activation model for personalized prediction of drug synergy
run.R shows a pipeline to generate PAS features, train the model and get predictions with a toy dataset in data.
NOTE: DIPx is for research use only, please do not use results of DIPx for any practical medical treatment decisions.
If you are using DIPx in your research, please cite:
Quang Thinh Trac*, Yue Huang*, Tom Erkers, Päivi Östling, Anna Bohlin, Albin Österroos, Mattias Vesterlund, Rozbeh Jafari, Ioannis Siavelis, Helena Bäckvall, Santeri Kiviluoto, Lukas M. Orre, Mattias Rantalainen, Janne Lehtiö, Sören Lehmann, Olli Kallioniemi, Yudi Pawitan & Trung Nghia Vu.
Pathway activation model for personalized prediction of drug synergy.
*: Authors contributed equally to this work.