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Tenet

Characterize known targets in signaling networks using topological features A network-based approach that characterizes known targets in signaling networks using topological features. TENET first computes a set of topological features and then leverages a support vector machine-based approach to identify predictive topological features that characterizes known targets. A characterization model is generated and it specifies which topological features are important for discriminating the targets and how these features should be combined to quantify the likelihood of a node being a target.

Instructions:

  1. Download and save all files you see here to a folder called "network_lib" in the C directory "C:"
  2. Unzip the follwing files: CuiNetworkData.zip, svmTraining.zip and timeseries.zip
  3. Follow the TENET User Guide.pdf for rest of installation and usage instructions.

Location of .jar:

  1. TENET.jar is found in the release (https://github.com/trove2017/Tenet/releases)

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Characterize known targets in signaling networks using topological features

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