diff --git a/scipy/stats/tests/test_distributions.py b/scipy/stats/tests/test_distributions.py
index 184f3e8bc28d..cb2a52e0c7cb 100644
--- a/scipy/stats/tests/test_distributions.py
+++ b/scipy/stats/tests/test_distributions.py
@@ -7,6 +7,7 @@
 import pickle
 import os
 import json
+import platform
 
 from numpy.testing import (assert_equal, assert_array_equal,
                            assert_almost_equal, assert_array_almost_equal,
@@ -37,6 +38,10 @@
 # python -OO strips docstrings
 DOCSTRINGS_STRIPPED = sys.flags.optimize > 1
 
+# Failing on macOS 11, Intel CPUs. See gh-14901
+MACOS_INTEL = (sys.platform == 'darwin') and (platform.machine() == 'x86_64')
+
+
 # distributions to skip while testing the fix for the support method
 # introduced in gh-13294. These distributions are skipped as they
 # always return a non-nan support for every parametrization.
@@ -2840,6 +2845,7 @@ def test_fit_duplicated_fixed_parameter(self):
         x = [0.1, 0.5, 0.6]
         assert_raises(ValueError, stats.beta.fit, x, fa=0.5, fix_a=0.5)
 
+    @pytest.mark.skipif(MACOS_INTEL, reason="Overflow, see gh-14901")
     def test_issue_12635(self):
         # Confirm that Boost's beta distribution resolves gh-12635.
         # Check against R:
@@ -2851,6 +2857,7 @@ def test_issue_12635(self):
         p, a, b = 0.9999999999997369, 75.0, 66334470.0
         assert_allclose(stats.beta.ppf(p, a, b), 2.343620802982393e-06)
 
+    @pytest.mark.skipif(MACOS_INTEL, reason="Overflow, see gh-14901")
     def test_issue_12794(self):
         # Confirm that Boost's beta distribution resolves gh-12794.
         # Check against R.
@@ -2868,6 +2875,7 @@ def test_issue_12794(self):
         res = stats.beta.sf(inv, count_list + 1, 100000 - count_list)
         assert_allclose(res, p)
 
+    @pytest.mark.skipif(MACOS_INTEL, reason="Overflow, see gh-14901")
     def test_issue_12796(self):
         # Confirm that Boost's beta distribution succeeds in the case
         # of gh-12796