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The original Daaaaave algorithm is described in Lee D, Smallbone K, Dunn WB, Murabito E, Winder CL, Kell DB, Mendes P, Swainston N (2012) "Improving metabolic flux predictions using absolute gene expression data" BMC Syst Biol 6:73 http://dx.doi.org/10.1186/1752-0509-6-73 The algorithm was originally implemented in MatLab, but is now also available in python. This version was released on 19 May 14 and is available at http://github.com/u003f/daaaaave/releases/tag/original We are developing all aspects of the algorithm.