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Brian Druker

  • 100 years ago there was little medical knowledge
  • "If the cause has been discovered, then there is hope for a cure"
  • Cancer causes 1 in 4 deaths in our country
  • Over the last century we have developed a theory about what causes cancer, the 'Genetic Theory'

Glevac

  • For 30 years we thought that the only way to defeat cancer was to kill the cancer cells
  • Developing a drug is really expensive (500mil - 1Bil) and a 1 in 10 chance of being successful
  • Cancer is like a thermostat that is 'stuck on'
  • Glevac - targeted the cause of the growth of the leukemia

    • Thousands of places where a cell can break and Glevac targeted only one of these
    • Glevac works for 10 different cancers
  • Figure out why and how a cancer is broken and fix the broken part

    • Do this by sequencing a cancer's DNA and look for broken parts
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