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UGENE is free open-source cross-platform bioinformatics software
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Building UGENE


Make sure the Qt (>= 5.3.2) development libraries are installed:

  • Ubuntu >=14.04: sudo apt-get install qt5-default qttools5-dev-tools qtscript5-dev libqt5svg5-dev libqt5webkit5-dev
  • Ubuntu 12.04:
    • Download and install Qt 5.5.1:
    • Set the system variable: export PATH=$PATH:~/Qt5.5.1/5.5/gcc_64/bin
    • sudo apt-get install g++ libgl1-mesa-dev libglu1-mesa-dev
  • Fedora: sudo yum install qt5-qtscript-devel qt5-qtbase-devel qt5-qtsvg-devel qt5-linguist qt5-qtwebkit-devel gcc-c++ redhat-rpm-config mesa-libGLU-devel
  • Arch Linux: sudo pacman -S qt
  • Mac OS X: download from Qt official site (
  • Windows: download from Qt official site (

For Windows users:

To build with devenv (Visual Studio)

  1. qmake -r -tp vc 1.1. add "CONFIG+=x64" to qmake command for 64-bit build
  2. open ugene.sln from Visual Studio or run devenv.exe ugene.sln /Build from MSVC command line

To build with nmake.exe:

  1. qmake -r 1.1. add "CONFIG+=x64" to qmake command for 64-bit build
  2. run nmake, nmake debug or nmake release to build UGENE

Also you need to add "libeay.dll" and "ssleay.dll" from OpenSSL ToolKit to "../ugene/src/_debug" folder

For *nix users:

  1. installation paths may be set up in ugene_globals.pri
  2. qmake -r (Fedora: qmake-qt5 -r)
  3. make -j 4
  4. sudo make install
  5. ugene -ui

Note: usually, make builds a release version of UGENE. However, on certain platforms default target is debug. To enforce release build use make release or make all.

Some more information you can see in installer/_common_data/README file.

Build with CUDA

  1. Download and install required software from for your OS

  2. Make sure that some system variable are set:



  3. cd ./src and open ugene_globals.pri, find and set variable UGENE_CUDA_DETECTED = 1

Build with OpenCL

  1. Download and install video driver wich supports OpenCL
  2. Download OpenCL headers from or find them in video vendor SDK directory.
  3. make sure that you have system variable is set correctly: OPENCL_INC_PATH=/path_where_open_cl_installed
  4. cd ./src and open ugene_globals.pri, find and set variable UGENE_OPENCL_DETECTED = 1

Notes: UGENE_CELL flag in ugene_globals should be uncommented when building on Cell BE platform

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