diff --git a/HISTORY.rst b/HISTORY.rst
index b677f3c75..313cdc44a 100644
--- a/HISTORY.rst
+++ b/HISTORY.rst
@@ -9,12 +9,14 @@ HEAD (unreleased)
 End-User Summary
 ================
 
+- Adding "not hom. alt." filter setting.
 - Allowing users to easily copy case UUID by icon in case heading.
 - Fixing bug that made the user icon top right disappear.
 
 Full Change List
 ================
 
+- Adding "not hom. alt." filter setting.
 - Improving admin configuration documentation.
 - Extending admin tuning documentation.
 - Allowing users to easily copy case UUID by icon in case heading.
diff --git a/variants/forms.py b/variants/forms.py
index d1467a865..33272ec9d 100644
--- a/variants/forms.py
+++ b/variants/forms.py
@@ -126,6 +126,7 @@ class Meta:
     ("ref", "0/0"),
     ("het", "0/1"),
     ("hom", "1/1"),
+    ("non-hom", "0/0 or 0/1"),
     ("variant", "variant"),
     ("non-variant", "non-variant"),
     ("non-reference", "non-reference"),
@@ -178,6 +179,7 @@ class Meta:
     "ref": ("0/0", "0|0", "0"),
     "het": ("0/1", "0|1", "1/0", "1|0", "1"),
     "hom": ("1/1", "1|1", "1"),
+    "non-hom": ("0/0", "0|0", "0", "0/1", "0|1", "1/0", "1|0", "1"),
     "reference": ("0/0", "0|0", "0"),
     "variant": ("1/0", "1|0", "0/1", "0|1", "1/1", "1|1", "1"),
     "non-variant": ("0/0", "./.", "0"),
diff --git a/variants/tests/test_queries.py b/variants/tests/test_queries.py
index ad3a63e81..09e0609b3 100644
--- a/variants/tests/test_queries.py
+++ b/variants/tests/test_queries.py
@@ -2192,6 +2192,15 @@ def test_genotype_gt_variant_export(self):
     def test_genotype_gt_variant_vcf(self):
         self.run_query(CaseExportVcfQuery, {"%s_gt" % self.patient: "variant"}, 6)
 
+    def test_genotype_gt_non_hom_filter(self):
+        self.run_query(CasePrefetchQuery, {"%s_gt" % self.patient: "non-hom"}, 6)
+
+    def test_genotype_gt_non_hom_export(self):
+        self.run_query(CaseExportTableQuery, {"%s_gt" % self.patient: "non-hom"}, 6)
+
+    def test_genotype_gt_non_hom_vcf(self):
+        self.run_query(CaseExportVcfQuery, {"%s_gt" % self.patient: "non-hom"}, 6)
+
     def test_genotype_gt_non_variant_filter(self):
         self.run_query(CasePrefetchQuery, {"%s_gt" % self.patient: "non-variant"}, 2)