diff --git a/@xen-orchestra/backups/ImportVmBackup.js b/@xen-orchestra/backups/ImportVmBackup.js
index 5b00e740185..11694257123 100644
--- a/@xen-orchestra/backups/ImportVmBackup.js
+++ b/@xen-orchestra/backups/ImportVmBackup.js
@@ -30,7 +30,12 @@ exports.ImportVmBackup = class ImportVmBackup {
     } else {
       assert.strictEqual(metadata.mode, 'delta')
 
-      backup = await adapter.readDeltaVmBackup(metadata)
+      const ignoredVdis = new Set(
+        Object.entries(this._importDeltaVmSettings.mapVdisSrs)
+          .filter(([_, srUuid]) => srUuid === null)
+          .map(([vdiUuid]) => vdiUuid)
+      )
+      backup = await adapter.readDeltaVmBackup(metadata, ignoredVdis)
       Object.values(backup.streams).forEach(stream => watchStreamSize(stream, sizeContainer))
     }
 
diff --git a/@xen-orchestra/backups/RemoteAdapter.js b/@xen-orchestra/backups/RemoteAdapter.js
index 7ae0d95a779..b1deec4f600 100644
--- a/@xen-orchestra/backups/RemoteAdapter.js
+++ b/@xen-orchestra/backups/RemoteAdapter.js
@@ -6,6 +6,7 @@ const fromCallback = require('promise-toolbox/fromCallback')
 const fromEvent = require('promise-toolbox/fromEvent')
 const pDefer = require('promise-toolbox/defer')
 const groupBy = require('lodash/groupBy.js')
+const pickBy = require('lodash/pickBy.js')
 const { dirname, join, normalize, resolve } = require('path')
 const { createLogger } = require('@xen-orchestra/log')
 const { Constants, createVhdDirectoryFromStream, openVhd, VhdAbstract, VhdDirectory, VhdSynthetic } = require('vhd-lib')
@@ -576,14 +577,15 @@ class RemoteAdapter {
     return stream
   }
 
-  async readDeltaVmBackup(metadata) {
+  async readDeltaVmBackup(metadata, ignoredVdis) {
     const handler = this._handler
-    const { vbds, vdis, vhds, vifs, vm } = metadata
+    const { vbds, vhds, vifs, vm } = metadata
     const dir = dirname(metadata._filename)
+    const vdis = ignoredVdis === undefined ? metadata.vdis : pickBy(metadata.vdis, vdi => !ignoredVdis.has(vdi.uuid))
 
     const streams = {}
-    await asyncMapSettled(Object.keys(vdis), async id => {
-      streams[`${id}.vhd`] = await this._createSyntheticStream(handler, join(dir, vhds[id]))
+    await asyncMapSettled(Object.keys(vdis), async ref => {
+      streams[`${ref}.vhd`] = await this._createSyntheticStream(handler, join(dir, vhds[ref]))
     })
 
     return {
diff --git a/@xen-orchestra/backups/_deltaVm.js b/@xen-orchestra/backups/_deltaVm.js
index 0717c16a374..d75475f5dd4 100644
--- a/@xen-orchestra/backups/_deltaVm.js
+++ b/@xen-orchestra/backups/_deltaVm.js
@@ -20,6 +20,9 @@ exports.TAG_COPY_SRC = TAG_COPY_SRC
 
 const ensureArray = value => (value === undefined ? [] : Array.isArray(value) ? value : [value])
 const resolveUuid = async (xapi, cache, uuid, type) => {
+  if (uuid == null) {
+    return uuid
+  }
   let ref = cache.get(uuid)
   if (ref === undefined) {
     ref = await xapi.call(`${type}.get_by_uuid`, uuid)
diff --git a/CHANGELOG.unreleased.md b/CHANGELOG.unreleased.md
index 44cac70a165..f33bc07c0c8 100644
--- a/CHANGELOG.unreleased.md
+++ b/CHANGELOG.unreleased.md
@@ -10,6 +10,7 @@
 - [REST API] Expose networks, VBDs, VDIs and VIFs
 - [Console] Supports host and VM consoles behind HTTP proxies [#6133](https://github.com/vatesfr/xen-orchestra/pull/6133)
 - [Install patches] Disable patch installation when `High Availability` is enabled (PR [#6145](https://github.com/vatesfr/xen-orchestra/pull/6145))
+- [Delta Backup/Restore] Ability to ignore some VDIs (PR [#6143](https://github.com/vatesfr/xen-orchestra/pull/6143))
 
 ### Bug fixes
 
@@ -44,5 +45,5 @@
 - vhd-cli minor
 - @xen-orchestra/backups minor
 - @xen-orchestra/proxy minor
-- xo-server patch
+- xo-server minor
 - xo-web minor
diff --git a/packages/xo-web/src/common/intl/messages.js b/packages/xo-web/src/common/intl/messages.js
index 08dfeed9fca..da23ebdf5b9 100644
--- a/packages/xo-web/src/common/intl/messages.js
+++ b/packages/xo-web/src/common/intl/messages.js
@@ -1826,6 +1826,7 @@ const messages = {
     'This VM contains a duplicate MAC address or has the same MAC address as another running VM. Do you want to continue?',
   vmsWithDuplicatedMacAddressesMessage:
     '{nVms, number} VM{nVms, plural, one {} other {s}} contain{nVms, plural, one {s} other {}} duplicate MAC addresses or {nVms, plural, one {has} other {have}} the same MAC addresses as other running VMs. Do you want to continue?',
+  ignoreVdi: 'Ignore this VDI',
 
   // ----- Servers -----
   enableServerErrorTitle: 'Enable server',
diff --git a/packages/xo-web/src/common/xo/choose-sr-for-each-vdis-modal/index.js b/packages/xo-web/src/common/xo/choose-sr-for-each-vdis-modal/index.js
index a0966884030..28b0c6b345a 100644
--- a/packages/xo-web/src/common/xo/choose-sr-for-each-vdis-modal/index.js
+++ b/packages/xo-web/src/common/xo/choose-sr-for-each-vdis-modal/index.js
@@ -1,14 +1,16 @@
 import Collapse from 'collapse'
 import Component from 'base-component'
+import Icon from 'icon'
 import PropTypes from 'prop-types'
 import React from 'react'
+import Tooltip from 'tooltip'
+import { Container, Col } from 'grid'
 import { isEmpty, map } from 'lodash'
+import { isSrWritable } from 'xo'
 import { Vdi } from 'render-xo-item'
 
 import _ from '../../intl'
 import SingleLineRow from '../../single-line-row'
-import { Container, Col } from 'grid'
-import { isSrWritable } from 'xo'
 import { SelectSr } from '../../select-objects'
 
 const Collapsible = ({ collapsible, children, ...props }) =>
@@ -29,6 +31,7 @@ Collapsible.propTypes = {
 
 export default class ChooseSrForEachVdisModal extends Component {
   static propTypes = {
+    ignorableVdis: PropTypes.bool,
     mainSrPredicate: PropTypes.func,
     onChange: PropTypes.func.isRequired,
     srPredicate: PropTypes.func,
@@ -53,6 +56,7 @@ export default class ChooseSrForEachVdisModal extends Component {
   render() {
     const { props } = this
     const {
+      ignorableVdis = false,
       mainSrPredicate = isSrWritable,
       placeholder,
       srPredicate = mainSrPredicate,
@@ -64,7 +68,7 @@ export default class ChooseSrForEachVdisModal extends Component {
       <div>
         <SelectSr
           onChange={this._onChangeMainSr}
-          placeholder={placeholder !== undefined ? placeholder : 'chooseSrForEachVdisModalMainSr'}
+          placeholder={placeholder !== undefined ? placeholder : _('chooseSrForEachVdisModalMainSr')}
           predicate={mainSrPredicate}
           required
           value={mainSr}
@@ -84,7 +88,9 @@ export default class ChooseSrForEachVdisModal extends Component {
               </SingleLineRow>
               {map(vdis, vdi => (
                 <SingleLineRow key={vdi.uuid}>
-                  <Col size={6}>{vdi.name !== undefined ? vdi.name : <Vdi id={vdi.id} showSize />}</Col>
+                  <Col size={ignorableVdis ? 5 : 6}>
+                    {vdi.name !== undefined ? vdi.name : <Vdi id={vdi.id} showSize />}
+                  </Col>
                   <Col size={6}>
                     <SelectSr
                       onChange={sr =>
@@ -96,6 +102,22 @@ export default class ChooseSrForEachVdisModal extends Component {
                       value={mapVdisSrs !== undefined && mapVdisSrs[vdi.uuid]}
                     />
                   </Col>
+                  {ignorableVdis && (
+                    <Col size={1}>
+                      <Tooltip content={_('ignoreVdi')}>
+                        <a
+                          role='button'
+                          onClick={() =>
+                            this._onChange({
+                              mapVdisSrs: { ...mapVdisSrs, [vdi.uuid]: null },
+                            })
+                          }
+                        >
+                          <Icon icon='remove' />
+                        </a>
+                      </Tooltip>
+                    </Col>
+                  )}
                 </SingleLineRow>
               ))}
               <i>{_('optionalEntry')}</i>
diff --git a/packages/xo-web/src/xo-app/backup/restore/restore-backups-modal-body.js b/packages/xo-web/src/xo-app/backup/restore/restore-backups-modal-body.js
index fe5f7c04db0..d2d8fbcc393 100644
--- a/packages/xo-web/src/xo-app/backup/restore/restore-backups-modal-body.js
+++ b/packages/xo-web/src/xo-app/backup/restore/restore-backups-modal-body.js
@@ -19,9 +19,14 @@ export default class RestoreBackupsModalBody extends Component {
 
   _getDisks = createSelector(
     () => this.state.backup,
-    backup =>
+    () => this.state.targetSrs.mapVdisSrs,
+    (backup, mapVdisSrs) =>
       backup !== undefined && backup.mode === 'delta'
-        ? backup.disks.reduce((vdis, vdi) => ({ ...vdis, [vdi.uuid]: vdi }), {})
+        ? backup.disks.reduce(
+            (vdis, vdi) =>
+              mapVdisSrs !== undefined && mapVdisSrs[vdi.uuid] === null ? vdis : { ...vdis, [vdi.uuid]: vdi },
+            {}
+          )
         : {}
   )
 
@@ -40,6 +45,7 @@ export default class RestoreBackupsModalBody extends Component {
           <div>
             <div className='mb-1'>
               <ChooseSrForEachVdisModal
+                ignorableVdis
                 onChange={this.linkState('targetSrs')}
                 placeholder={_('importBackupModalSelectSr')}
                 required