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What is the impact of regulatory guidance and expiry of drug patents on dementia drug prescriptions in England: a trend analysis in the Clinical Practice Research Datalink

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DementiaDrugsCPRD

This respository contains the code to reproduce the analysis from the following paper:

Walker, V. M., Davies, N. M., Kehoe, P. G., & Martin, R. M. (2018). What is the impact of regulatory guidance and expiry of drug patents on dementia drug prescriptions in England? A trend analysis in the Clinical Practice Research Datalink. Alzheimer’s Research & Therapy, 10, 51. https://doi.org/10.1186/s13195-018-0379-6

Using this code

To run this code, run the file 'DementiaDrugsCPRD.do'. All other files are called when required from this file. The code is setup to work from a master file that contains a record for each patient, along with their demographic information and relevant dates for diagnoses and treatments. If you would like more information concerning the data setup, please contact venexia.walker@bristol.ac.uk.

Availability of data

The data that support the findings of this study are available from the CPRD but restrictions apply to the availability of these data, which were used under license for the current study, and so are not publicly available.

Funding statement

This work was supported by the Perros Trust and the Integrative Epidemiology Unit. The Integrative Epidemiology Unit issupported by the Medical Research Council and the University of Bristol [grant number MC_UU_12013/9]. PGK has a Professorship supported by the Sigmund Gestetner Foundation.  

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What is the impact of regulatory guidance and expiry of drug patents on dementia drug prescriptions in England: a trend analysis in the Clinical Practice Research Datalink

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