diff --git a/packages/vite/src/node/server/middlewares/transform.ts b/packages/vite/src/node/server/middlewares/transform.ts
index 65708262d9c0f1..6b9a57684de06c 100644
--- a/packages/vite/src/node/server/middlewares/transform.ts
+++ b/packages/vite/src/node/server/middlewares/transform.ts
@@ -39,6 +39,7 @@ export function transformMiddleware(
   return async (req, res, next) => {
     if (
       req.method !== 'GET' ||
+      req.headers.accept?.includes('text/html') ||
       knownIgnoreList.has(req.url!)
     ) {
       return next()