Skip to content
master
Switch branches/tags
Code

Latest commit

 

Git stats

Files

Permalink
Failed to load latest commit information.
Type
Name
Latest commit message
Commit time
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 

PyMut

PyMut is a Python 3 module that fills the gap between machine learning and bioinformatics, providing methods that help in the prediction of pathology in protein mutations. Using PyMut you can compute features, train predictors, evaluate them, predict the pathology of mutations, select the best features...

Installation

We recommend using Anaconda, a free distribution of the SciPy stack. To install PyMut, follow these steps:

Download anaconda with Python 3.5 for your platform (Windows, Linux or OSX), and install (double-click in Windows), or run in Linux of OSX:

`bash Anaconda3-4.3.0-Linux-x86_64.sh`
  1. Create an anaconda Python 3 environment (we will name it pymut), and activate the environment:

    conda create python=3 --name pymut

    source activate pymut

  2. Install PyMut:

    pip install pymut

Tutorial

Visit the PyMut tutorial to see a full example of usage of PyMut. In the tutorial we show how to:

  • Compute features that describe mutations and plot their distribution.
  • Train classifiers, evaluate them using cross-validation and plot their ROC curves.
  • Select the best features.
  • Train a pathology predictor.
  • Predict the pathology of mutations using our newly trained predictor.

Sample plots generated by PyMut

About

Machine learning methods for the prediction of pathology in protein mutations, as in the PMut predictor.

Topics

Resources

License

Packages

No packages published