diff --git a/packages/rspack/src/Compiler.ts b/packages/rspack/src/Compiler.ts
index 8eafd94f8ef..51f4592db9a 100644
--- a/packages/rspack/src/Compiler.ts
+++ b/packages/rspack/src/Compiler.ts
@@ -403,7 +403,9 @@ class Compiler {
 		childCompiler.root = this.root;
 		if (Array.isArray(plugins)) {
 			for (const plugin of plugins) {
-				plugin.apply(childCompiler);
+				if (plugin) {
+					plugin.apply(childCompiler);
+				}
 			}
 		}
 		for (const name in this.hooks) {
diff --git a/packages/rspack/src/config/zod.ts b/packages/rspack/src/config/zod.ts
index fb103845981..3fee24c6215 100644
--- a/packages/rspack/src/config/zod.ts
+++ b/packages/rspack/src/config/zod.ts
@@ -26,6 +26,18 @@ const mode = z.enum(["development", "production", "none"]);
 export type Mode = z.infer<typeof mode>;
 //#endregion
 
+//#region Falsy
+const falsy = z.union([
+	z.literal(false),
+	z.literal(0),
+	z.literal(""),
+	z.null(),
+	z.undefined()
+]);
+
+export type Falsy = z.infer<typeof falsy>;
+//#endregion
+
 //#region Entry
 const rawPublicPath = z.string();
 export type RawPublicPath = z.infer<typeof rawPublicPath>;
@@ -459,7 +471,7 @@ const ruleSetRule: z.ZodType<RuleSetRule> = baseRuleSetRule.extend({
 	rules: z.lazy(() => ruleSetRule.array()).optional()
 });
 
-const ruleSetRules = z.array(z.literal("...").or(ruleSetRule));
+const ruleSetRules = z.array(z.literal("...").or(ruleSetRule).or(falsy));
 export type RuleSetRules = z.infer<typeof ruleSetRules>;
 
 const assetParserDataUrlOptions = z.strictObject({
@@ -888,7 +900,8 @@ export type RspackPluginFunction = (this: Compiler, compiler: Compiler) => void;
 
 const plugin = z.union([
 	z.custom<RspackPluginInstance>(),
-	z.custom<RspackPluginFunction>()
+	z.custom<RspackPluginFunction>(),
+	falsy,
 ]);
 const plugins = plugin.array();
 export type Plugins = z.infer<typeof plugins>;
@@ -1062,9 +1075,9 @@ const experiments = z.strictObject({
 						val
 					)}' has been deprecated, please switch to 'experiments.newSplitChunks = true' to use webpack's behavior.
  	See the discussion ${termlink(
-		"here",
-		"https://github.com/web-infra-dev/rspack/discussions/4168"
-	)}`
+						"here",
+						"https://github.com/web-infra-dev/rspack/discussions/4168"
+					)}`
 				);
 			}
 			return true;
diff --git a/packages/rspack/src/rspack.ts b/packages/rspack/src/rspack.ts
index 2ee3d658475..2e892f06c5d 100644
--- a/packages/rspack/src/rspack.ts
+++ b/packages/rspack/src/rspack.ts
@@ -70,7 +70,7 @@ function createCompiler(userOptions: RspackOptions): Compiler {
 		for (const plugin of options.plugins) {
 			if (typeof plugin === "function") {
 				(plugin as RspackPluginFunction).call(compiler, compiler);
-			} else {
+			} else if (plugin) {
 				plugin.apply(compiler);
 			}
 		}
@@ -148,8 +148,10 @@ function rspack(
 	} else {
 		const { compiler, watch } = create();
 		if (watch) {
-			util.deprecate(() => {},
-			"A 'callback' argument needs to be provided to the 'rspack(options, callback)' function when the 'watch' option is set. There is no way to handle the 'watch' option without a callback.")();
+			util.deprecate(
+				() => { },
+				"A 'callback' argument needs to be provided to the 'rspack(options, callback)' function when the 'watch' option is set. There is no way to handle the 'watch' option without a callback."
+			)();
 		}
 		return compiler;
 	}
diff --git a/packages/rspack/src/rspackOptionsApply.ts b/packages/rspack/src/rspackOptionsApply.ts
index a3be3998ecb..0c97297ca6f 100644
--- a/packages/rspack/src/rspackOptionsApply.ts
+++ b/packages/rspack/src/rspackOptionsApply.ts
@@ -149,7 +149,7 @@ export function optionsApply_compat(
 }
 
 export class RspackOptionsApply {
-	constructor() {}
+	constructor() { }
 	process(options: RspackOptionsNormalized, compiler: Compiler) {
 		assert(
 			options.output.path,
@@ -182,7 +182,7 @@ export class RspackOptionsApply {
 			for (const item of minimizer) {
 				if (typeof item === "function") {
 					(item as RspackPluginFunction).call(compiler, compiler);
-				} else if (item !== "...") {
+				} else if (item !== "..." && item) {
 					item.apply(compiler);
 				}
 			}
diff --git a/packages/rspack/tests/configCases/plugins/plugins-falsy/a.js b/packages/rspack/tests/configCases/plugins/plugins-falsy/a.js
new file mode 100644
index 00000000000..58c57157d36
--- /dev/null
+++ b/packages/rspack/tests/configCases/plugins/plugins-falsy/a.js
@@ -0,0 +1 @@
+export default "test";
diff --git a/packages/rspack/tests/configCases/plugins/plugins-falsy/index.js b/packages/rspack/tests/configCases/plugins/plugins-falsy/index.js
new file mode 100644
index 00000000000..f2944e9172d
--- /dev/null
+++ b/packages/rspack/tests/configCases/plugins/plugins-falsy/index.js
@@ -0,0 +1,5 @@
+const test = require("./a");
+
+it("should work with falsy plugins", function () {
+	expect(test.default).toBe("test");
+});
diff --git a/packages/rspack/tests/configCases/plugins/plugins-falsy/webpack.config.js b/packages/rspack/tests/configCases/plugins/plugins-falsy/webpack.config.js
new file mode 100644
index 00000000000..60669738df4
--- /dev/null
+++ b/packages/rspack/tests/configCases/plugins/plugins-falsy/webpack.config.js
@@ -0,0 +1,22 @@
+const nullValue = null;
+const undefinedValue = undefined;
+const falseValue = false;
+const zeroValue = 0;
+const emptyStringValue = "";
+
+class FailPlugin {
+	apply() {
+		throw new Error("FailedPlugin");
+	}
+}
+
+/** @type {import("../../../../src/index").RspackOptions} */
+module.exports = {
+	plugins: [
+		undefinedValue && new FailPlugin(),
+		nullValue && new FailPlugin(),
+		falseValue && new FailPlugin(),
+		zeroValue && new FailPlugin(),
+		emptyStringValue && new FailPlugin()
+	]
+};