diff --git a/.changeset/purple-buses-prove.md b/.changeset/purple-buses-prove.md
new file mode 100644
index 000000000000..c1e4876c9c53
--- /dev/null
+++ b/.changeset/purple-buses-prove.md
@@ -0,0 +1,5 @@
+---
+'astro': patch
+---
+
+Remove StreamingCompatibleResponse polyfill
diff --git a/packages/astro/src/runtime/server/render/page.ts b/packages/astro/src/runtime/server/render/page.ts
index cabbe8dae72d..74e8a45b7691 100644
--- a/packages/astro/src/runtime/server/render/page.ts
+++ b/packages/astro/src/runtime/server/render/page.ts
@@ -2,7 +2,6 @@ import type { RouteData, SSRResult } from '../../../@types/astro';
 import { renderComponentToString, type NonAstroPageComponent } from './component.js';
 import type { AstroComponentFactory } from './index';
 
-import { createResponse } from '../response.js';
 import { isAstroComponentFactory } from './astro/index.js';
 import { renderToReadableStream, renderToString } from './astro/render.js';
 import { encoder } from './common.js';
@@ -64,6 +63,6 @@ export async function renderPage(
 		body = encoder.encode(body);
 		headers.set('Content-Length', body.byteLength.toString());
 	}
-	const response = createResponse(body, { ...init, headers });
+	const response = new Response(body, { ...init, headers });
 	return response;
 }
diff --git a/packages/astro/src/runtime/server/response.ts b/packages/astro/src/runtime/server/response.ts
deleted file mode 100644
index bcfda19aa13d..000000000000
--- a/packages/astro/src/runtime/server/response.ts
+++ /dev/null
@@ -1,80 +0,0 @@
-import { streamAsyncIterator } from './util.js';
-
-const isNodeJS =
-	typeof process === 'object' && Object.prototype.toString.call(process) === '[object process]';
-
-let StreamingCompatibleResponse: typeof Response | undefined;
-
-function createResponseClass() {
-	StreamingCompatibleResponse = class extends Response {
-		#isStream: boolean;
-		#body: any;
-		constructor(body?: BodyInit | null, init?: ResponseInit) {
-			let isStream = body instanceof ReadableStream;
-			super(isStream ? null : body, init);
-			this.#isStream = isStream;
-			this.#body = body;
-		}
-
-		get body() {
-			return this.#body;
-		}
-
-		async text(): Promise<string> {
-			if (this.#isStream && isNodeJS) {
-				let decoder = new TextDecoder();
-				let body = this.#body;
-				let out = '';
-				for await (let chunk of streamAsyncIterator(body)) {
-					out += decoder.decode(chunk);
-				}
-				return out;
-			}
-			return super.text();
-		}
-
-		async arrayBuffer(): Promise<ArrayBuffer> {
-			if (this.#isStream && isNodeJS) {
-				let body = this.#body;
-				let chunks: Uint8Array[] = [];
-				let len = 0;
-				for await (let chunk of streamAsyncIterator(body)) {
-					chunks.push(chunk);
-					len += chunk.length;
-				}
-				let ab = new Uint8Array(len);
-				let offset = 0;
-				for (const chunk of chunks) {
-					ab.set(chunk, offset);
-					offset += chunk.length;
-				}
-				return ab;
-			}
-			return super.arrayBuffer();
-		}
-
-		clone() {
-			return new StreamingCompatibleResponse!(this.#body, {
-				status: this.status,
-				statusText: this.statusText,
-				headers: this.headers,
-			});
-		}
-	};
-
-	return StreamingCompatibleResponse;
-}
-
-type CreateResponseFn = (body?: BodyInit | null, init?: ResponseInit) => Response;
-
-export const createResponse: CreateResponseFn = isNodeJS
-	? (body, init) => {
-			if (typeof body === 'string' || ArrayBuffer.isView(body)) {
-				return new Response(body, init);
-			}
-			if (typeof StreamingCompatibleResponse === 'undefined') {
-				return new (createResponseClass())(body, init);
-			}
-			return new StreamingCompatibleResponse(body, init);
-	  }
-	: (body, init) => new Response(body, init);