diff --git a/.github/workflows/main.yml b/.github/workflows/main.yml
new file mode 100644
index 00000000..ebafbfc0
--- /dev/null
+++ b/.github/workflows/main.yml
@@ -0,0 +1,25 @@
+name: Semgrep - Team Vaccine
+on:
+  workflow_dispatch: {}
+  pull_request: {}
+  push:
+    branches:
+      - main
+      - master
+    paths:
+      - .github/workflows/semgrep.yml
+  schedule:
+    # random HH:MM to avoid a load spike on GitHub Actions at 00:00
+    - cron: '30 1 * * *'
+jobs:
+  semgrep:
+    name: semgrep/ci
+    runs-on: ubuntu-20.04
+    env:
+      SEMGREP_APP_TOKEN: ${{ secrets.SEMGREP_APP_TOKEN_VACCINE }}
+    container:
+      image: returntocorp/semgrep
+    if: (github.actor != 'dependabot[bot]')
+    steps:
+      - uses: actions/checkout@v3
+      - run: semgrep ci