diff --git a/packages/react-dom/src/client/ReactDOMHostConfig.js b/packages/react-dom/src/client/ReactDOMHostConfig.js
index 43f5077932619..74877c1591e75 100644
--- a/packages/react-dom/src/client/ReactDOMHostConfig.js
+++ b/packages/react-dom/src/client/ReactDOMHostConfig.js
@@ -392,7 +392,7 @@ export const scheduleTimeout: any =
 export const cancelTimeout: any =
   typeof clearTimeout === 'function' ? clearTimeout : (undefined: any);
 export const noTimeout = -1;
-const localPromise = Promise;
+const localPromise = typeof Promise === 'function' ? Promise : undefined;
 
 // -------------------
 //     Microtasks