diff --git a/CHANGES.rst b/CHANGES.rst
index 40bf792..692464e 100644
--- a/CHANGES.rst
+++ b/CHANGES.rst
@@ -3,7 +3,7 @@
 =========
 
 
-5.1.0 (unreleased)
+5.1.0 (2023-01-03)
 ==================
 
 - Fix crash when the environment variable `PYTHONOPTIMIZED` is set to `2`
diff --git a/buildout.cfg b/buildout.cfg
index 0cd2ad4..906cbf2 100644
--- a/buildout.cfg
+++ b/buildout.cfg
@@ -29,5 +29,5 @@ eggs = zope.component [test,zcml,security,persistentregistry,hook]
 
 [python]
 recipe = zc.recipe.egg
-interpreter = python
+interpreter = py
 eggs = ${test:eggs}
diff --git a/setup.py b/setup.py
index 78caab5..6e278e0 100644
--- a/setup.py
+++ b/setup.py
@@ -62,7 +62,7 @@ def read(*rnames):
 
 setup(
     name='zope.component',
-    version='5.1.0.dev0',
+    version='5.1.0',
     url='https://github.com/zopefoundation/zope.component',
     project_urls={
         'Documentation': 'https://zopecomponent.readthedocs.io/',
diff --git a/tox.ini b/tox.ini
index 9f551be..4c19bb1 100644
--- a/tox.ini
+++ b/tox.ini
@@ -7,7 +7,10 @@ envlist =
     py37
     py38
     py39
+    py310
+    py311
     py27-minimal
+    py310-optimized
     pypy
     pypy3
     docs