I am a Computational Biologist at the Institute of Medical Statistics and Computational Biology at the University of Cologne. I love modeling complex systems to drive scientific discovery! Currently, I am a member of the CompBio work group:

My research focuses on the quantification of the RNA life cycle. In this context, I am the main developer of the software tool 'Halfpipe', which quantifies RNA half-lives.

In addition, I have developed a simulation framework called RNAmetabol that can be used for experimental design of RNA metabolism experiments with 4sU labeling.

[1] Müller et al. (2025) Halfpipe: a tool for analyzing metabolic labeling RNA-seq data to quantify RNA half-lives. NAR Genomics and Bioinformatics.

[2] Müller et al. (2024) Nuclear export is a limiting factor in eukaryotic mRNA metabolism. PLOS Computational Biology.