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@biosimulators

BioSimulators

Enabling more comprehensive and more predictive biological models through standardized simulation tools

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More comprehensive and more predictive models have the potential to advance biology, bioengineering, and medicine. Building more predictive models will likely require the collaborative efforts of many investigators. This requires teams to be able to share and reuse model components and modeling tools. Despite extensive efforts to develop standards such as the COMBINE/OMEX archive format, the Kinetic Simulation Algorithm Ontology (KiSAO), the Systems Biology Markup Language (SBML), and the Simulation Experiment Description Markup Language (SED-ML) and repositories such as BioModels and the Physiome Model Repository, it is still often difficult to share, reuse, and combine models and modeling tools. One challenge to sharing and reusing models is the disparate formats, model repositories, and simulation tools for different types of models. The proliferation of numerous similar formats, repositories, and tools makes it difficult, especially for non-experts, to find models and to find an appropriate simulation tool for each model. In addition, the existing model repositories have limited capabilities for sharing associated resources such as training data, simulation experiments, and visualizations. BioSimulators addressses these challenges by making it easier for researchers to share and reuse modeling tools.

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  1. Biosimulators Public

    Registry of containerized biosimulation tools that support a standard command-line interface

    Python 13

  2. Biosimulators_tutorials Public

    Tutorials for BioSimulators

    Jupyter Notebook 2

  3. Biosimulators_utils Public

    Utilities for building standardized command-line interfaces for biosimulation software packages

    Python 4 6

  4. Biosimulators_simulator_template Public template

    Template for a repository for building a BioSimulators-compliant command-line interface and Dockerfile for a biosimulation program

    Python 4 3

  5. Biosimulators_test_suite Public

    Tool for validating that biosimulation software tools implement the BioSimulators standards for simulators

    Python 7 2

  6. biosimulators.github.io Public

    Summary of the technical documentation for BioSimulators

    Python

Repositories

Showing 10 of 39 repositories
  • Biosimulators Public

    Registry of containerized biosimulation tools that support a standard command-line interface

    Python 13 MIT 0 14 7 Updated Mar 17, 2025
  • compose-server Public

    This repo is intended to replace both the bio-check and bio-compose-server repos. The aforementioned repos will be archived.

    Python 0 Apache-2.0 0 0 1 Updated Mar 12, 2025
  • Biosimulators_utils Public

    Utilities for building standardized command-line interfaces for biosimulation software packages

    Python 4 MIT 6 39 5 Updated Mar 6, 2025
  • Biosimulators_COPASI Public

    COPASI biochemical network simulation program via BioSimulators-compliant command-line interface and Docker container

    Python 2 MIT 3 6 1 Updated Mar 6, 2025
  • bio-compose-server Public Forked from biosimulators/bio-check

    Backend for BioCompose: a microservices-based data service leveraging Kubernetes for efficient orchestration of bio-chemical simulation comparisons.

    Python 1 Apache-2.0 1 0 0 Updated Feb 4, 2025
  • Biosimulators_tellurium Public

    tellurium biochemical network simulation program via BioSimulators-compliant command-line interface and Docker container

    Python 2 MIT 2 1 3 Updated Jan 8, 2025
  • bio-check Public

    A microservices-based data service leveraging Kubernetes for efficient orchestration of bio-chemical simulation comparisons.

    Python 1 Apache-2.0 1 0 1 Updated Jan 7, 2025
  • bsvs Public

    A high-level Python client for the Biological Simulation Verification Service REST API.

    Python 0 Apache-2.0 0 0 0 Updated Dec 23, 2024
  • bio-compose Public

    Create, execute, and introspect reproducible composite simulations of dynamic biological systems.

    Jupyter Notebook 0 Apache-2.0 0 0 1 Updated Dec 22, 2024
  • Biosimulators_test_suite Public

    Tool for validating that biosimulation software tools implement the BioSimulators standards for simulators

    Python 7 MIT 2 22 7 Updated Nov 22, 2024