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Cardiotensor

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A Python package for calculating 3D cardiomyocyte orientations in heart images.

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Example Slice
Helical angle map of a heart scanned using synchrtron X-ray imaging.

Introduction

Cardiotensor is a user-friendly and memory-efficient toolkit designed for analyzing the orientation of cardiomyocyte fibers in large heart imaging datasets. It uses advanced image processing techniques to help researchers to accurately quantify 3D cardiomyocyte orientations with high efficiency.

Installation

Clone the repository and install the package using pip:

git clone https://github.com/JosephBrunet/cardiotensor.git
cd cardiotensor
pip install .

⚠️ Require python 3.10 or newer

Documentation

cardiotensor's documentation is available at josephbrunet.fr/cardiotensor/

Getting Started

Have a look at our simple example that runs you through all the commands of the package

More Information

This package uses the structure-tensor package to calculate the structure tensor, extending its capabilities for cardiac imaging.

License

This project is licensed under the MIT License. See the LICENSE file for details.

Contributing

Contributions are welcome! If you encounter a bug or have suggestions for new features:

  • Report an Issue: Open an issue in the repository.
  • Submit a Pull Request: Fork the repository, make changes, and submit a pull request.

For major changes, please discuss them in an issue first.

Contact

For questions, feedback, or support, please contact the maintainers at [j.brunet@ucl.ac.uk].

Reference

Brunet, J., Cook, A. C., Walsh, C. L., Cranley, J., Tafforeau, P., Engel, K., Arthurs, O., Berruyer, C., Burke O’Leary, E., Bellier, A., et al. (2024). Multidimensional analysis of the adult human heart in health and disease using hierarchical phase-contrast tomography. Radiology, 312(1), e232731. https://doi.org/10.1148/radiol.232731. [PDF]

@article{brunet2024multidimensional,
  title={Multidimensional analysis of the adult human heart in health and disease using hierarchical phase-contrast tomography},
  author={Brunet, Joseph and Cook, Andrew C and Walsh, Claire L and Cranley, James and Tafforeau, Paul and Engel, Klaus and Arthurs, Owen and Berruyer, Camille and Burke O’Leary, Emer and Bellier, Alexandre and others},
  journal={Radiology},
  volume={312},
  number={1},
  pages={e232731},
  year={2024},
  publisher={Radiological Society of North America}
}

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Toolkit designed for quantifying 3D cardiomyocytes orientations in heart images

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