e3_table

This repository contains a spreadsheet dataset of known human and yeast E3 protein ligases, each annotated with position specific disorder and Anchor binding score predictions. The main goal of the data was to find human equivalents of the San1 protein occurring in yeast, which was recently found to have the ability to recognize disordered substrates directly, without relying on a chaperone protein. The disorder and anchor features are used to define a San1 similarity score, and the spreadsheets make it possible to sort the entries by this score - and to recalculate San1 similarity scores for different parameters settings. A small version of this file was included with the publications of our paper. This larger file file contains all data for each individual protein, and supports recalculation of scores with different parameters.