when nsets set to 23, it takes too long to output pdf

[20182531027]

I have 23 samples to find the differences among samples, when nsets was set to 10, 15, 19, it can soon formed result file;
but when i adjust the nsets as 23, it has been seven days, but it still doesn't run out the result.
will you be kind enough to tell me what's wrong with that? the UpSetR really makes me upset now.
the code is as follow:
upset(cq,sets.bar.color = "#56B4E9",order.by = "freq",empty.intersections = "on",nsets=23)